N-methylisatoic anhydride

Product Name: N-methylisatoic anhydride
CAS No.: 10328-92-4
Chemical Name: N-methylisatoic anhydride
Synonyms: MIA;NSC439;NSC 439;NSC-439;AKOS 226;AI300638;NSC 76087;MIA human;4-dithiin;AI3 00638
CBNumber: CB3126220
Molecular Formula: C9H7NO3
Formula Weight: 177.16
MOL File: 10328-92-4.mol

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N-methylisatoic anhydride Property

Melting point:: 165 °C (dec.)(lit.)
Boiling point:: 309.06°C (rough estimate)
Density: 1.3312 (rough estimate)
vapor density: 6.1 (vs air)
refractive index: 1.5200 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: Soluble in DMSO
form: Solid
pka: -2.24±0.20(Predicted)
color: White to yellow
Sensitive: Moisture Sensitive
CAS DataBase Reference: 10328-92-4(CAS DataBase Reference)
EPA Substance Registry System: 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl- (10328-92-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
RTECS: DM3140000
TSCA: Yes
HS Code: 2934.99.4400

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 129887
Product name: N-Methylisatoic anhydride
Purity: technical, 90%
Packaging: 100g
Price: $89.2
Updated: 2024/03/01

TCI Chemical

Product number: M0743
Product name: N-Methylisatoic Anhydride
Packaging: 5G
Price: $102
Updated: 2024/03/01

TCI Chemical

Product number: M0743
Product name: N-Methylisatoic Anhydride
Purity: >98.0%(GC)
Packaging: 25g
Price: $400
Updated: 2024/03/01

Alfa Aesar

Product number: B24099
Product name: N-Methylisatoic anhydride, tech. 90%
Packaging: 100g
Price: $58.65
Updated: 2024/03/01

TRC

Product number: M293158
Product name: 1-Methyl-1H-benzo[d][1,3]oxazine-2,4-dione
Packaging: 500mg
Price: $55
Updated: 2021/12/16

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N-methylisatoic anhydride Chemical Properties,Usage,Production

Chemical Properties

brownish chunks

Uses

N-Methylisatoic anhydride is a 2'-OH selective acylation agent of RNAs, and is widely used for resolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology.

Definition

ChEBI: N-methylisatoic anhydride is a 3,1-benzoxazin-1,4-dione having an N-methyl substituent.

Application

N-Methylisatoic anhydride was first condensed with ethanolamine to give N-(2-hydroxyethyl)-2-methylaminobenzamide. Cyclization of the latter with ethyl pyruvate gave quinazoline derivatives which, upon hydrolysis and dehydrative cyclization with l-methyl-2-chloropyridinium iodide, afforded the l,4-oxazines[3,4-]quinazoline.

N-methylisatoic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-methylisatoic anhydride manufacturers

Shanghai Rlavie Technology Co ltd

Product: N-Methylisatoic anhydride 10328-92-4
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 500kgs/month
Release date: 2021-11-14

Career Henan Chemical Co

Product: N-METHYLISATOIC ANHYDRIDE 10328-92-4
Price: US $100.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-07-25

Career Henan Chemical Co

Product: N-METHYLISATOIC ANHYDRIDE 10328-92-4
Price: US $20.00/KG
Min. Order: 1KG
Purity: 995
Supply Ability: 20kg
Release date: 2018-07-30

10328-92-4, N-methylisatoic anhydrideRelated Search:

5-Chloro-N-methylisatoic anhydride N-methylisatoic anhydride Ethyl 4-dimethylaminobenzoate Isatoic Anhydride 1-ISOPROPYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE N-BENZYLISATOIC ANHYDRIDE 5-CHLORO-1-METHYL-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE 3-METHOXY-N-METHYLISATOIC ANHYDRIDE N-ALLYLISATOIC ANHYDRIDE 6-Methylisatoic anhydride 5-METHYLISATOIC ANHYDRIDE 7-FLUORO-2-METHYLISATOIC ANHYDRIDE AMILORIDE, 5-(N-METHYL-N-ISOBUTYL) (MIA) >97% EXTREMELY POTE,MIA 6-CHLORO-N-METHYLISATOIC ANHYDRIDE N-METHYLISATOIC ANHYDRIDE POLYSTYRENE (100-200 MESH, 3 MMOL/G) HUMAN MIA KG POA 5-METHYLISATOIC ANHYDRIDE MIA protein

N-methyl isotoic anhydride

Isatoic anhydride, N-Methyl-

N-Methylisatioc anhydride

1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

1-Methyl-1,2-dihydro-4H-3,1-benzoxazine-2,4-dione

1-Methyl-1H-3,1-benzoxazine-2,4-dione

1-Methyl-4H-3,1-benzoxazine-2(1H),4-dione

N-Methylisatoic anhydride,90%,tech.

N-Methylisatoic anhydride (NMIA)

1-methyl-3,1-benzoxazine-2,4-dione

<i>N</i>-Methylisatoic Anhydride

MIA

N-METHYLISATOIC ANHYDRIDE

TIMTEC-BB SBB000196

1-Methyl-2H-3,1-benzoxazine-2,4(1H)-dione

2H-3,1-Benzoxazine-2,4(1H)-dione, 1-methyl-

4(1h)-dione,1-methyl-2h-1-benzoxazine-2

N-Methyl ia

n-methylia

N-Methyl-N-carboxyanthranilic anhydride

N-METHYLISATOIC ANHYDRIDE, TECH., 90%

N-Methylisatoicanhydride,tech.,90%

AKOS 226

1-Methyl-4H-3,1-benzoxazine-2,4(1H)dione

N-Methylisatoic acid anhydride

NSC 76087

N-Methylisatoic anhydride technical, 90%

Melanoma-derived growth regulatory protein precursor

MIA human

N-MethylisatoicAnhydride&gt

10-Dithiaanthracene

4-dithiin

AI3 00638

AI300638

AI3-00638

dibenzo-1

NSC 439

NSC439

NSC-439

10328-92-4

10328-92-7

Monomers

Polymer Science

pharmacetical

Anhydride Monomers