methyl orsellinate
- Product Name
- methyl orsellinate
- CAS No.
- 3187-58-4
- Chemical Name
- methyl orsellinate
- Synonyms
- Methyl;METHYL ORSELLINATE;Methyl o-orsellinate;Orsellinic acid methyl;o-Orsellinic acid methyl;6-Methyl-β-resorcylicacidmethyl;6-Methyl-β-resorcylic acid methyl;BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
- CBNumber
- CB31484897
- Molecular Formula
- C9H10O4
- Formula Weight
- 182.17
- MOL File
- 3187-58-4.mol
methyl orsellinate Property
- Melting point:
- 141-142℃
- Boiling point:
- 339℃
- Density
- 1.296
- Flash point:
- 138℃
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 8.27±0.23(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3
- InChIKey
- NCCWCZLEACWJIN-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=C(C)C=C(O)C=C1O
- LogP
- 2.380 (est)
- EPA Substance Registry System
- Benzoic acid, 2,4-dihydroxy-6-methyl-, methyl ester (3187-58-4)
Safety
- HS Code
- 2918290090
N-Bromosuccinimide Price
- Product number
- M302230
- Product name
- Methyl2,4-Dihydroxy-6-methylbenzoate
- Packaging
- 50mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- M302230
- Product name
- Methyl2,4-Dihydroxy-6-methylbenzoate
- Packaging
- 500mg
- Price
- $205
- Updated
- 2021/12/16
- Product number
- M302230
- Product name
- Methyl2,4-Dihydroxy-6-methylbenzoate
- Packaging
- 2.5g
- Price
- $870
- Updated
- 2021/12/16
- Product number
- CS-0023752
- Product name
- Methylorsellinate
- Packaging
- 250mg
- Price
- $179
- Updated
- 2021/12/16
- Product number
- CS-0023752
- Product name
- Methylorsellinate
- Packaging
- 1g
- Price
- $309
- Updated
- 2021/12/16
methyl orsellinate Chemical Properties,Usage,Production
Uses
Methyl 2,4-Dihydroxy-6-methylbenzoate (methyl orsellinate) is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.
Definition
ChEBI: Orsellinic acid methyl ester is a hydroxybenzoic acid. It has a role as a metabolite.
Biochem/physiol Actions
Methyl orsellinate, an antifungal compound, is produced during submerged culture from Sparassis crispa. Methyl orsellinate have appeared to have higher antifungal activity than sparassol. Methyl orsellinate is a phytotoxic compound; it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. It could inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM; the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity; methyl orsellinate may treat the type 2 diabetes and obesity.
methyl orsellinate Preparation Products And Raw materials
Raw materials
Preparation Products
methyl orsellinate Suppliers
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View Lastest Price from methyl orsellinate manufacturers
- Product
- METHYL ORSELLINATE 3187-58-4
- Price
- US $0.00/KG
- Min. Order
- 0.1KG
- Purity
- 98%
- Supply Ability
- 1000KGS
- Release date
- 2023-10-26
- Product
- Methyl orsellinate 3187-58-4
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-09
- Product
- Methyl 2,4-dihydroxy-6-methylbenzoate 3187-58-4
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-06-06