ChemicalBook > CAS DataBase List > (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
- Product Name
- (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
- CAS No.
- 72795-01-8
- Chemical Name
- (±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride
- Synonyms
- CS-769;ICI 118;551 hydrochloride;CI 118551 Hydrochloride;ICI 118,551 hydrochloride, >=98%;(2R,3R)-rel-1-[(2,3-Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride (1:1);(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride;ICI118551,ICI 118,551 hydrochloride,ICI 118551,Adrenergic Receptor,ICI-118551,Inhibitor,Beta Receptor,inhibit,ICI 118,551
- CBNumber
- CB32518939
- Molecular Formula
- C17H28ClNO2
- Formula Weight
- 313.87
- MOL File
- 72795-01-8.mol
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(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride Property
- storage temp.
- desiccated
- solubility
- DMSO : 25 mg/mL (79.65 mM; Need ultrasonic)H2O : 12.5 mg/mL (39.83 mM; Need ultrasonic)
- form
- powder
- color
- white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- I127
- Product name
- ICI 118,551 hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $263
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- I127
- Product name
- ICI 118,551 hydrochloride
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $934
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15591
- Product name
- ICI 118551 (hydrochloride)
- Purity
- ≥99%
- Packaging
- 10mg
- Price
- $145
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 15591
- Product name
- ICI 118551 (hydrochloride)
- Purity
- ≥99%
- Packaging
- 50mg
- Price
- $616
- Updated
- 2024/03/01
TRC
- Product number
- I163850
- Product name
- ICI 118,551 hydrochloride
- Packaging
- 5mg
- Price
- $140
- Updated
- 2021/12/16
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(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride Chemical Properties,Usage,Production
Description
ICI 118551 is a potent, selective antagonist of the β2-
Uses
ICI 118,551 hydrochloride has been used:
- to block β-adrenergic signaling in various experiments
- to counteract degradation by endogenous T-lymphocyte monoamine oxidases
- to determine the specific receptor subtype necessary for isoproterenol to induce up-regulation of gene transcripts
Uses
The (R,R)-enantiomer of ICI 118551 as highly selective β2-adrenoceptor antagonist. The S,S-enantiomer is the most potent.
Biochem/physiol Actions
ICI 118,551 has been used to treat vasomotor migraines and somatic troubles related to anxiety state.
storage
Store at RT
(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanolhydrochloride Suppliers
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