ChemicalBook > CAS DataBase List > Dihydrocapsaicin

Dihydrocapsaicin

Product Name
Dihydrocapsaicin
CAS No.
19408-84-5
Chemical Name
Dihydrocapsaicin
Synonyms
CAPSAICINE;N-(3-Methoxy-4-hydroxybenzyl)-8-methylnonanamide;(E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE;FEMA 2787;FEMA 3404;CCRIS1589;(E)-CAPSAICIN;ihydrocapsaicin;Dihydrocapsaicin;CAPSAICIN, NATURAL
CBNumber
CB3112966
Molecular Formula
C18H29NO3
Formula Weight
307.43
MOL File
19408-84-5.mol
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Dihydrocapsaicin Property

Melting point:
62-65 °C(lit.)
Boiling point:
497.4±35.0 °C(Predicted)
Density 
1.026±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O: insoluble
form 
White to off-white solid.
pka
9.76±0.20(Predicted)
color 
White to off-white
BRN 
2815150
InChIKey
XJQPQKLURWNAAH-UHFFFAOYSA-N
LogP
3.556 (est)
CAS DataBase Reference
19408-84-5(CAS DataBase Reference)
EPA Substance Registry System
Dihydrocapsaicin (19408-84-5)
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Safety

Hazard Codes 
T
Risk Statements 
25-37/38-41-42/43-36/37/38
Safety Statements 
22-26-28-36/39-45-36/37/39
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
RA8530000
F 
10-21
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2627
Product name
Dihydrocapsaicin
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50MG
Price
$267
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL89647
Product name
Dihydrocapsaicin
Purity
phyproof? Reference Substance
Packaging
20MG
Price
$288
Updated
2024/03/01
Sigma-Aldrich
Product number
1200600
Product name
Dihydrocapsaicin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$741
Updated
2024/03/01
Sigma-Aldrich
Product number
03813
Product name
Dihydrocapsaicin
Purity
analytical standard
Packaging
5mg
Price
$82.8
Updated
2024/03/01
Cayman Chemical
Product number
92355
Product name
Dihydrocapsaicin
Purity
≥98%
Packaging
5mg
Price
$32
Updated
2024/03/01
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Dihydrocapsaicin Chemical Properties,Usage,Production

Description

Dihydrocapsaicin is a terpene alkaloid that has been found in Capsicum and has diverse biological activities. It is active against E. faecalis, B. subtilis, S. aureus, P. aeruginosa, K. pneumoniae, E. coli, and C. albicans (MICs = 0.6-10 μg/ml). Dihydrocapsaicin scavenges DPPH and ABTS radicals in cell-free assays. It increases LC3-II, a marker of autophagy, and catalase levels and reduces reactive oxygen species (ROS) production in normal WI38 lung fibroblasts and H1299, but not A549 or H460, lung cancer cells when used at a concentration of 200 μM. Dihydrocapsaicin is an agonist of transient receptor potential vanilloid 1 (TRPV1) and inhibits NETosis induced by phorbol 12-myristate 13-acetate (TPA; ) in isolated human neutrophils. It induces cortical and systemic hypothermia and reduces infarct volume in a rat model of ischemia-reperfusion injury induced by middle cerebral artery occlusion (MCAO) when administered at a dose of 0.5 mg/kg, i.p.

Chemical Properties

White Solid

Uses

Dihydrocapsaicin has been used as a reference standard for the identification of dihydrocapsaicin in blood and tissue samples by high performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS) and in tomato-based salsas by enzyme immunoassay (EIA) and LC with fluorescent detection.
It may be used as a reference standard for the determination of dihydrocapsaicin in Capsicum fruit samples by HPLC equipped with a Surveyor photodiode array (PDA) detector and in rat plasma by HPLC-triple quadrupole MS with electrospray ionization (ESI) in selected reaction monitoring (SRM) mode.

Uses

Capsaicin (C175680) analog. A VR1 vaniloid receptor agonist.

Definition

ChEBI: Dihydrocapsaicin is a capsaicinoid.

General Description

Dihydrocapsaicin belongs to the capsaicinoid group of compounds which are responsible for the pungency of capsicum fruits.

Biochem/physiol Actions

VR1 vanilloid receptor agonist.

Dihydrocapsaicin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Dihydrocapsaicin manufacturers

Sinoway Industrial co., ltd.
Product
Dihydrocapsaicin 19408-84-5
Price
US $0.00-0.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
98% up,
Supply Ability
20 tons
Release date
2024-06-27
BINBO BIOLOGICAL CO.,LTD
Product
Dihydrocapsaicin 19408-84-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
1000 kg
Release date
2024-04-16
PNP Biotech Co. Ltd
Product
Dihydrocapsaicin 19408-84-5
Price
US $0.00/kg
Min. Order
25kg
Purity
98%
Supply Ability
Inquiry
Release date
2022-10-25

19408-84-5, DihydrocapsaicinRelated Search:

Thiophanate-methyl Bensulfuron methyl Aluminum dihydrogen phosphate Ammonium dihydrogen phosphate METSULFURON METHYL Dipotassium hydrogen phosphate trihydrate (Trifluoromethoxy)benzene Anisole Methyl acetate Kresoxim-methyl Methylparaben Methyl acrylate DIHYDROCAPSAICIN(P) p-Anisidine p-Anisaldehyde Sodium phosphate dibasic dodecahydrate Taxifolin Methyl Capsaicine

  • CAPSAICINE
  • CAPSAICIN, NATURAL
  • (E)-8-METHYL-NON-6-ENOIC ACID 4-HYDROXY-3-METHOXY-BENZYLAMIDE
  • (E)-CAPSAICIN
  • (E)-N-([4-HYDROXY-3-METHOXYPHENYL]METHYL)8-METHYL-6-NONEAMIDE
  • FEMA 3404
  • FEMA 2787
  • N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6E-NONENAMIDE
  • N-[(4-HYDROXY-3-METHOXYPHENYL)METHYL]-8-METHYL-6-NONENAMIDE
  • TRANS-8-METHYL-N-VANILLYL-6-NONENAMIDE
  • 6,7-dihydrocapsaicin
  • 8-methyl-n-vanillyl-nonanamid
  • Dihydrocapsaicin, froM CapsicuM annuuM
  • N-[(4-Hydroxy-3-methoxyphenyl)methyl]-8-methylnonenamide
  • -8-methylnonanamide
  • N-(4-Hydroxy-3-methoxybenzyl)
  • Dihydrocapsaicin, 98%, from Capsicum annuum L.
  • 8-METHYL-N-VANILLYL-TRANS-6-NONENAMIDE
  • 8-METHYL-N-VANILLYL-6-NONENEAMIDE
  • Dihydro capsaicin - Natural extraction
  • Dihydro capsaicin - Synthetic
  • N-[(4-hydroxy-3-methoxy-1-cyclohexa-2,4-dienyl)methyl]-8-methyl-6-nonenamide
  • Dihydrocapsaicin, 98%, from Capsicum annuum
  • 8-methyl-N-vanillylnonanamide approx.*90% from ca
  • 8-METHYL-N-VANILLYLNONANAMIDE APPROX.*90 % FROM CAPS
  • DIHYDROCAPSAICIN, NATURAL
  • Dihydrocapsaicin std.
  • 8-METHYL-N-VANILLYLNONANAMIDE 90+%
  • CAPSAICIN/8-METHYL-NONANOICACIDVANILLYLAMIDE
  • N-(3-Methoxy-4-hydroxybenzyl)-8-methylnonanamide
  • (E)-N-[(4-Hydroxy-3-methoxyphenyl)-8-methyl-6-nonenamide
  • Dihydrocapsaicin Standard
  • 8-Methyl-N-vanillylnonanamide
  • Dihydrocapsaicin
  • N-(4-hydroxy-3-methoxy-benzyl)-8-methyl-pelargonamide
  • Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
  • N-(4-hydroxy-3-Methoxybenzyl)-8-MethylnonanaMide
  • Dihydrocapsaicin (25 mg)
  • CCRIS1589
  • Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-
  • ihydrocapsaicin
  • Dihydrocapsaicin USP/EP/BP
  • 19408-84-5 Dihydrocapsaicin
  • Valine Impurity 77
  • DIHYDROCAPSAICIN(P) 10mg
  • Dihydrocapsaicin-RM
  • Dihydrocapsaicin in Methanol
  • 19408-84-5
  • C18H29NO3
  • Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P.
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