ChemicalBook > CAS DataBase List > Sodium chlorodifluoroacetate

Sodium chlorodifluoroacetate

Product Name
Sodium chlorodifluoroacetate
CAS No.
1895-39-2
Chemical Name
Sodium chlorodifluoroacetate
Synonyms
Sodium 2-chloro-2,2-difluoroacetate;2-chloro-2,2-difluoroacetate;SodiuM Difluorochloroacetate;CHLORODIFLUOROACETIC ACID SODIUM SALT;DIFLUOROCHLOROACETIC ACID SODIUM SALT;orodifL;Roflumilast impurity 24;SODIUM CHLORODIFLUOROACETATE;CHLORODIFLUOROACETIC ACID, NA;Sodiumchlorodifluoroacetate97%
CBNumber
CB3135211
Molecular Formula
C2H2ClF2NaO2
Formula Weight
154.47
MOL File
1895-39-2.mol
More
Less

Sodium chlorodifluoroacetate Property

Melting point:
196-198 °C (lit.)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in dimethoxyethane, diglyme (0.60 g mL-1), triglyme, dimethyl formamide.
form 
Powder
color 
White to off-white
BRN 
4162363
InChIKey
MRTAVLDNYYEJHK-UHFFFAOYSA-M
CAS DataBase Reference
1895-39-2(CAS DataBase Reference)
EPA Substance Registry System
Acetic acid, chlorodifluoro-, sodium salt (1895-39-2)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25-36/37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
T
HazardClass 
IRRITANT, HYGROSCOPIC
HS Code 
29159080
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
374067
Product name
Sodium chlorodifluoroacetate
Purity
96%
Packaging
25g
Price
$88.1
Updated
2024/03/01
TCI Chemical
Product number
C0991
Product name
Sodium Chlorodifluoroacetate
Purity
>99.0%(T)
Packaging
25g
Price
$29
Updated
2024/03/01
TCI Chemical
Product number
C0991
Product name
Sodium Chlorodifluoroacetate
Purity
>99.0%(T)
Packaging
100g
Price
$82
Updated
2024/03/01
Alfa Aesar
Product number
A15756
Product name
Sodium chlorodifluoroacetate, 97%
Packaging
25g
Price
$79.2
Updated
2024/03/01
Alfa Aesar
Product number
A15756
Product name
Sodium chlorodifluoroacetate, 97%
Packaging
100g
Price
$196.65
Updated
2024/03/01
More
Less

Sodium chlorodifluoroacetate Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

It is used as pharmaceutical intermediate. Reactions of aldehydes with triphenylphosphine and sodium chlorodifluoroacetate yield 1,1-difluoro olefins. It is a general reaction and a one step synthesis.

Application

Sodium chlorodifluoroacetate is used for generation of difluorocarbene and the synthesis of difluorocyclopropanes and difluoroalkenes.

Preparation

Sodium chlorodifluoroacetate is prepared by careful neutralization of 130.5 g (1.0 mol) of chlorodifluoroacetic acid in 300 mL of Et2O with 53 g (0.5 mol) of anhydrous Na2CO3. The Et2O and water are removed under reduced pressure. The salt is then dried in a vacuum desiccator over P2O5. [1]

storage

Sodium chlorodifluoroacetate is an irritant and is hygroscopic.

References

1. Herkes, F. E.; Burton, D. J. OSC 1973, 5, 949

Sodium chlorodifluoroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Sodium chlorodifluoroacetate Suppliers

Americas 1 Belgium 2 Canada 1 China 255 Europe 3 France 1 Germany 4 India 8 Japan 4 Jordan 1 Switzerland 2 United Kingdom 16 United States 32 Global 330
Ji'nan Langhua Chemical Co. Ltd.
Tel
0531-85906691 18660816586
Fax
+86-0531-85906692
Email
325912680@qq.com
Country
China
ProdList
100
Advantage
50
HuBei ZhuoXi Fluorochemical Co., Ltd.,
Tel
0712-3586991 13801737011
Fax
0712-3586998
Email
xxg@hbzxchem.com
Country
China
ProdList
9
Advantage
58
Shanghai Furui Fine Chemicals Co., Ltd.
Tel
021-36041048 13361903612
Fax
86-021-36041048
Email
13361903612@189.cn
Country
China
ProdList
12
Advantage
55
chengqiaotech.ltd
Tel
18105338618
Email
zbcqyh@126.com
Country
China
ProdList
295
Advantage
58
Fuxin Kaituo Fine Chemical Technology Co., Ltd
Tel
15714082442
Email
3757845877@qq.com
Country
China
ProdList
346
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12386
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9510
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
HANGZHOU HETE CHEMICAL TECHNOLOGY CO.,LTD
Tel
571-89189769 15168342188
Fax
0571-86205065
Country
China
ProdList
253
Advantage
62
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4554
Advantage
62
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4001
Advantage
55
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1541
Advantage
55
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.
Tel
0523-82837785 13914525028
Fax
0523-87913272
Email
info@jszchg.com
Country
China
ProdList
249
Advantage
60
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6134
Advantage
55
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9478
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3930
Advantage
58
ShangHai Zexin Chemical Technology Co., Ltd.
Tel
021-60136491 15901897992
Fax
021-60136492
Country
China
ProdList
455
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Zhengzhou ALFA Chemical Co., Ltd.
Tel
0371-53732842 15981811963
Fax
0371-86239377
Email
1758257485@qq.com
Country
China
ProdList
950
Advantage
56
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9349
Advantage
58
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1686
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
SHANG FLUORO
Tel
021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
375
Advantage
60
More
Less

View Lastest Price from Sodium chlorodifluoroacetate manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Sodium chlorodifluoroacetate 1895-39-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-30
Hebei Weibang Biotechnology Co., Ltd
Product
Sodium chlorodifluoroacetate 1895-39-2
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-26
Zibo Hangyu Biotechnology Development Co., Ltd
Product
Sodium chlorodifluoroacetate 1895-39-2
Price
US $75.00-750.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-08

1895-39-2, Sodium chlorodifluoroacetateRelated Search:

Dichloroacetyl chloride Sodium bicarbonate Sodium chlorite Sodium fluorosilicate Trisodium hexafluoroaluminate Sodium chloroacetate Sodium chloride Sodium hydroxide Sodium citrate Sodium benzoate Diclofenac sodium Sodium acetate Chlorodifluoroacetic acid Trisodium phosphate Difluoroacetic acid 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT Ethyl bromodifluoroacetate METHYL DIFLUOROACETATE

  • DIFLUOROCHLOROACETIC ACID SODIUM SALT
  • CHLORODIFLUOROACETIC ACID, NA
  • CHLORODIFLUOROACETIC ACID SODIUM
  • CHLORODIFLUOROACETIC ACID SODIUM SALT
  • chlorodifluoro-aceticacisodiumsalt
  • SODIUM CHLORODIFLUOROACETATE
  • Sodium chlorodifluoroacetate 97%
  • Sodiumchlorodifluoroacetate97%
  • Acetic acid, chlorodifluoro-, sodium salt
  • Sodium 2-chloro-2,2-difluoroacetate
  • Chlorodifluoroacetic acid sodium salt,96%
  • Chlorodifluoroacetic acid sodium salt 5g [1895-39-2]
  • Sodium chlorodifluoroacetate,Chlorodifluoroacetic acid sodium salt
  • Chlorodifluoroacetic acid sodiuM salt, 96% 25GR
  • 2-Chloro-2,2-difluoro-acetic Acid SodiuM Salt
  • SodiuM Difluorochloroacetate
  • Sodium 2-chloro-2,2-difluoroethanoate, Chloro(difluoro)acetic acid, sodium salt
  • Two fluorinesodiuM chloroacetate
  • Acetic acid,2-chloro-2,2-difluoro-, sodiuM salt (1:1)
  • orodifL
  • Roflumilast impurity 24
  • Sodium Chlorodifluoroacetate &gt
  • 2-chloro-2,2-difluoroacetate
  • 1895-39-2
  • 1985-39-2
  • C2ClFNaO2
  • ClCF2CO2Na
  • C2ClF2NaO2
  • C2ClF2O2Na
  • Inorganic Salts
  • Synthetic Reagents
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Miscellaneous Reagents
  • Pharmaceutical Intermediates
  • Fluorinated Building Blocks
  • Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
  • Synthetic Organic Chemistry