Tenidap

Product Name: Tenidap
CAS No.: 120210-48-2
Chemical Name: Tenidap
Synonyms: TENIDAP;AKOS 91367;TENIDAP USP/EP/BP;CP66248,CP-66248-2;5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide;(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide;(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide;1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-
CBNumber: CB3121977
Molecular Formula: C14H9ClN2O3S
Formula Weight: 320.75
MOL File: 120210-48-2.mol

More

Less

Tenidap Property

Melting point:: 230° (dec)
Boiling point:: 538.1±60.0 °C(Predicted)
Density: 1.648±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: DMSO: soluble1mg/mL, clear (warmed)
form: powder
pka: 4.50±1.00(Predicted)
color: faint yellow to dark yellow

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0196
Product name: Tenidap
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $129
Updated: 2024/03/01

Sigma-Aldrich

Product number: PZ0196
Product name: Tenidap
Purity: ≥97% (HPLC)
Packaging: 25mg
Price: $401
Updated: 2024/03/01

Cayman Chemical

Product number: 17413
Product name: Tenidap
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17413
Product name: Tenidap
Purity: ≥98%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 17413
Product name: Tenidap
Purity: ≥98%
Packaging: 10mg
Price: $122
Updated: 2024/03/01

More

Less

Tenidap Chemical Properties,Usage,Production

Uses

Anti-inflammatory (osteoarthritis and rheumatoid arthritis).

Uses

Tenidap is one of the nonsteroidal antiinflammatory drugs (NSAIDs). Tenidap is an NSAID that preferentially inhibits COX-1. Tenidap inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes.

Definition

ChEBI: Tenidap is a member of indoles, a member of ureas, a member of thiophenes and an organochlorine compound. It has a role as a non-steroidal anti-inflammatory drug and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor.

Biological Activity

NSAID that preferentially inhibits COX-1 (IC 50 values are < 0.03, 1.2 and > 30 μ M for COX-1, COX-2 and 5-lipoxygenase respectively). Inhibits formation of pro-inflammatory arachidonic acid metabolites in isolated human peripheral polymorphonuclear leukocytes. Opener of inward rectifying hK IR 2.3 channel (EC 50 = 402 nM).

storage

Store at +4°C

Mode of action

Tenidap is an anti-inflammatory agent developed by Pfizer with a unique structure that is different and distinguishable from NSAIDs. The mechanism of action of tenidap is that it has dual inhibitory effects on lipoxygenase and dioxygenase, and has antagonism on interleukin-1 (IL-1).

Tenidap Preparation Products And Raw materials

Raw materials

Formyl chloride Chloral hydrate 4-Methylmorpholine Ethanol Methyl chloroformate Sodium bicarbonate Hydroxylamine hydrochloride 4-Chloroaniline

Preparation Products

More

Less

Tenidap Suppliers

China 48 Europe 3 Germany 2 India 1 United Kingdom 4 United States 13 Global 71

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52924
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

MedChemExpress

Tel: --
Fax: --
Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Fine Chem Trading LTD

Tel: --
Fax: --
Email: chemfinder@chemfinder.co.uk
Country: United States
ProdList: 1609
Advantage: 64

More

Less

View Lastest Price from Tenidap manufacturers

Dideu Industries Group Limited

Product: TENIDAP 120210-48-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-06

120210-48-2, TenidapRelated Search:

Delgocitinib Coenzyme Q10 Metadoxine Feprazone Ibrutinib Diclofenac sodium

TENIDAP

AKOS 91367

5-Chloro-2，3-dihydro-2-oxo-3-(2-thenoyl)-1H-indole-1-carboxamide

CP66248,CP-66248-2

(3Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H-indole-1-carboxaMide

(Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylMethylene)-2-oxo-1H- indole-1-carboxaMide

1H-Indole-1-carboxamide, 5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-, (3Z)-

TENIDAP USP/EP/BP

120210-48-2

C14H9N2O3SCl