(-)-CAMPHOR Property

Melting point:

177-179 °C(lit.)

Boiling point:

204 °C(lit.)

alpha 

-44.8° (20/D)(EtOH)

Density 

0.990

vapor density 

5.24 (vs air)

vapor pressure 

4 mm Hg ( 70 °C)

refractive index 

-44 ° (C=20, EtOH)

Flash point:

148 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml

form 

Adhering Crystals or Crystalline Powder

Specific Gravity

0.9853 (18℃)

color 

White to yellow

Odor

at 10.00 % in dipropylene glycol. camphor

Odor Type

camphoreous

explosive limit

0.6-4.5%(V)

optical activity

[α]20/D 43°, c = 10 in ethanol

Water Solubility 

Soluble in water. (0.34 g/L) at 20°C

Merck 

14,1732

BRN 

4291747

Stability:

Stable. Incompatible with strong reducing agents, strong oxidizing agents, chlorinated solvents. Protect from direct sunlight.

InChIKey

DSSYKIVIOFKYAU-OIBJUYFYSA-N

LogP

2.089 (est)

CAS DataBase Reference

464-48-2(CAS DataBase Reference)

EPA Substance Registry System

l-Camphor (464-48-2)

Safety

Hazard Codes 

F,Xi

Risk Statements 

11-36/37/38

Safety Statements 

16-26

RIDADR 

UN 2717 4.1/PG 3

WGK Germany 

1

RTECS 

EX1250000

Autoignition Temperature

870 °F

TSCA 

Yes

HazardClass 

4.1

PackingGroup 

III

HS Code 

29142910

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

(-)-CAMPHOR Chemical Properties,Usage,Production

Uses

(1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one also known by its common name as (-)-Camphor is a chiral intermediate of camphor and is used as a flavour additive in foods and sweetners.

Chemical Properties

white crystals

Uses

(1S)-(-)-Camphor is used as chiral intermediate and chiral auxiliary precursor. It is used in the synthesis of high-potency sweeteners. It acts as catalytic agent and petrochemical additive.

Definition

ChEBI: The S-enantiomer of camphor.

General Description

Colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68°F: 40. Flash point 149°F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure; 14% sublimes within 60 minutes at 176°F and 12 mm Hg.

Air & Water Reactions

Flammable. Slightly water soluble.

Reactivity Profile

(-)-CAMPHOR may be sensitive to heat and direct sunlight. Incompatible with strong oxidizing agents, strong reducing agents and chlorinated solvents. Also incompatible with potassium permanganate. Salts of any kind should not be added to (-)-CAMPHOR in water. Reacts violently with chromic anhydride .

Fire Hazard

(-)-CAMPHOR is flammable.

Purification Methods

Crystallise it from EtOH, 50% EtOH/water, MeOH, or pet ether or from glacial acetic acid by addition of water. It can be sublimed (50o/14mm) and also fractionally crystallised from its own melt. It is steam volatile. It should be stored in tight containers as it is appreciably volatile at room temperature. The solubility is 0.1% (H2O), 100% (EtOH), 173% (Et2O) and 300%