ChemicalBook > CAS DataBase List > 3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol
3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol
- Product Name
- 3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol
- CAS No.
- 70677-47-3
- Chemical Name
- 3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol
- Synonyms
- Canniprene;3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol;Phenol, 3-[2-(3-hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-buten-1-yl)-
- CBNumber
- CB32397271
- Molecular Formula
- C21H26O4
- Formula Weight
- 342.43
- MOL File
- 70677-47-3.mol
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3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Property
- Boiling point:
- 500.3±45.0 °C(Predicted)
- Density
- 1.128±0.06 g/cm3(Predicted)
- pka
- 9.63±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Arctom
- Product number
- CFN97198
- Product name
- Canniprene
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $553
- Updated
- 2021/12/16
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3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Chemical Properties,Usage,Production
Uses
Canniprene, an isoprenylated bibenzyl unique to Cannabis sativa, is a potent inhibitor of 5-lipoxygenase (5-LO) activity (IC50=0.4 μM) and cyclooxygenase/microsomal prostaglandin E2 synthase (PGE2; IC50=10 μM). Canniprene inhibits the production of inflammatory eicosanoids and affects the generation of prostaglandins[1].
IC 50
5-LO: 0.4 μM (IC50); PGE2: 10 μM (IC50)
References
[1] Allegrone G, et al. The Bibenzyl Canniprene Inhibits the Production of Pro-Inflammatory Eicosanoids and Selectively Accumulates in Some Cannabis sativa Strains. J Nat Prod. 2017 Mar 24;80(3):731-734. DOI:10.1021/acs.jnatprod.6b01126
3-[2-(3-Hydroxy-5-methoxyphenyl)ethyl]-6-methoxy-2-(3-methyl-2-butenyl)phenol Preparation Products And Raw materials
Raw materials
Preparation Products
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