ChemicalBook > CAS DataBase List > Bromisoval

Bromisoval

Product Name
Bromisoval
CAS No.
496-67-3
Chemical Name
Bromisoval
Synonyms
BVU;Alural;B.V.U.;Bromyl;Abroval;Alluval;Somnurol;Bromaral;Bromoval;Bromoxil
CBNumber
CB3138005
Molecular Formula
C6H11BrN2O2
Formula Weight
223.07
MOL File
496-67-3.mol
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Bromisoval Property

Melting point:
152 °C
Density 
1.6005 (rough estimate)
refractive index 
1.5410 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.54±0.70(Predicted)
color 
White to Off-White
Water Solubility 
19.03g/L(temperature not stated)
Merck 
14,1397
InChIKey
CMCCHHWTTBEZNM-UHFFFAOYSA-N
CAS DataBase Reference
496-67-3(CAS DataBase Reference)
NIST Chemistry Reference
Bromisovalum(496-67-3)
EPA Substance Registry System
Butanamide, N-(aminocarbonyl)-2-bromo-3-methyl- (496-67-3)
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Safety

RTECS 
YS3150000
HS Code 
2924.19.8000
Toxicity
LD50 in male mice (mmoles/kg): 3.25 i.p. (Mrongovius)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
B2842
Product name
1-(2-Bromoisovaleryl)urea
Purity
>98.0%(T)
Packaging
25g
Price
$109
Updated
2024/03/01
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
100g
Price
$240
Updated
2021/12/16
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
1g
Price
$65
Updated
2021/12/16
TRC
Product number
B685130
Product name
2-Bromo-3-methylbutyrylurea
Packaging
10g
Price
$105
Updated
2021/12/16
Usbiological
Product number
159423
Product name
2-Bromo-3-methylbutyrylurea
Packaging
1g
Price
$319
Updated
2021/12/16
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Bromisoval Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Bromisovalum,Linhai Duqiao Fine Chemical Factory

Uses

2-Bromo-3-methylbutyrylurea is a hypnotic and sedative drug marketed over the counter in Asian under various brand names.

Definition

ChEBI: An N-acylurea that is urea in which one of the hydrogens is replaced by a 2-bromo-3-methybutanoyl group.

Manufacturing Process

A mixture of 2 kg 2-bromoisovalerylbromide and 1 kg dry urea is heated at 70°C. Then to the reaction mixture is added sodium hydrogen carbonate. 2- Bromo-3-methylbutyrylurea is recrystallized from toluene or water, melting point 149°C.

brand name

Bromural (Knoll).

Therapeutic Function

Sedative, Hypnotic

World Health Organization (WHO)

Bromisoval is a monureide sedative of long standing. It remains available in several countries. However, it releases the bromide ion and prolonged usage can result in chronic bromide accumulation and intoxication.

Safety Profile

Moderately toxic by ingestion. Human systemic effects by ingestion: nausea or vomiting, and coma. A sedative and hypnotic agent. When heated to decomposition it emits very toxic fumes of Brand NOx

Purification Methods

Crystallise it from aqueous EtOH or toluene, and dry it in air. [Beilstein 3 H 63, 3 I 29, 3 II 51, 3 III 123, 3 IV 117.]

Bromisoval Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromisoval Suppliers

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View Lastest Price from Bromisoval manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Bromisoval 496-67-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-20
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bromisoval 496-67-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Bromisoval 496-67-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

496-67-3, BromisovalRelated Search:


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  • A-(BROMOISOVALERYL)UREA
  • ALPHA(BROMOISOVALERYL)UREA
  • LABOTEST-BB LT00134620
  • BROMOVALERYLUREA
  • BROMOISOVALERYLUREA
  • BROMO-ISO-VALERYLUREA (ALPHA)
  • BROMISOVAL
  • (2-bromo-3-methylbutyryl)-ure
  • (alpha-Bromo-.beta,beta.-dimethylpropanoyl)urea
  • (alpha-Bromoisovaleroyl)urea
  • 2-Bromisovalerylmocovina
  • 2-Bromo-3-Methylbutyrylurea
  • 2-Bromo-3-methylbutyrylurea deaux Base GP
  • 2-Bromo-isovaleryl urea
  • 2-Monobromoisovalerylurea
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  • Alluval
  • alpha-Bromisovalerylurea
  • alpha-bromo-beta-dimethylpropanoylurea
  • alpha-Bromoisovaleric acid ureide
  • alpha-bromoisovalericacidureide
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  • Isobromyl
  • monobromoisolvalerylurea
  • Monobromoisovalerylurea
  • N-(2-Bromo-3-methylbutanoyl)urea
  • N-(Ainocar-bonyl)-2-bromo-3-methylbutanamide
  • n-(aminocarbonyl)-2-bromo-3-methyl-butanamid
  • N-(Aminocarbonyl)-2-bromo-3-methylbutanamide
  • Somnurol
  • Urea, (2-bromo-3-methylbutyryl)-
  • Bromisova
  • (RS)-2-Bromoisovalerylurea
  • Urea, (2-bromo-3-methylbutyryl)- (6CI, 8CI)
  • α-Bromoisovaleric acid ureide
  • α-Bromoisovaleroylurea
  • α-Bromo-β-dimethylpropanoylurea
  • alpha-bromoisovaleroylurea
  • Alural
  • B.V.U.
  • Bromaral
  • Bromcarbamide
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  • bromisovalum
  • Bromizoval
  • Bromocarbamide
  • Bromoisovalum
  • Bro-moural
  • Bromoval
  • Bromovalerocarbamide
  • Bromovaleroylurea
  • Bromovaluree
  • Bromoxil
  • Bromural
  • Bromuvan