ChemicalBook > CAS DataBase List > asebogenin
asebogenin
- Product Name
- asebogenin
- CAS No.
- 520-42-3
- Chemical Name
- asebogenin
- Synonyms
- asebogenin;4'-O-Methylphloretin;Dihydroisosakuranetin;Asebogenin, 10 mM in DMSO;1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-1-propanone;1-Propanone, 1-(2,6-dihydroxy-4-methoxyphenyl)-3-(4-hydroxyphenyl)-
- CBNumber
- CB31308236
- Molecular Formula
- C16H16O5
- Formula Weight
- 288.3
- MOL File
- 520-42-3.mol
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asebogenin Property
- Melting point:
- 168℃
- Boiling point:
- 550.9±50.0 °C(Predicted)
- Density
- 1.325±0.06 g/cm3(Predicted)
- pka
- 7.00±0.40(Predicted)
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N-Bromosuccinimide Price
Crysdot
- Product number
- CD32001126
- Product name
- Asebogenin
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $723
- Updated
- 2021/12/16
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asebogenin Chemical Properties,Usage,Production
Uses
Asebogenin has antimalarial activity in vitro[1]. Asebogenin can inhibit the phosphorylation of Syk, thereby effectively suppressing platelet activation and the formation of neutrophil extracellular traps[2].
Definition
ChEBI: A member of the class of dihydrochalcones that is the 4'-methyl ether derivative of phloretin.
References
[1] 1.Jenett-Siems K, et al. n vitro antiplasmodial activity of Central American medicinal plants. Trop Med Int Health. 1999 Sep;4(9):611-5. DOI:10.1046/j.1365-3156.1999.00456.x
[2] Li L, et al. Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation. Br J Pharmacol. 2023 Feb;180(3):287-307. DOI:10.1111/bph.15964
asebogenin Preparation Products And Raw materials
Raw materials
Preparation Products
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