Dihydrocapsaicin

Product Name: Dihydrocapsaicin
CAS No.: 19408-84-5
Chemical Name: Dihydrocapsaicin
Synonyms: CAPSAICINE;N-(3-Methoxy-4-hydroxybenzyl)-8-methylnonanamide;(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;FEMA 2787;FEMA 3404;CCRIS1589;(E)-CAPSAICIN;ihydrocapsaicin;Dihydrocapsaicin;CAPSAICIN, NATURAL
CBNumber: CB3112966
Molecular Formula: C18H29NO3
Formula Weight: 307.43
MOL File: 19408-84-5.mol

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Dihydrocapsaicin Property

Melting point:: 62-65 °C(lit.)
Boiling point:: 497.4±35.0 °C(Predicted)
Density: 1.026±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: H₂O: insoluble
form: White to off-white solid.
pka: 9.76±0.20(Predicted)
BRN: 2815150
InChIKey: XJQPQKLURWNAAH-UHFFFAOYSA-N
LogP: 3.556 (est)
CAS DataBase Reference: 19408-84-5(CAS DataBase Reference)
EPA Substance Registry System: Dihydrocapsaicin (19408-84-5)

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Safety

Hazard Codes: T
Risk Statements: 25-37/38-41-42/43-36/37/38
Safety Statements: 22-26-28-36/39-45-36/37/39
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: RA8530000
F: 10-21
HazardClass: 6.1(a)
PackingGroup: II
HS Code: 29399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2627
Product name: Dihydrocapsaicin
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50MG
Price: $267
Updated: 2024/03/01

Sigma-Aldrich

Product number: PHL89647
Product name: Dihydrocapsaicin
Purity: phyproof? Reference Substance
Packaging: 20MG
Price: $288
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1200600
Product name: Dihydrocapsaicin
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $741
Updated: 2024/03/01

Sigma-Aldrich

Product number: 03813
Product name: Dihydrocapsaicin
Purity: analytical standard
Packaging: 5mg
Price: $82.8
Updated: 2024/03/01

Cayman Chemical

Product number: 92355
Product name: Dihydrocapsaicin
Purity: ≥98%
Packaging: 5mg
Price: $32
Updated: 2024/03/01

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Dihydrocapsaicin Chemical Properties,Usage,Production

Description

Dihydrocapsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It is active against E. faecalis, B. subtilis, S. aureus, P. aeruginosa, K. pneumoniae, E. coli, and C. albicans (MICs = 0.6-10 μg/ml). Dihydrocapsaicin scavenges DPPH and ABTS radicals in cell-free assays. It increases LC3-II, a marker of autophagy, and catalase levels and reduces reactive oxygen species (ROS) production in normal WI38 lung fibroblasts and H1299, but not A549 or H460, lung cancer cells when used at a concentration of 200 μM. Dihydrocapsaicin is an agonist of transient receptor potential vanilloid 1 (TRPV1) and inhibits NETosis induced by phorbol 12-myristate 13-acetate (TPA; ) in isolated human neutrophils. It induces cortical and systemic hypothermia and reduces infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 0.5 mg/kg, i.p.

Chemical Properties

White Solid

Uses

Dihydrocapsaicin has been used as a reference standard for the identification of dihydrocapsaicin in blood and tissue samples by high performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS) and in tomato-based salsas by enzyme immunoassay (EIA) and LC with fluorescent detection.
It may be used as a reference standard for the determination of dihydrocapsaicin in Capsicum fruit samples by HPLC equipped with a Surveyor photodiode array (PDA) detector and in rat plasma by HPLC-triple quadrupole MS with electrospray ionization (ESI) in selected reaction monitoring (SRM) mode.

Uses

Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.

Definition

ChEBI: Dihydrocapsaicin is a capsaicinoid.

General Description

Dihydrocapsaicin belongs to the capsaicinoid group of compounds which are responsible for the pungency of capsicum fruits.

Biochem/physiol Actions

VR1 vanilloid receptor agonist.

Dihydrocapsaicin Preparation Products And Raw materials

Raw materials

Preparation Products

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Dihydrocapsaicin Suppliers

Canada 1 China 251 France 1 Germany 3 India 3 Japan 3 South Korea 1 Switzerland 4 United Kingdom 13 United States 44 USA 1 Global 325

Nanjing Duolong Bio-tech Co.,Ltd.

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Rhawn Reagent

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Shandong Xiya Chemical Co., Ltd

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View Lastest Price from Dihydrocapsaicin manufacturers

Sinoway Industrial co., ltd.

Product: Dihydrocapsaicin 19408-84-5
Price: US $0.00-0.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 98% up,
Supply Ability: 20 tons
Release date: 2024-06-27

BINBO BIOLOGICAL CO.,LTD

Product: Dihydrocapsaicin 19408-84-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99.8%
Supply Ability: 1000 kg
Release date: 2024-04-16

PNP Biotech Co. Ltd

Product: Dihydrocapsaicin 19408-84-5
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2022-10-25

19408-84-5, DihydrocapsaicinRelated Search:

Thiophanate-methyl Bensulfuron methyl Aluminum dihydrogen phosphate Ammonium dihydrogen phosphate METSULFURON METHYL Dipotassium hydrogen phosphate trihydrate (Trifluoromethoxy)benzene Anisole Methyl acetate Kresoxim-methyl Methylparaben Methyl acrylate DIHYDROCAPSAICIN(P) p-Anisidine p-Anisaldehyde Sodium phosphate dibasic dodecahydrate Taxifolin Methyl Capsaicine

CAPSAICINE

CAPSAICIN, NATURAL

(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE

(E)-CAPSAICIN

(E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE

FEMA 3404

FEMA 2787

N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6E-NONENAMIDE

N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE

TRANS-8-METHYL-N-VANILLYL-6-NONENAMIDE

6,7-dihydrocapsaicin

8-methyl-n-vanillyl-nonanamid

Dihydrocapsaicin, froM CapsicuM annuuM

N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonenamide

-8-methylnonanamide

N-(4-Hydroxy-3-methoxybenzyl)

Dihydrocapsaicin, 98%, from Capsicum annuum L.

8-METHYL-N-VANILLYL-TRANS-6-NONENAMIDE

8-METHYL-N-VANILLYL-6-NONENEAMIDE

Dihydro capsaicin - Natural extraction

Dihydro capsaicin - Synthetic

N-[(4-hydroxy-3-methoxy-1-cyclohexa-2,4-dienyl)methyl]-8-methyl-6-nonenamide

Dihydrocapsaicin, 98%, from Capsicum annuum

8-methyl-N-vanillylnonanamide approx.*90% from ca

8-METHYL-N-VANILLYLNONANAMIDE APPROX.*90 % FROM CAPS

DIHYDROCAPSAICIN, NATURAL

Dihydrocapsaicin std.

8-METHYL-N-VANILLYLNONANAMIDE 90+%

CAPSAICIN/8-METHYL-NONANOICACIDVANILLYLAMIDE

N-(3-Methoxy-4-hydroxybenzyl)-8-methylnonanamide

(E)-N-[(4-Hydroxy-3-methoxyphenyl)-8-methyl-6-nonenamide

Dihydrocapsaicin Standard

8-Methyl-N-vanillylnonanamide

Dihydrocapsaicin

N-(4-hydroxy-3-methoxy-benzyl)-8-methyl-pelargonamide

Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

N-(4-hydroxy-3-Methoxybenzyl)-8-MethylnonanaMide

Dihydrocapsaicin (25 mg)

CCRIS1589

Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-

ihydrocapsaicin

Dihydrocapsaicin USP/EP/BP

19408-84-5 Dihydrocapsaicin

Valine Impurity 77

19408-84-5

C18H29NO3

Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P.

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