2-Biphenylcarboxylic acid
- Product Name
- 2-Biphenylcarboxylic acid
- CAS No.
- 947-84-2
- Chemical Name
- 2-Biphenylcarboxylic acid
- Synonyms
- carboxyL;2-BiphenyL;BIPHENYL-2-CARBOXYLIC ACID;2-PHENYLBENZOIC ACID;Ortho-phenyl benzoic acid;[1,1'-Biphenyl]-2-carboxylic acid;-[(1,4’Conivaptan-1;-Bipiperidine;2-benzoic acid
- CBNumber
- CB3114894
- Molecular Formula
- C13H10O2
- Formula Weight
- 198.22
- MOL File
- 947-84-2.mol
2-Biphenylcarboxylic acid Property
- Melting point:
- 111-113 °C(lit.)
- Boiling point:
- 199 °C10 mm Hg(lit.)
- Density
- 1.1184 (rough estimate)
- refractive index
- 1.5954 (estimate)
- Flash point:
- 343-344°C
- storage temp.
- Sealed in dry,Room Temperature
- form
- Crystalline Powder
- pka
- 3.46(at 25℃)
- color
- White to beige
- Water Solubility
- insoluble
- BRN
- 974075
- InChIKey
- ILYSAKHOYBPSPC-UHFFFAOYSA-N
- CAS DataBase Reference
- 947-84-2(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Biphenylcarboxylic acid(947-84-2)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39-37
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29163900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B34702
- Product name
- Biphenyl-2-carboxylic acid
- Purity
- 98%
- Packaging
- 25g
- Price
- $73.8
- Updated
- 2023/06/20
- Product number
- B34702
- Product name
- Biphenyl-2-carboxylic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $44.6
- Updated
- 2023/01/07
- Product number
- P0906
- Product name
- Biphenyl-2-carboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $99
- Updated
- 2024/03/01
- Product number
- P0906
- Product name
- Biphenyl-2-carboxylic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 100g
- Price
- $279
- Updated
- 2024/03/01
- Product number
- A12049
- Product name
- Biphenyl-2-carboxylic acid, 98%
- Packaging
- 5g
- Price
- $20.65
- Updated
- 2024/03/01
2-Biphenylcarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
2-Biphenylcarboxylic acid is White powder
Uses
2-Biphenylcarboxylic acid is used in the preparation of neuropeptide FF receptor antagonists. In addition it is used in the synthesis of disubstituted piperidines as orexin receptor antagonists.
Uses
It is used as a pharmaceutical intermediate. he reaction of 2?-substituted biphenyl-2-carboxylic acids (where the 2?-substituent is H, CO2H, NO2, Cl, OMe, or CO2Me) with lead tetra-acetate in refluxing benzene solution, under a nitrogen atmosphere, affords 3,4-benzocoumarin as a major organic product.
Synthesis Reference(s)
The Journal of Organic Chemistry, 43, p. 447, 1978 DOI: 10.1021/jo00397a015
Purification Methods
Crystallise the acid from *C6H6/pet ether or aqueous EtOH. [Beilstein 9 IV 2472.]
2-Biphenylcarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Biphenylcarboxylic acid manufacturers
- Product
- 2-Biphenylcarboxylic acid 947-84-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 10mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-15
- Product
- 2-Phenylbenzoic acid 947-84-2
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.0%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21
- Product
- 2-Biphenylcarboxylic acid 947-84-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26