Isepamicine

Product Name: Isepamicine
CAS No.: 58152-03-7
Chemical Name: Isepamicine
Synonyms: hapa-b;sch21420;isepamicin;ISEPAMICINE;hapa-gentamycinb;ISEPAMICIN SULPHATE;Isepamicine USP/EP/BP;(s)-y-1-oxopropyl)-2-deoxy;Isepamicin Sulfate Impurity Ⅲ:Isepamicine;Isepamicin Sulfate Impurity Ⅲ:Isepamicine
CBNumber: CB3245233
Molecular Formula: C22H43N5O12
Formula Weight: 569.6
MOL File: 58152-03-7.mol

More

Less

Isepamicine Property

Boiling point:: 633.08°C (rough estimate)
Density: 1.3531 (rough estimate)
refractive index: 1.7500 (estimate)
pka: 11.01±0.35(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb134569
Product name: Isepamicin
Purity: >99%
Packaging: 100mg
Price: $510
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb134569
Product name: Isepamicin
Purity: >99%
Packaging: 250mg
Price: $765
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ING0005409
Product name: ISEPAMICIN
Purity: 95.00%
Packaging: 250MG
Price: $1146.05
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb134569
Product name: Isepamicin
Purity: >99%
Packaging: 1g
Price: $1504.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: ING0005409
Product name: ISEPAMICIN
Purity: 95.00%
Packaging: 1G
Price: $1758.49
Updated: 2021/12/16

More

Less

Isepamicine Chemical Properties,Usage,Production

Description

Isepamicin is a aminoglycoside antibiotic indicated for use in the treatment of urinary and respiratory tract infections. Although it is less potent than most other aminoglycosides, it is also less nephrotoxic. The broad-spectrum activity of isepamicin generally parallels that of amikacin in vitro.

Originator

Schering Plough (USA)

Uses

Antibacterial (aminoglyco side).

brand name

Isepacin; Exacin

Antimicrobial activity

Hydroxyamino propionyl gentamicin B. A semisynthetic derivative of gentamicin B, modified to render it more resistant to microbial inactivation.
In-vitro activity is comparable to or slightly greater than amikacin against Staph. aureus and most enterobacteria; it is much more active against Ser. marcescens, Enterobacter spp. and Klebsiebella pneumoniae. It is also active in vitro against the Mycobacterium avium complex and Nocardia asteroides. It is less susceptible than amikacin or gentamicin to inactivation by β-lactam antibiotics. It retains activity against some strains resistant to most other aminoglycosides.
Pharmacokinetics in neonatal, pediatric, adult, elderly and renally impaired patients are similar to those of other aminoglycosides. In adult volunteers the plasma half-life was 2.1 h. Clearance is reduced in neonates and the elderly. A 7.5 mg/kg once-daily dosage is recommended for children less than 16 days old. No dosage adjustment is required for the elderly unless renal function is impaired. Clearance is proportional to creatinine clearance in patients with chronic renal impairment, and it is eliminated by hemodialysis.
It has been used in respiratory tract infections, urinary tract infections and intra-abdominal infections, in adults and children. It appears to be as effective and well tolerated as amikacin. It is available in Japan.

Isepamicine Preparation Products And Raw materials

Raw materials

Ammonium hydroxide Trifluoroacetic acid Isepamicin sulfate

Preparation Products

More

Less

Isepamicine Suppliers

China 55 Europe 3 India 3 United Kingdom 4 United States 7 Global 72

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9958
Advantage: 58

Intelligence Pharm Science(Shanghai) Co., Ltd.

Tel: 021-57898186
Fax: 021-37699262
Country: China
ProdList: 449
Advantage: 55

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Chengdu MassCale Pharmaceutical Co., Ltd.

Tel: 028-84552636 18084815636
Email: chensfsc@126.com
Country: China
ProdList: 1445
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

More

Less

View Lastest Price from Isepamicine manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Isepamicine 58152-03-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: isepamicin 58152-03-7
Price: US $1.00/g
Min. Order: 1g
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-10

Career Henan Chemical Co

Product: Isepamicine 58152-03-7
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-10

58152-03-7, IsepamicineRelated Search:

6-Aminocaproic acid Tris(hydroxymethyl)aminomethane ALTRENOGEST Glycine Omeprazole magnesium Isepamicin sulfate Miboplatin 4-ACETAMIDOCYCLOHEXANOL GENTAMICIN B N-(3-AMINOPROPYL)CYCLOHEXYLAMINE (1R,2R)-2-(PROPYLAMINO)CYCLOHEXANOL (1R,2R)-2-(ETHYLAMINO)CYCLOHEXANOL METHYL 6-AMINO-6-DEOXY-GALACTOPYRANOSIDE 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine AMINO ACIDS Isepamicine METHYL 6-AMINO-6-DEOXY-GALACTOPYRANOSIDE Nojirimycin

(s)-y-1-oxopropyl)-2-deoxy

hapa-b

hapa-gentamycinb

4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabinopyranosyl]-N1-[(S)-3-amino-2-hydroxypropionyl]-2-deoxy-D-streptamine

Isepamicin Sulfate Impurity Ⅲ:Isepamicine

isepamicin

sch21420

thyl-3-(methylamino)-beta-l-arabinopyranosyl-(1-6))-n(sup1)-(3-amino-2-hydrox

ISEPAMICIN SULPHATE

(S)-O-6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1->6)]-1,3-diamino-N1-(3-aminolactoyl)-1,2,3-trideoxy-D-scyllo-inositol

D-Streptamine, O-6-amino-6-deoxy-a-D-glucopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)]-N1-(3-amino-2-hydroxy-1-oxopropyl)-2-deoxy-, (S)-

D-Streptamine, O-6-amino-6-deoxy-a-D-glucopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)]-N1-[(2S)-3-amino-2-hydroxy-1-oxopropyl]-2-deoxy- (9CI)

ISEPAMICINE

(2S)-3-Amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy-2-[(3R,4R,5R)-3,5-dihydroxy-5-methyl-4-methylaminooxan-2-yl]oxy-3-hydroxycyclohexyl]-2-hydroxypropanamide

(S)-O-6-Amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyrano-syl-(1→6)]-N^<1>^-(3-amino-2-hydroxy-1-oxopropyl)-2-deoxy-D-streptamine

4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-N1-[(S)-3-amino-2-hydroxy-1-oxopropyl]-2-deoxy-D-streptamine

4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-N1-[(S)-3-amino-2-hydroxypropanoyl]-2-deoxy-D-streptamine

D-Streptamine, O-6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-N1-[(2S)-3-amino-2-hydroxy-1-oxopropyl]-2-deoxy-

Isepamicine USP/EP/BP

(S)-O-6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1->6)]-1,3-diamino-N1-(3-aminolactoyl)-1,2,3-trideoxy-D-scyllo-inositol

Isepamicin Sulfate Impurity Ⅲ:Isepamicine

58152-03-7

C22H43N5O12