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ChemicalBook > CAS DataBase List > (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

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Product Name
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
CAS No.
112022-81-8
Chemical Name
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
Synonyms
(S)-2-METHYL-CBS-OXAZABOROLIDINE;(S)-1-METHYL-3,3-DIPHENYLHEXAHYDROPYRROLO[1,2-C][1,3,2]OXAZABOROLE;(S)-ME CBS;(S)-Me-CBS Catalyst;(S)-2-METHYL-CBS-OXAZABOROL;(S)-(-)-2-METHYL-CBS-OXAZABOROLIDINE;(s)-(-)-2-methyl-cbs-oxazaborolidine solution;(S)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE;(S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(S)-Methyloxazaborolidine;(s)-methyl
CBNumber
CB3106062
Molecular Formula
C18H20BNO
Formula Weight
277.17
MOL File
112022-81-8.mol
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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Property

Melting point:
115-117°C
Boiling point:
111 °C
Density 
0.93 g/mL at 20 °C(lit.)
refractive index 
-68 ° (C=1, MeOH)
Flash point:
40 °F
storage temp. 
room temp
form 
Liquid
pka
1.02±0.40(Predicted)
color 
Colorless to amber
Water Solubility 
Hydrolyzes in water.
Sensitive 
Air & Moisture Sensitive
BRN 
8492123
Exposure limits
ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3)
InChIKey
VMKAFJQFKBASMU-KRWDZBQOSA-N
CAS DataBase Reference
112022-81-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn,F
Risk Statements 
36/37/38-67-65-63-48/20-11-19-40
Safety Statements 
26-62-36/37-33-29-16
RIDADR 
UN 1294 3/PG 2
WGK Germany 
3
10-21
HazardClass 
3
PackingGroup 
II
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
457701
Product name
(S)-(?)-2-Methyl-CBS-oxazaborolidine solution
Purity
1 M in toluene
Packaging
5ml
Price
$98.6
Updated
2024/03/01
Sigma-Aldrich
Product number
457701
Product name
(S)-(?)-2-Methyl-CBS-oxazaborolidine solution
Purity
1 M in toluene
Packaging
25ml
Price
$345
Updated
2024/03/01
TCI Chemical
Product number
D2131
Product name
(S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine
Purity
>98.0%(T)
Packaging
1g
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
D2131
Product name
(S)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine
Purity
>98.0%(T)
Packaging
5g
Price
$331
Updated
2024/03/01
Alfa Aesar
Product number
L09219
Product name
(S)-2-Methyl-CBS-oxazaborolidine monohydrate, 94%
Packaging
1g
Price
$272
Updated
2021/12/16
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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Chemical Properties,Usage,Production

Reaction

  1. Convenient catalyst for the enantioselective borane reduction of ketones at ambient temperatures.
  2. Asymmetric synthesis of α-chiral hydroxyalkylphosphines via a catalytic, enantioselective reduction of acylphosphines.
  3. Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: Stereospecific formation of diarylalkanes and triarylmethanes.
  4. Enantioselective reduction of prochiral ketones with NaBH4/Me2SO4/(S)-Me-CBS.

Chemical Properties

Colorless to yellow liquid

Uses

(S)-2-Methyl-CBS-oxazaborolidine is used as an oxazaborolidine catalyst. It is also employed in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols and propargyl alcohols. It is an anhydrous catalyst for 'CBS' reduction reaction.

Uses

suzuki reaction

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Suppliers

Shanghai Forxine Pharmaceutical Co., Ltd.
Tel
21-21-64961388 18918697718
Fax
6496-1388-8320
Email
service@forxine.com
Country
China
ProdList
62
Advantage
60
Viwit Pharmaceutical Co., Ltd.
Tel
0632-0632-2980981 15063270987
Fax
0632-2989678
Email
service.china3@viwit.com
Country
China
ProdList
136
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
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View Lastest Price from (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole 112022-81-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
(S)-()-2-Methyl-CBS-oxazaborolidine solution 112022-81-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole 112022-81-8
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
as request
Release date
2018-12-23

112022-81-8, (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaboroleRelated Search:


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