5-(Ethylthio)-1H-tetrazole
- Product Name
- 5-(Ethylthio)-1H-tetrazole
- CAS No.
- 89797-68-2
- Chemical Name
- 5-(Ethylthio)-1H-tetrazole
- Synonyms
- ETT;ACTIVATOR;ETT Activator;ACTIVATOR REAGENT;5-Ethyltio-1H-Tetrazole;UT2H;OCTN1;SLC22A4;Ethylthio H;5-(Ethylthio)-1
- CBNumber
- CB3104462
- Molecular Formula
- C3H6N4S
- Formula Weight
- 130.17
- MOL File
- 89797-68-2.mol
5-(Ethylthio)-1H-tetrazole Property
- Melting point:
- 72-80 °C(lit.)
- Boiling point:
- 81-82 °C
- Density
- 0.786 g/mL at 25 °C
- Flash point:
- 42 °F
- storage temp.
- 2-8°C
- solubility
- soluble, clear, colorless
- form
- buffered aqueous solution
- pka
- 3.89±0.10(Predicted)
- color
- solid white
- InChIKey
- GONFBOIJNUKKST-UHFFFAOYSA-N
- CAS DataBase Reference
- 89797-68-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn,F
- Risk Statements
- 36/37/38-44-36-20/21/22-11-5
- Safety Statements
- 26-35-36/37-16-36
- RIDADR
- UN 1648 3/PG 2
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 4.1
- PackingGroup
- III
- HS Code
- 29299000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H318Causes serious eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SAB1304892
- Product name
- ANTI-SLC22A4 (C-TERM) antibody produced in rabbit
- Purity
- IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 400μl
- Price
- $481
- Updated
- 2024/03/01
- Product number
- L030004
- Product name
- ETT Activator
- Purity
- 0.25M
- Packaging
- 200l
- Price
- $10700
- Updated
- 2024/03/01
- Product number
- L030000
- Product name
- ETT Activator
- Purity
- 0.25 M
- Packaging
- 200L
- Price
- $21270
- Updated
- 2024/03/01
- Product number
- 493805
- Product name
- 5-(Ethylthio)-1H-tetrazole
- Purity
- 95%
- Packaging
- 2g
- Price
- $63.8
- Updated
- 2024/03/01
- Product number
- E0670
- Product name
- 5-(Ethylthio)-1H-tetrazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $28
- Updated
- 2024/03/01
5-(Ethylthio)-1H-tetrazole Chemical Properties,Usage,Production
Chemical Properties
White crystals
Application
5-(Ethylthio)-1H-tetrazole is used a powerful activator in DNA and RNA syntheses.
Preparation
5-(Ethylthio)-1H-Tetrazole is prepared from the corresponding alkyl thiocyanate and sodium azide through a [2?+?3] cycloaddition under phase transfer catalytic conditions (eq 1). The ratio of the solvent (water to toluene) as well as the reaction temperature are important factors in obtaining preparative yields of the alkylthiotetrazoles. 5-Ethylthio-1H-tetrazole has also been prepared using DMF as solvent albeit in much lower yield.
General Description
5-(Ethylthio)-1H-tetrazole (ETT) is an efficient activator, that activates nucleoside phosphoramidites towards condensation with a nucleoside to form dinucleoside phosphates during oligonucleotide synthesis.
Purification Methods
recrystallized from toluene.
5-(Ethylthio)-1H-tetrazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-(Ethylthio)-1H-tetrazole manufacturers
- Product
- 5-(Ethylthio)-1H-tetrazole 89797-68-2
- Price
- US $60.00/KG
- Min. Order
- 1KG
- Purity
- 99.9%
- Supply Ability
- 100000kg
- Release date
- 2024-08-20
- Product
- 5-(Ethylthio)-1H-tetrazole 89797-68-2
- Price
- US $20.00-15.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2024-08-15
- Product
- 5-(Ethylthio)-1H-tetrazole 89797-68-2
- Price
- US $1.00/PCS
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2021-06-11