ChemicalBook > CAS DataBase List > 5-(Ethylthio)-1H-tetrazole

5-(Ethylthio)-1H-tetrazole

Product Name
5-(Ethylthio)-1H-tetrazole
CAS No.
89797-68-2
Chemical Name
5-(Ethylthio)-1H-tetrazole
Synonyms
ETT;ACTIVATOR;ETT Activator;ACTIVATOR REAGENT;5-Ethyltio-1H-Tetrazole;UT2H;OCTN1;SLC22A4;Ethylthio H;5-(Ethylthio)-1
CBNumber
CB3104462
Molecular Formula
C3H6N4S
Formula Weight
130.17
MOL File
89797-68-2.mol
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5-(Ethylthio)-1H-tetrazole Property

Melting point:
72-80 °C(lit.)
Boiling point:
81-82 °C
Density 
0.786 g/mL at 25 °C
Flash point:
42 °F
storage temp. 
2-8°C
solubility 
soluble, clear, colorless
form 
buffered aqueous solution
pka
3.89±0.10(Predicted)
color 
solid white
InChIKey
GONFBOIJNUKKST-UHFFFAOYSA-N
CAS DataBase Reference
89797-68-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn,F
Risk Statements 
36/37/38-44-36-20/21/22-11-5
Safety Statements 
26-35-36/37-16-36
RIDADR 
UN 1648 3/PG 2
WGK Germany 
3
Hazard Note 
Irritant
HazardClass 
4.1
PackingGroup 
III
HS Code 
29299000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H318Causes serious eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB1304892
Product name
ANTI-SLC22A4 (C-TERM) antibody produced in rabbit
Purity
IgG fraction of antiserum, buffered aqueous solution
Packaging
400μl
Price
$481
Updated
2024/03/01
Sigma-Aldrich
Product number
L030004
Product name
ETT Activator
Purity
0.25M
Packaging
200l
Price
$10700
Updated
2024/03/01
Sigma-Aldrich
Product number
L030000
Product name
ETT Activator
Purity
0.25 M
Packaging
200L
Price
$21270
Updated
2024/03/01
Sigma-Aldrich
Product number
493805
Product name
5-(Ethylthio)-1H-tetrazole
Purity
95%
Packaging
2g
Price
$63.8
Updated
2024/03/01
TCI Chemical
Product number
E0670
Product name
5-(Ethylthio)-1H-tetrazole
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$28
Updated
2024/03/01
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5-(Ethylthio)-1H-tetrazole Chemical Properties,Usage,Production

Chemical Properties

White crystals

Application

5-(Ethylthio)-1H-tetrazole is used a powerful activator in DNA and RNA syntheses.

Preparation

5-(Ethylthio)-1H-Tetrazole is prepared from the corresponding alkyl thiocyanate and sodium azide through a [2?+?3] cycloaddition under phase transfer catalytic conditions (eq 1). The ratio of the solvent (water to toluene) as well as the reaction temperature are important factors in obtaining preparative yields of the alkylthiotetrazoles. 5-Ethylthio-1H-tetrazole has also been prepared using DMF as solvent albeit in much lower yield.

General Description

5-(Ethylthio)-1H-tetrazole (ETT) is an efficient activator, that activates nucleoside phosphoramidites towards condensation with a nucleoside to form dinucleoside phosphates during oligonucleotide synthesis.

Purification Methods

recrystallized from toluene.

5-(Ethylthio)-1H-tetrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(Ethylthio)-1H-tetrazole Suppliers

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View Lastest Price from 5-(Ethylthio)-1H-tetrazole manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-(Ethylthio)-1H-tetrazole 89797-68-2
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-31
Hebei Duling International Trade Co. LTD
Product
5-(Ethylthio)-1H-tetrazole 89797-68-2
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100 tons
Release date
2022-10-09
Hebei Mojin Biotechnology Co., Ltd
Product
5-(Ethylthio)-1H-tetrazole 89797-68-2
Price
US $40.00/KG
Min. Order
25KG
Purity
99.99%
Supply Ability
20ton
Release date
2023-08-31

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