ChemicalBook > CAS DataBase List > 4-Hydroxybenzyl alcohol

4-Hydroxybenzyl alcohol

Product Name
4-Hydroxybenzyl alcohol
CAS No.
623-05-2
Chemical Name
4-Hydroxybenzyl alcohol
Synonyms
4-(Hydroxymethyl)phenol;P-HYDROXYBENZYL ALCOHOL;Gastrodigenin;p-Hydroxybenzyl;p-Methylolphenol;4-hydroxyphenyl Methanol;P-hydroxylbenzyl alcohol;Benzenemethanol, 4-hydroxy-;FEMA 3987;ω-Hydroxycresol
CBNumber
CB3224331
Molecular Formula
C7H8O2
Formula Weight
124.14
MOL File
623-05-2.mol
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4-Hydroxybenzyl alcohol Property

Melting point:
114-122 °C(lit.)
Boiling point:
251-253°C
Density 
1.1006 (rough estimate)
refractive index 
1.5035 (estimate)
FEMA 
3987 | 4-HYDROXYBENZYL ALCOHOL
Flash point:
251-253°C
storage temp. 
Store below +30°C.
solubility 
6.7g/l soluble
form 
Crystalline Powder
pka
pK1:9.82 (25°C)
color 
Pink to beige
Odor
at 100.00 %. fruity bitter almond sweet coconut
Odor Type
fruity
Water Solubility 
Soluble in water (6.7 mg/ml at 20°C), dioxane (100 mg/ml), 1N NaOH (50 mg/ml), DMSO, and methanol.
Sensitive 
Light Sensitive/Air Sensitive
JECFA Number
955
BRN 
1858967
InChIKey
BVJSUAQZOZWCKN-UHFFFAOYSA-N
LogP
0.21
CAS DataBase Reference
623-05-2(CAS DataBase Reference)
NIST Chemistry Reference
Benzenemethanol, 4-hydroxy-(623-05-2)
EPA Substance Registry System
4-Hydroxybenzenemethanol (623-05-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36-36/37/38
Safety Statements 
26-24/25-36
WGK Germany 
3
RTECS 
DA4796800
8-9-23
Hazard Note 
Irritant/Keep Cold/Air Sensitive/Light Sensitive
HS Code 
29072900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H20806
Product name
4-Hydroxybenzyl alcohol
Purity
99%
Packaging
10g
Price
$58.9
Updated
2024/03/01
TCI Chemical
Product number
H0224
Product name
4-Hydroxybenzyl Alcohol
Purity
>97.0%(GC)
Packaging
25g
Price
$30
Updated
2024/03/01
TCI Chemical
Product number
H0224
Product name
4-Hydroxybenzyl Alcohol
Purity
>97.0%(GC)
Packaging
100g
Price
$115
Updated
2024/03/01
Alfa Aesar
Product number
A13132
Product name
4-Hydroxybenzyl alcohol, 99%
Packaging
50g
Price
$82.3
Updated
2024/03/01
Alfa Aesar
Product number
A13132
Product name
4-Hydroxybenzyl alcohol, 99%
Packaging
100g
Price
$145.65
Updated
2024/03/01
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4-Hydroxybenzyl alcohol Chemical Properties,Usage,Production

Chemical Properties

Pink to beige crystalline powder

Chemical Properties

4-Hydroxybenzyl alcohol is a white crystalline powder with slightly fruity-sweet coconut odor

Occurrence

Reportedly found in vanilla, Bourbon (Vanilla plantifolia Andrew

Uses

4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Preparation

Prepared from p-cresol by using the microorganism, Pseudomonas putida.

Definition

ChEBI: P-hydroxybenzyl alcohol is a member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung. It has a role as a plant metabolite. It is a member of phenols and a member of benzyl alcohols.

General Description

4-Hydroxybenzyl alcohol (HBA) is a phenolic compound found in Gastrodia elata. It is as an antioxidant and anti-asthmatic agent.

Flammability and Explosibility

Not classified

Contact allergens

Methylol phenols are sensitizers contained in resins based on phenol and formaldehyde of the resol type. Cross-reactivity is possible with other phenol derivative molecules.

IC 50

IC50 >0.2 mM (human); ALDH5A1: IC50 >1 mM (human); ABAT: IC50 >1 mM (human); Tyrosinase: IC50 >1 mM (Agaricus bisporus)

Purification Methods

Crystallise the alcohol from H2O, *C6H6 (m 124o), *C6H6/EtOH or ClCH2CH2Cl (m 122o). [Beilstein 6 III 4546, 6 IV 5909.]

4-Hydroxybenzyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxybenzyl alcohol Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
ecochem international chemical broker
Tel
--
Fax
--
Email
export@ecochem.dk
Country
Europe
ProdList
6371
Advantage
66
kemikalieimport
Tel
--
Fax
--
Email
Sales@kemikalieimport.dk
Country
Europe
ProdList
6685
Advantage
47
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View Lastest Price from 4-Hydroxybenzyl alcohol manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
4-Hydroxybenzyl Alcohol 623-05-2
Price
US $100.00-45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-06
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Hydroxybenzyl alcohol 623-05-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
5KG
Purity
99%min
Supply Ability
15tons/month
Release date
2021-06-07
Hebei Weibang Biotechnology Co., Ltd
Product
4-Hydroxybenzyl alcohol 623-05-2
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-22

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