ChemicalBook > CAS DataBase List > 4-bromoisoindolin-1-one
4-bromoisoindolin-1-one
- Product Name
- 4-bromoisoindolin-1-one
- CAS No.
- 337536-15-9
- Chemical Name
- 4-bromoisoindolin-1-one
- Synonyms
- 4-Bromo-1-isoindolinone;4-bromoisoindolin-1-one;4-BroMoisoindoline-1-one;4-Bromoisoindolin-1-one?New;4-Bromoisoindolin-1-one 97%;4-broMo-2,3-dihydro-1H-isoindol-1-one;1H-Isoindol-1-one,4-broMo-2 3-dihydro-;Ethanone,1-[3,6-dihydroxy-2-methoxy-7-(phenylmethoxy)phenyl]-
- CBNumber
- CB31515791
- Molecular Formula
- C8H6BrNO
- Formula Weight
- 212.04
- MOL File
- 337536-15-9.mol
More
Less
4-bromoisoindolin-1-one Property
- Boiling point:
- 448.9±45.0 °C(Predicted)
- Density
- 1.666
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.69±0.20(Predicted)
- form
- solid
- color
- Off-white to light yellow
- InChI
- InChI=1S/C8H6BrNO/c9-7-3-1-2-5-6(7)4-10-8(5)11/h1-3H,4H2,(H,10,11)
- InChIKey
- TYRICULVJRGSTL-UHFFFAOYSA-N
- SMILES
- C1(=O)C2=C(C(Br)=CC=C2)CN1
More
Less
Safety
- HS Code
- 2933790090
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
More
Less
N-Bromosuccinimide Price
TRC
- Product number
- B997138
- Product name
- 4-Bromo-2,3-dihydroisoindol-1-one
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB32629
- Product name
- 4-Bromoisoindolin-1-one
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB32629
- Product name
- 4-Bromoisoindolin-1-one
- Packaging
- 1g
- Price
- $94
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 074520
- Product name
- 4-Bromoisoindolin-1-one
- Purity
- 95+%
- Packaging
- 1g
- Price
- $102
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FB32629
- Product name
- 4-Bromoisoindolin-1-one
- Packaging
- 5G
- Price
- $280
- Updated
- 2021/12/16
More
Less
4-bromoisoindolin-1-one Chemical Properties,Usage,Production
Uses
4-bromoisoindolin-1-one can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
To a solution of the 3-bromo-2-bromomethyl-benzoic acid methyl ester (2.74 g, 8.88 [MMOL)] in tetrahydrofuran (70 [ML)] at [0??C] was added 30 percent aq. ammonia (10 ml) and the mixture stirred at room temperature under nitrogen for 18 hours. The solvent was removed by evaporation under reduced pressure. The white residue was partitioned between ethyl acetate (50 mi) and 2M citric acid (50 [ML).] The ethyl acetate was dried magnesium sulfate, filtered and solvent removed by evaporation under reduced pressure. The orange oil was dissolved in minimum [DICHLOROMETHANE] and purified by flash chromatography on silica gel eluting with a solvent gradient of [DICHOROMETHANE/METHANOL] (9: 1) to give the title compound (1.5 g, 80 percent) as a white solid.
References
[1] Patent: WO2007/5668, 2007, A2. Location in patent: Page/Page column 36-37
[2] Bioorganic and Medicinal Chemistry, 2008, vol. 16, # 6, p. 3091 - 3107
[3] Patent: US2008/171754, 2008, A1. Location in patent: Page/Page column 104
[4] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 17, p. 4505 - 4509
[5] Patent: WO2004/14357, 2004, A2. Location in patent: Page/Page column 39-40
4-bromoisoindolin-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
4-bromoisoindolin-1-one Suppliers
- Tel
- 13642727863
- 1009049100@qq.com
- Country
- China
- ProdList
- 656
- Advantage
- 58
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9309
- Advantage
- 66
- Tel
- 21-57721279
- Fax
- QQ：14057904
- sales@shydchem.com.cn
- Country
- China
- ProdList
- 998
- Advantage
- 56
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- 021-34975603-808 18721111801
- Fax
- +86-21-34975602-805
- sales@bocpharma.com
- Country
- China
- ProdList
- 1009
- Advantage
- 64
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 16077
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 0532-0532-88191853 13061484198
- Fax
- +86-532-88191853
- sales@carelongchem.com
- Country
- China
- ProdList
- 439
- Advantage
- 57
- Tel
- 027-88041443 13072715837
- Fax
- 027-51829379
- sales@hetero-chem.com
- Country
- China
- ProdList
- 696
- Advantage
- 58
- Tel
- 025-58395930
- Fax
- 025-5861-9182
- sales@acornpharma.com
- Country
- China
- ProdList
- 982
- Advantage
- 60
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 025-58196018 800028039
- Fax
- 025-83453306
- sales@fartop.net
- Country
- China
- ProdList
- 2229
- Advantage
- 55
- Tel
- +86 21 61551611
- Fax
- +86 21 50676805
- Country
- China
- ProdList
- 9891
- Advantage
- 58
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 0371-86615086 18203638366 0371-86159066 13526786601
- Fax
- 0371-86159066
- Country
- China
- ProdList
- 2015
- Advantage
- 60
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 15928766785 15928766785
- Fax
- QQ961458712
- wupengcheng@astatech.cn
- Country
- China
- ProdList
- 1987
- Advantage
- 55
- Tel
- 021-54880687
- Fax
- 021-54880687
- Country
- China
- ProdList
- 511
- Advantage
- 55
- Tel
- 021-61995394 18916691159
- chemicalsea@163.com
- Country
- China
- ProdList
- 1972
- Advantage
- 58
- Tel
- 18621020637 18621020637;
- sales@sunsynpharma.com
- Country
- China
- ProdList
- 288
- Advantage
- 55
- Tel
- 13052276172
- Fax
- 13052276172
- product@yuyuanpharm.com
- Country
- China
- ProdList
- 493
- Advantage
- 55
- Tel
- 13120367189
- Fax
- 021-50315529
- mychess007@163.com
- Country
- China
- ProdList
- 1994
- Advantage
- 55
- Tel
- 025-025-52700520 18914499889
- Fax
- 025-52700520
- sales@yfbiotech.com
- Country
- China
- ProdList
- 495
- Advantage
- 58
- Tel
- sales@ahpharmatech.com
- Country
- China
- ProdList
- 5734
- Advantage
- 55
- Tel
- 0571-87396432
- Fax
- 0571-87396431
- sales@jhechem.com
- Country
- China
- ProdList
- 14912
- Advantage
- 59
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 13391076197
- tombiopharma@163.com
- Country
- China
- ProdList
- 4987
- Advantage
- 55
- Tel
- 010-56330744 18310155299
- Fax
- 010-56330744
- sales@labter.com.cn
- Country
- China
- ProdList
- 20000
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 18189674620
- 761137152@qq.com
- Country
- China
- ProdList
- 489
- Advantage
- 55
- Tel
- 531-88883606 15688880361
- Fax
- +86-531-69950228 QQ839101288 QQ2793626495
- sales@jnrxchem.com
- Country
- China
- ProdList
- 111
- Advantage
- 55
- Tel
- +86-15251749953
- Fax
- -
- pl_pharmatech@163.com
- Country
- China
- ProdList
- 82
- Advantage
- 55
- Tel
- 0371-67759225 13526468238
- Fax
- +86-37155919558
- sales@hqmat.com
- Country
- China
- ProdList
- 812
- Advantage
- 55
- Tel
- 010-60400365-8001 15910885229
- Fax
- 010-60400361
- service@bellenchem.com
- Country
- China
- ProdList
- 4514
- Advantage
- 60
- Tel
- 0512-63009836 18994340901
- Fax
- 0512-63006936
- helen@struchem.com
- Country
- China
- ProdList
- 3981
- Advantage
- 60
- Tel
- 18-086626237 18086626237
- Fax
- qq:2693528373
- 2693528373@qq.com
- Country
- China
- ProdList
- 2973
- Advantage
- 56
- Tel
- 28-87999436 02887999436
- Fax
- QQ:2746983436
- sales@sano-chem.com
- Country
- China
- ProdList
- 3795
- Advantage
- 55
- Tel
- 86-(0)21-31261262 373522135
- Fax
- 86-(0)21-33250524
- sales@novochemy.com
- Country
- China
- ProdList
- 6498
- Advantage
- 58
- Tel
- 13817485796
- Fax
- QQ:895624079
- tim@wisacheampharm.com
- Country
- China
- ProdList
- 3593
- Advantage
- 58
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 021-34979681; 17701870669
- Fax
- 021-34979681
- 41513101@qq.com
- Country
- China
- ProdList
- 1785
- Advantage
- 55
- Tel
- 021-58088081 Q2635253576
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 1984
- Advantage
- 55
- Tel
- 18114022054; 18114022054
- Fax
- +86-25-58857385
- 3317707757@qq.com
- Country
- China
- ProdList
- 301
- Advantage
- 55
- Tel
- 025-57043319 15261831516
- Fax
- 025-57043319
- 307514552@qq.com
- Country
- China
- ProdList
- 251
- Advantage
- 50
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9923
- Advantage
- 55
More
Less
View Lastest Price from 4-bromoisoindolin-1-one manufacturers
Career Henan Chemical Co
- Product
- 4-bromoisoindolin-1-one 337536-15-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500KG
- Release date
- 2018-08-19
337536-15-9, 4-bromoisoindolin-1-oneRelated Search:
methyl 4-bromoquinoline-8-carboxylate
6-bromoisoindolin-1-one
6-NITRO-ISOINDOLIN-1-ONE
5-BROMO-2,3-DIHYDRO-ISOINDOL-1-ONE
4-nitroisoindolin-1-one
6-AMino-2,3-dihydroisoindol-1-one
1,2-Bis(tetrabromophthalimido) ethane
3,4,5,6-TETRABROMOPHTHALIMIDE
4-BROMO-6,7-DIMETHOXY-ISOINDOLIN-1-ONE
4-bromoisoindolin-1-one
AURORA 17475
AURORA 17478
4,5,6,7-TETRABROMO-2-(OXIRAN-2-YLMETHYL)ISOINDOLINE-1,3-DIONE
N,N'-(methylenedi-p-phenylene)bis[3,4,5,6,-tetrabromophthalimide]
AURORA 17477
AURORA 17474
AURORA 17308
AURORA 17476