Adenanthin

Product Name: Adenanthin
CAS No.: 111917-59-0
Chemical Name: Adenanthin
Synonyms: Adenanthin;Actinodephnine Acuminatin Acuminatoside Adenanthin;Kaur-16-ene-6,15-dione, 1,7,11-tris(acetyloxy)-3-hydroxy-, (1α,3β,7β,11β)-;Kaur-16-ene-6,15-dione,1,7,11-tris(acetyloxy)-3-hydroxy-, (1a,3b,7b,11b)- (9CI)
CBNumber: CB31267733
Molecular Formula: C26H34O9
Formula Weight: 490.55
MOL File: 111917-59-0.mol

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Adenanthin Property

Boiling point:: 593.4±50.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
pka: 14.13±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN99215
Product name: Adenanthin
Packaging: 5mg
Price: $498
Updated: 2021/12/16

Crysdot

Product number: CD32002839
Product name: Adenanthin
Purity: 97%
Packaging: 5mg
Price: $930
Updated: 2021/12/16

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Adenanthin Chemical Properties,Usage,Production

Enzyme inhibitor

This diterpenoid (FW = 484.63 g/mol; CAS 111917-59-0) from the leaves of Rabdosia adenantha, induces differentiation of acute promyelocytic leukemia (APL) cells. Adenanthin targets the conserved cysteine thiols of peroxiredoxins I and II (or Prx I and Prx II), inhibiting their peroxidase activities and consequently increasing cellular hydrogen peroxide. The latter leads to the activation of Extracellular signal-Regulated Kinases (ERKs) and increased transcription of CCAAT/enhancer-binding protein β (or C/EBPs), further contributing to differentiation. Adenanthin induces APL-like cell differentiation, represses tumor growth in vivo and prolongs the survival of mouse APL models that are sensitive and resistant to retinoic acid.

Adenanthin Preparation Products And Raw materials

Raw materials

Preparation Products

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Adenanthin Suppliers

China 57 United States 5 Global 62

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

NE Scientific

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Country: United States
ProdList: 5030
Advantage: 55

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Adenanthin

Actinodephnine Acuminatin Acuminatoside Adenanthin

Kaur-16-ene-6,15-dione,1,7,11-tris(acetyloxy)-3-hydroxy-, (1a,3b,7b,11b)- (9CI)

Kaur-16-ene-6,15-dione, 1,7,11-tris(acetyloxy)-3-hydroxy-, (1α,3β,7β,11β)-

111917-59-0