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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT

Product Name
BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
CAS No.
87779-49-5
Chemical Name
BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
Synonyms
Bz-VGR-AMC;Bz-Val-Gly-Arg-AMC;BZ-VAL-GLY-ARG-AMC TFA SALT;Bz-Val-Gly-Arg-AMC (I-1085.0050);BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT;N-Benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide;L-Argininamide, N-benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;N-[(2S)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]benzamide
CBNumber
CB3241806
Molecular Formula
C30H37N7O6
Formula Weight
591.66
MOL File
87779-49-5.mol
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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Property

storage temp. 
-15°C
solubility 
Soluble in DMSO.
form 
White powder.
color 
White
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FB110482
Product name
Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging
1mg
Price
$80
Updated
2021/12/16
Chem-Impex
Product number
32842
Product name
Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging
5MG
Price
$100
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB110482
Product name
Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging
2mg
Price
$125
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB110482
Product name
Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging
5mg
Price
$200
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB110482
Product name
Bz-Val-Gly-Arg-AMC trifluoroacetate salt
Packaging
10mg
Price
$320
Updated
2021/12/16
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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Chemical Properties,Usage,Production

Description

Bz-VGR-AMC (87779-49-5) may be used for measuring the trypsin-like activity of the 20S proteasome, in combination with Suc-LLVY-AMC (Cat.# 10-2971, for assaying its chymotrypsin-like activity) and Z-LLE-AMC, (for determining its PGPH activity). Fluorogenic substrate. Ex.: 380nm Em.: 460nm.

Uses

Bz-Val-Gly-Arg-AMC is a bioactive compound used in assaying the degree of inhibition conferred by PS-341, a potent peptidylboronic acid with anticancer properties.

References

1) Gillardon?et al. (2007),?The 20S proteasome isolated from Alzheimer’s disease brain shows post-translational modifications but unchanged proteolytic activity; J. Neurochem.,?101?1483 2) Kim?et al. (2002),?Navigation inside a protease: substrate selection and product exit in tricorn protease from Thermoplasma acidophilum; J. Mol. Biol.,?324?1041 3) Dahlmann?et al. (2000),?Different proteasome subtypes in a single tissue exhibit different enzymatic properties; J. Mol. Biol.,?303?643 4) Lightcap?et al. (2000),?Proteasome inhibition measurements: clinical application; Clin. Chem.,?46?673

BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

87779-49-5, BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALTRelated Search:


  • N-[(2S)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]benzamide
  • BZ-VAL-GLY-ARG-AMC TFA SALT
  • BZ-VAL-GLY-ARG-AMC TRIFLUOROACETATE SALT
  • Bz-VGR-AMC
  • Bz-Val-Gly-Arg-AMC
  • L-Argininamide, N-benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
  • N-Benzoyl-L-valylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide
  • Bz-Val-Gly-Arg-AMC (I-1085.0050)
  • 87779-49-5
  • C30H37N7O6
  • Miscellaneous Enzyme