ChemicalBook > CAS DataBase List > 2-(Hydroxymethyl)pyridine

2-(Hydroxymethyl)pyridine

Product Name
2-(Hydroxymethyl)pyridine
CAS No.
586-98-1
Chemical Name
2-(Hydroxymethyl)pyridine
Synonyms
2-PYRIDINEMETHANOL;Piconol;(S)-Tryptophan Methyl ester hydrochloride;2-Pyridine;PyridineMethanol;2-PYRIDYLMETHANOL;PYRIDINE-2-METHANOL;PYRIDIN-2-YL-METHANOL;2-Pyridine methanol(2-hydromethyl pyridine);2-HMP
CBNumber
CB3222786
Molecular Formula
C6H7NO
Formula Weight
109.13
MOL File
586-98-1.mol
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2-(Hydroxymethyl)pyridine Property

Melting point:
5 °C
Boiling point:
112-113 °C/16 mmHg (lit.)
Density 
1.131 g/mL at 25 °C (lit.)
vapor pressure 
3.47Pa at 25℃
refractive index 
n20/D 1.543(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
miscible
form 
Liquid
pka
13.48±0.10(Predicted)
color 
Clear colorless to yellow or brown
Specific Gravity
1.131
PH
6-8 (100g/l, H2O, 20℃)
Odor
pyridine odor
Water Solubility 
miscible
Sensitive 
Hygroscopic
BRN 
107849
InChIKey
SHNUBALDGXWUJI-UHFFFAOYSA-N
LogP
0.11
CAS DataBase Reference
586-98-1(CAS DataBase Reference)
NIST Chemistry Reference
Piconol(586-98-1)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
UT4689000
3-8
Hazard Note 
Irritant/Keep Cold/Hygroscopic
HazardClass 
IRRITANT, HYGROSCOPIC, KEEP COLD
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P66602
Product name
2-Pyridinemethanol
Purity
98%
Packaging
25g
Price
$45.7
Updated
2025/07/31
Sigma-Aldrich
Product number
P66602
Product name
2-Pyridinemethanol
Purity
98%
Packaging
100g
Price
$71.1
Updated
2025/07/31
TCI Chemical
Product number
P0556
Product name
2-Pyridinemethanol
Purity
>98.0%(GC)
Packaging
25g
Price
$46
Updated
2025/07/31
TCI Chemical
Product number
P0556
Product name
2-Pyridinemethanol
Purity
>98.0%(GC)
Packaging
100g
Price
$74
Updated
2021/12/16
TRC
Product number
H947995
Product name
2-(Hydroxymethyl)pyridine
Packaging
50g
Price
$1100
Updated
2021/12/16
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2-(Hydroxymethyl)pyridine Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLORLESS TO YELLOW OR BROWN LIQUID

Uses

decongestant

Uses

A pyridylalcohol with hypoglycemic activity and potential apoptotic effect in human leukemia cells.

Uses

2-Pyridinemethanol is used as a pyridylalcohol with hypoglycemic activity.

Preparation

The preparation of 2-(Hydroxymethyl)pyridine is as follows:NaOH (0.5 g, 12.5 mmol), Al2O3 (2.0 g, 19.6 mmol), aldehyde 1f-g (2 mmol) and H2O (400 μL) were grinded in a mortar. Next, the paste were placed in a glass 10 mL pressure vials and reaction was carried out in microwave reactor: standard mode (200 W), 100 °C, 2 min. After that, reaction mixture was extracted with DCM (2 × 20 mL). Organic layer was evaporated under reduce pressure yielding 2f-g. Solid residue was washed by water (2 × 15 mL). Aqueous phase was acidify with 1N HCl to pH 5.5 and centrifuged. After that aqueous layer was pour down and precipitate was lyophilisated. Products 3f-g were obtained as white solids.

Definition

ChEBI: 2-Pyridinylmethanol is a member of pyridines.

2-(Hydroxymethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-(Hydroxymethyl)pyridine manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
2-(Hydroxymethyl)pyridine 586-98-1
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-09
Henan Aochuang Chemical Co.,Ltd.
Product
2-(Hydroxymethyl)pyridine 586-98-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-29
Hebei Longbang Technology Co., Ltd
Product
2-(Hydroxymethyl)pyridine 586-98-1
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-11

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