ChemicalBook > CAS DataBase List > Methyltrienolone

Methyltrienolone

Product Name
Methyltrienolone
CAS No.
965-93-5
Chemical Name
Methyltrienolone
Synonyms
METRIBOLONE;R1881;Methytrienolone;METHYLTRIENOLONE(R-1881);RU-1881;trienoL;NSC 92858;Methyltrienone;11-triene-3-one;METHYLTRIENOLONE
CBNumber
CB3221633
Molecular Formula
C19H24O2
Formula Weight
284.39
MOL File
965-93-5.mol
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Methyltrienolone Property

Melting point:
170°
alpha 
D20 -58.7° (c = 0.5 in ethanol)
Boiling point:
485.9±45.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: ≥10mg/mL
form 
powder
pka
14.79±0.40(Predicted)
color 
light yellow to yellow
optical activity
[α]/D -48 to -68°
InChI
InChI=1/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/s3
InChIKey
CCCIJQPRIXGQOE-XWSJACJDSA-N
SMILES
[C@@]12([H])CC[C@@](O)(C)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H] |&1:0,4,7,21,r|
CAS DataBase Reference
965-93-5(CAS DataBase Reference)
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Safety

WGK Germany 
3
DEA Controlled Substances
CSCN: 4000
CSA SCH: Schedule III
NARC: No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R0908
Product name
R1881
Purity
≥98% (HPLC)
Packaging
10mg
Price
$240
Updated
2024/03/01
Sigma-Aldrich
Product number
R0908
Product name
R1881
Purity
≥98% (HPLC)
Packaging
50mg
Price
$922
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0003347
Product name
METHYLTRIENOLONE
Purity
95.00%
Packaging
1MG
Price
$837.38
Updated
2021/12/16
AHH
Product number
MT-54276
Product name
Methyltrienolone
Purity
98%
Packaging
25g
Price
$830
Updated
2021/12/16
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Methyltrienolone Chemical Properties,Usage,Production

Description

Methyltrienolone, also called metribolone, is an orally active anabolic-androgen steroid being a 17α-alkylated nandrolone (19-nortestosterone) derivative. It is not sold as a prescription drug or a dietary supplement due to its strong androgenic side effects and liver toxicity. However, it is often used as the reference point for in vitro biological activity for biochemical studies. It can bind strongly to the androgen receptor and can be used as an affinity label of the androgen receptor in the prostate and prostatic tumors.

Chemical Properties

Pale Yellow Solid

Uses

Methyltrienolone is a synthetic derivative of testosterone that is used in the medical field as an androgen and anabolic agent. It has been used to treat breast cancer, prostate cancer, and other cancers that are sensitive to hormones.

Definition

ChEBI: Methyltrienolone, also known as 7beta-hydroxy-17-methylestra-4,9,11-trien-3-one, is a synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors. It has a role as an androgen. It is an anabolic androgenic steroid, a 17beta-hydroxy steroid and a 3-oxo steroid. It derives from a hydride of an estrane.

Biochem/physiol Actions

Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. R1881, also known as methyltrienolone, is a synthetic androgen. It is the gold standard AR agonist.

References

https://en.wikipedia.org/wiki/Metribolone
https://www.drugbank.ca/drugs/DB02998
https://pubchem.ncbi.nlm.nih.gov/compound/Methyltrienolone
Kazlauskas R. (2010) Designer Steroids. In: Thieme D., Hemmersbach P. (eds) Doping in Sports: Biochemical Principles, Effects and Analysis. Handbook of Experimental Pharmacology, vol 195. Springer, Berlin, Heidelberg

Methyltrienolone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyltrienolone manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
metribolone 965-93-5
Price
US $60.00-40.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
20
Release date
2024-03-15
Wuhan Cell Pharmaceutical Co., Ltd
Product
Metribolone;Methyl trenbolone;Methyltrienolone 965-93-5
Price
US $9.90-100.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
500kg
Release date
2023-04-04
Shanghai Getian Industrial Co., LTD
Product
Methyltrienolone 965-93-5
Price
US $20.00/box
Min. Order
1box
Purity
99%
Supply Ability
10000box
Release date
2024-04-30

965-93-5, MethyltrienoloneRelated Search:


  • METRIBOLONE
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  • 17b-hydroxy-17-methylestra-4,9,11-trien-3-one
  • 17A-METHYL-TRENBOLONE
  • R1881
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  • 17β-Hydroxy-17-methylestra-4,9,11-trien-3-one
  • RU-1881
  • (17b)-17-Hydroxy-17-methyl-estra-4,9,11-trien-3-one
  • NSC 92858
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  • Metribolone (Methyltrienolone) R1881
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