1-Phenylcyclobutanecarboxylic acid

Product Name: 1-Phenylcyclobutanecarboxylic acid
CAS No.: 37828-19-6
Chemical Name: 1-Phenylcyclobutanecarboxylic acid
Synonyms: 1-Phenylcyclobutanecarboxylic acid;Phenylcyclobutane-1-carboxylic acid;Cyclobutanecarboxylic acid, 1-phenyl-;2-phenyl-1-cyclobutanecarboxylic acid
CBNumber: CB31263487
Molecular Formula: C11H12O2
Formula Weight: 176.21
MOL File: 37828-19-6.mol

More

Less

1-Phenylcyclobutanecarboxylic acid Property

Melting point:: 100-102℃
Boiling point:: 323.9±21.0 °C(Predicted)
Density: 1.208±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder
pka: 4.39±0.20(Predicted)
color: White

More

Less

Safety

HS Code: 2916200090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P336618
Product name: 1-PhenylcyclobutanecarboxylicAcid
Packaging: 100mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: J55188
Product name: 1-Phenylcyclobutanecarboxylicacid
Packaging: 10g
Price: $450
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014834
Product name: PHENYLCYCLOBUTANE-1-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 1G
Price: $721.57
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014834
Product name: PHENYLCYCLOBUTANE-1-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 2.5G
Price: $983.88
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0014834
Product name: PHENYLCYCLOBUTANE-1-CARBOXYLIC ACID
Purity: 95.00%
Packaging: 5G
Price: $1168.42
Updated: 2021/12/16

More

Less

1-Phenylcyclobutanecarboxylic acid Chemical Properties,Usage,Production

Synthesis

14377-68-5

37828-19-6

Part A. 1-Phenyl-1-cyclobutanecarbonitrile (5.0 g, 31.83 mmol) and potassium hydroxide (85%, 6.29 g, 95.49 mmol, 3 eq.) were dissolved in ethylene glycol (10 mL) and the reaction was heated for 6 h at 185-190 °C under nitrogen protection. The completion of the reaction was monitored by LC-MS. The reaction mixture was cooled and diluted with the addition of water. The mixture was extracted with ether (3 x 10 mL). The aqueous layer was acidified with concentrated hydrochloric acid to pH < 2 and subsequently extracted with chloroform (2 x 10 mL). The chloroform layers were combined, washed sequentially with water and saturated saline, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 1-phenyl-1-cyclobutanecarboxylic acid (4.43 g, yield 79.2%). lC-MS (ESI+) m/z: 177.4 [M+H]+, retention time tR = 2.56 min (mobile phase: 10-90% acetonitrile/water, run time 6 min) .

References

[1] Chemische Berichte, 1984, vol. 117, # 11, p. 3303 - 3319
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 18, p. 7341 - 7348
[3] Patent: WO2003/99276, 2003, A1. Location in patent: Page 316-317
[4] Journal of Organometallic Chemistry, 1993, vol. 448, # 1-2, p. 9 - 14
[5] Pharmaceutical Chemistry Journal, 1980, vol. 14, # 2, p. 114 - 118

1-Phenylcyclobutanecarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-Phenylcyclobutanecarboxylic acid Suppliers

China 77 India 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 11 Global 93

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

More

Less

View Lastest Price from 1-Phenylcyclobutanecarboxylic acid manufacturers

Career Henan Chemical Co

Product: 1-Phenylcyclobutanecarboxylic acid 37828-19-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-25

37828-19-6, 1-Phenylcyclobutanecarboxylic acidRelated Search:

tert-Butylchlorodiphenylsilane Methyl 4-tert-butylbenzoate tert-Butyl methyl ether Methyl perfluoroisobutyl ether 4-tert-Butyltoluene Cyclobutanecarboxylic acid Glycine Pinacolone Benzoic acid DIPHENYLCYCLOPROPENONE Ethyl 2-(Chlorosulfonyl)acetate Retinoic acid Cyclopropanecarboxylic acid Folic acid Citric acid 1-(4-CHLOROPHENYL)-1-CYCLOBUTANECARBOXYLIC ACID Phenylacetone Propiophenone

Phenylcyclobutane-1-carboxylic acid

1-Phenylcyclobutanecarboxylic acid

2-phenyl-1-cyclobutanecarboxylic acid

Cyclobutanecarboxylic acid, 1-phenyl-

37828-19-6

Carboxylic Acids

Phenyls & Phenyl-Het

API intermediates

Acids and Derivatives