(S)-(-)-2-Chloropropionic acid

Product Name: (S)-(-)-2-Chloropropionic acid
CAS No.: 29617-66-1
Chemical Name: (S)-(-)-2-Chloropropionic acid
Synonyms: 2-CHLOROPROPANOIC ACID;L-α-Chloropropionic acid;L-CPA;)-2-Chlo;(S)-()-2-Chlo;(s)-propanoicaci;L-2-CHLOROPROPINONICAL;S-(-)-2-Chloropropanoic;S-2-Chlorpropionic acid;l-2-chloropropanoicacid
CBNumber: CB3161267
Molecular Formula: C3H5ClO2
Formula Weight: 108.52
MOL File: 29617-66-1.mol

More

Less

(S)-(-)-2-Chloropropionic acid Property

Melting point:: 4 °C
Boiling point:: 77 °C/10 mmHg (lit.)
alpha: -14.5 º (c=neat)
Density: 1.249 g/mL at 25 °C (lit.)
vapor pressure: 5hPa at 20℃
refractive index: n20/D 1.436
Flash point:: 140 °F
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
pka: 2.83(at 25℃)
form: Liquid
color: Clear light yellow
optical activity: [α]25/D -14°, neat
Water Solubility: soluble
BRN: 1720257
LogP: 0.82 at 20.5℃
CAS DataBase Reference: 29617-66-1(CAS DataBase Reference)
NIST Chemistry Reference: (S)-(-)-2-chloropropionic acid(29617-66-1)

More

Less

Safety

Hazard Codes: C
Risk Statements: 21/22-35-48/22
Safety Statements: 23-26-28-36/37/39-45
RIDADR: UN 2511 8/PG 3
WGK Germany: 1
RTECS: UA2451950
HazardClass: 8
PackingGroup: III
HS Code: 29159080

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H312Harmful in contact with skin

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P390Absorb spillage to prevent material damage.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: C1373
Product name: (S)-(-)-2-Chloropropionic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $16
Updated: 2024/03/01

TCI Chemical

Product number: C1373
Product name: (S)-(-)-2-Chloropropionic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $29
Updated: 2024/03/01

Alfa Aesar

Product number: L09427
Product name: (S)-(-)-2-Chloropropionic acid, 99%
Packaging: 5g
Price: $59.65
Updated: 2024/03/01

Alfa Aesar

Product number: L09427
Product name: (S)-(-)-2-Chloropropionic acid, 99%
Packaging: 25g
Price: $164.65
Updated: 2024/03/01

TCI Chemical

Product number: C1373
Product name: (S)-(-)-2-Chloropropionic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $81
Updated: 2024/03/01

More

Less

(S)-(-)-2-Chloropropionic acid Chemical Properties,Usage,Production

Description

(S)-2-chloropropanoic acid is a monocarboxylic acid that is propanoic acid substituted at position 2 by a chloro group (the S-enantiomer). It has a role as a neurotoxin. It is a monocarboxylic acid and a chlorocarboxylic acid. It is functionally related to propionic acid. It is a conjugate acid of a (S)-2-chloropropanoate.

Chemical Properties

Colourless Oil

Uses

Through the stereo displacement of (S)-(-)-2-Chloropropionic acid PPAR Agonist can be synthesized via asymmetric hydrogenation of a cinnamic acid derivative.

Definition

ChEBI: A monocarboxylic acid that is propanoic acid substitued at position 2 by a chloro group (the S-enantiomer).

General Description

2-Chloropropionic acid is an essential raw material for synthesising pesticides, dyes and medicines. Its application involves many sectors of the national economy and people's daily lives. It is an essential fine chemical product. In particular, (S)-(-)-2-Chloropropionic acid is a crucial intermediate for synthesising highly efficient and low-toxic aromatic oxygen propionic acid herbicides. For example, it can be used to synthesize (R)-2-(4-hydroxyphenoxy) propionic acid (ester) intermediates, fenthionyl, fenthionyl, fenthionyl, etc. At present, the preparation methods of (S)-(-)-2-chloropropionic acid and (R)-(+)-2-chloropropionic acid include: (1) chemical resolution method; (2) bioenzymatic resolution method; (3) chromatographic resolution method; (4) asymmetric synthesis method, etc.

Flammability and Explosibility

Non flammable

Synthesis

JP 061172846 provides a method for resolving racemic 2-chloropropionic acid using an optically active 2-aryl-2-isopropylethylamine as a resolving agent to obtain (S)-(-)-2-Chloropropionic acid (yield 24.2% and enantiomeric excess 83.2%). DE 4328231 provides a method for catalyzing the hydrolysis of 2-chloropropionic acid esters by a hydrolase (Pseudomonas Lipase) to hydrolyze (S)-2-chloropropionic acid esters to generate (S)-(-)-2-Chloropropionic acid.

Purification Methods

Purify the acid by fractionating twice through a 115cm Podbielniak column (p 11, calculated 50 theoretical plates at atmospheric pressure) using a take-off ratio of 1:5. The acid chloride is prepared by dissolving the acid in SOCl2, adding a few drops of PCl3, refluxing and then distilling through a 30cm column, b 53o/100mm, [] -4.6o (neat), d 1.2689, n1.4368. [Fu et al. J Am Chem Soc 76 6954 1954, Beilstein 2 IV 745.]

(S)-(-)-2-Chloropropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(S)-(-)-2-Chloropropionic acid Suppliers

Americas 1 Belgium 2 Canada 2 China 278 Europe 3 France 1 Germany 4 India 6 Japan 2 Slovakia 1 South Korea 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 13 United States 36 Global 353

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Alfa Chemistry

Tel
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 24072
Advantage: 58

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

Aceschem Inc.

Tel: +1-817863-6948 +1-（817）863-6948
Email: sales@aceschem.com
Country: United States
ProdList: 19632
Advantage: 58

Combi-Blocks Inc.

Tel: --
Fax: --
Email: sales@combi-blocks.com
Country: United States
ProdList: 6618
Advantage: 69

SynQuest Laboratories, Inc.

Tel: --
Fax: --
Email: info@synquestlabs.com
Country: United States
ProdList: 6871
Advantage: 62

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Frontier Scientific, Inc.

Tel: --
Fax: --
Email: sales@frontiersci.com
Country: United States
ProdList: 6222
Advantage: 86

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

CarboMer, Inc.

Tel: --
Fax: --
Email: sales@carbomer.com
Country: United States
ProdList: 4026
Advantage: 67

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6962
Advantage: 56

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Magical Scientific LLC

Tel: --
Fax: --
Country: United States
ProdList: 703
Advantage: 0

Medical Isotopes

Tel: --
Fax: --
Email: stohler@medicalisotopes.com
Country: United States
ProdList: 6181
Advantage: 68

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

Chiral Management

Tel: --
Fax: --
Email: sales@chiralmanagement.com
Country: United States
ProdList: 1332
Advantage: 30

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

APAC Pharmaceutical, LLC

Tel: --
Fax: --
Email: sales@apacpharma.com
Country: United States
ProdList: 6322
Advantage: 38

Ivy Fine Chemicals

Tel: --
Fax: --
Email: sales@ivychem.com
Country: United States
ProdList: 6493
Advantage: 58

Magical Scientific LLP

Tel: --
Fax: --
Country: United States
ProdList: 750
Advantage: 43

Beta Pharma, Inc.

Tel: --
Fax: --
Email: sales@betapharma.com
Country: United States
ProdList: 6226
Advantage: 60

Acros Organics USA

Tel: --
Fax: --
Email: eveleth@fisherchem.com
Country: United States
ProdList: 3846
Advantage: 81

BASF Corporation

Tel: --
Fax: --
Country: United States
ProdList: 573
Advantage: 86

Pfaltz & Bauer, Inc.

Tel: --
Fax: --
Email: sales@pfaltzandbauer.com
Country: United States
ProdList: 6828
Advantage: 72

Norse Laboratories, Inc.

Tel: --
Fax: --
Email: sylvia@norselabs.com
Country: United States
ProdList: 105
Advantage: 30

Ennova MedChem Group Inc., formerly Arch Corporation

Tel: --
Fax: --
Email: sales@ennovamedchem.com
Country: United States
ProdList: 1218
Advantage: 42

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

BOSCHE SCIENTIFIC, LLC

Tel: --
Fax: --
Email: Sales@BoscheSci.com
Country: United States
ProdList: 6477
Advantage: 55

More

Less

View Lastest Price from (S)-(-)-2-Chloropropionic acid manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: (S)-(-)-2-Chloropropionic acid 29617-66-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-19

Hebei Chuanghai Biotechnology Co,.LTD

Product: (S)-(-)-2-Chloropropionic acid 29617-66-1
Price: US $50.60/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 5000kg
Release date: 2024-08-20

Hebei Kingfiner Technology Development Co.Ltd

Product: (S)-(-)-2-Chloropropionic acid 29617-66-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000kg
Release date: 2024-06-24

29617-66-1, (S)-(-)-2-Chloropropionic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate b-Chloropropionic acid,3-CHLOROPROPIONIC ACID:SS-CHLOROPROPIONIC ACID 2-CHLOROPROPIONIC ACID pract,2-CHLOROPROPIONIC ACID (92%),(n)-2-chloropropionic acid,(+/-)-2-CHLOROPROPIONIC ACID,2-CHLOROPROPIONIC ACID,A-CHLOROPROPIONIC ACID Clobetasol propionate Folic acid Glycine Beclomethasone dipropionate Diethyl chloromalonate (S)-2-CHLORO-3-METHYLBUTYRIC ACID (S)-2-Chloropropionic acid methyl (S)-2-CHLORO-4-METHYL-N-VALERIC ACID (S)-2-CHLORO-N-BUTYRIC ACID Dimethyl chloromalonate (2S,3S)-2-CHLORO-3-METHYL-N-VALERIC ACID (S)-2-CHLOROSUCCINIC ACID DIISOPROPYL CHLOROMALONATE 2,2-DICHLOROPROPIONIC ACID SODIUM SALT (S)-2-CHLOROPROPIONIC ACID LSOBUTYL ESTER,(S)-2-Chloropropionic acid 2-methylpropyl ester

PROPANOIC ACID, 2-CHLORO-, (2S)-

(S)-(-)-2-CHLOROPROPIONIC ACID

(S)-2-CHLOROPROPIONIC ACID

(S)-(-)-2-CHLOROPROPIONOIC ACID

(S)-(-)-2-CHLOROPROPANOIC ACID

(2s)-chloropropanoicacid

L-α-Chloropropionic acid

L-(-)-2-Chloro Proxic Acid

L-2-CHLOROPROPINONICAL

S-(-)-2-Chloropropanoic

(S)-(-)-2-CHLOROPROPIONIC ACID 98% OPTICAL95%

(S)-(-)-2-Chloropropionic acid, ChiPros(tm 98%, ee 96+%

(S)-(-)-2-Chloropropanoic acid, L-α-Chloropropionic acid

(S)-()-2-Chloropropionic acid,(S)-()-2-Chloropropanoic acid, L-α-Chloropropionic acid

)-2-Chlo

(2S)-2-Chloropropanoic acid

(2S)-2-Chloropropionic acid

(S)-2-Chloropropionic Acid,99%e.e.

(S)-()-2-Chlo

(S)-a-chloropropionic acid

(S)-(-)-2-Chloropropionic acid, 98% 500MG

(S)-(-)-2-Chloropropionic acid,98%

(S)-(-)-2-Chloropropionic acid 99%

S-2-Chlorpropionic acid

S(-) 2-Chloropropionic acid (LCPA)

(s)-propanoicaci

2(s)-chloropropionicacid

2-chloro-,(2S)-Propanoicacid

alpha-l-chloropropionicacid

l-2-chloropropanoicacid

l-2-chloropropionicacid

L-ALPHA-CHLOROPROPIONIC ACID

L-(A)-CHLOROPROPIONIC ACID

2-CHLOROPROPANOIC ACID

(S)-(-)-2-Chloropropionic Acid &gt

(S)-α-chloropropionic acid

(S)-2-Chloropropanoicaci

L-CPA

(-)-2-Chloropropanoic acid

S-2-Chloropropionic Acid pure, 98%

2-Octyl-1-dodecanol 5333-42-6

29617-66-1

598-79-7

C3H5ClO2

Asymmetric Synthesis

Carboxylic Acids

Chiral Building Blocks

Chiral Compounds (Building Blocks for Liquid Crystals)

Building Blocks for Liquid Crystals

Carboxylic Acids (Chiral)

Organic Building Blocks

Heterocycle-Pyridine series

Miscellaneous Reagents

Building Blocks for Liquid Crystals

Carboxylic Acids (Chiral)

Chiral Building Blocks

Chiral Compounds (Building Blocks for Liquid Crystals)

Functional Materials