ChemicalBook > CAS DataBase List > (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine

Product Name
(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine
CAS No.
380499-07-0
Chemical Name
(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine
Synonyms
Desfluro Aprepitant;Aprepitant Impurity 6;Aprepitant Impurity 69;Aprepitant dehydro dealkyl;(R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine;(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine;2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-;(R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (Aprepitant Impurity)
CBNumber
CB32542880
Molecular Formula
C20H16F7NO2
Formula Weight
435.34
MOL File
380499-07-0.mol
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(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Property

solubility 
Chloroform, Ethyl Acetate
form 
Solid
color 
Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B657140
Product name
(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine
Packaging
1mg
Price
$155
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0002125
Product name
(2R)-2-[(1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY]-3-(4-FLUOROPHENYL)-5,6-DIHYDRO-2H-1,4-OXAZINE
Purity
95.00%
Packaging
5MG
Price
$502.61
Updated
2021/12/16
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(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of enantiomerically pure Aprepitant diastereomers and derivatives.

(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine Suppliers

Canada 1 China 28 India 1 United States 1 Global 31
Toronto Research Chemicals
Tel
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Fax
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Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

380499-07-0, (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazineRelated Search:

1,1,1-Trimethoxy-2-chloroethane ent-Aprepitant (2R,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride Aprepitant Impurity 9 Aprepitant Impurity 6 Aprepitant Impurity A Enantiomer 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Aprepitant Impurity 19 [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol Benzyl dihydrogen phosphate Aprepitant Fosaprepitant dimeglumine 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Fosaprepitant Impurity 5 (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Aprepitant Aprepitant Impurity 11 HCl

  • (2R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine
  • Aprepitant dehydro dealkyl
  • Desfluro Aprepitant
  • 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-
  • (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine
  • (R)-6-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine (Aprepitant Impurity)
  • Aprepitant Impurity 69
  • Aprepitant Impurity 6
  • 380499-07-0
  • C20H16F7NO2
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals