Isosorbide 5-mononitrate
- Product Name
- Isosorbide 5-mononitrate
- CAS No.
- 16051-77-7
- Chemical Name
- Isosorbide 5-mononitrate
- Synonyms
- ISOSORBIDE MONONITRATE;ISMN;Ismo;IMDUR;5-ismn;Vasotrate;5-ISOSORBIDE MONONITRATE;ELAN;Momt;Coronu
- CBNumber
- CB3256697
- Molecular Formula
- C6H9NO6
- Formula Weight
- 191.14
- MOL File
- 16051-77-7.mol
Isosorbide 5-mononitrate Property
- Melting point:
- 88-93 °C
- alpha
- 170 º (c=1, EtOH)
- Boiling point:
- 326.86°C (rough estimate)
- Density
- 1.5784 (rough estimate)
- refractive index
- 145 ° (C=5, H2O)
- storage temp.
- -20°C Freezer
- solubility
- Undiluted isosorbide mononitrate is freely soluble in water, in acetone, in ethanol (96 per cent) and in methylene chloride. The solubility of the diluted product depends on the diluent and its concentration.
- pka
- 13.09±0.40(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- soluble
- Merck
- 5225
- InChIKey
- YWXYYJSYQOXTPL-SLPGGIOYSA-N
- CAS DataBase Reference
- 16051-77-7(CAS DataBase Reference)
- EPA Substance Registry System
- D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate (16051-77-7)
Safety
- Hazard Codes
- Xi-F,Xi,F
- Risk Statements
- 36/37/38-11
- Safety Statements
- 37/39-16-15
- RIDADR
- 3251
- RTECS
- LZ4386500
- HazardClass
- 4.1
- HS Code
- 2932999000
- Toxicity
- LD50 oral in rat: 2010mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H228Flammable solid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
N-Bromosuccinimide Price
- Product number
- J63674
- Product name
- Isosorbide mononitrate, 98+%
- Packaging
- 5g
- Price
- $193.65
- Updated
- 2024/03/01
- Product number
- J63674
- Product name
- Isosorbide mononitrate, 98+%
- Packaging
- 10g
- Price
- $307.65
- Updated
- 2024/03/01
- Product number
- J63674
- Product name
- Isosorbide mononitrate, 98+%
- Packaging
- 25g
- Price
- $704.65
- Updated
- 2024/03/01
- Product number
- KIT8290
- Product name
- Isosorbide5-Mononitrate(1.0mg/mLinDimethylSulfoxide)
- Packaging
- 10x1mL
- Price
- $180
- Updated
- 2021/12/16
- Product number
- BICL4113
- Product name
- Isosorbide-5-mononitrate
- Purity
- 99%min
- Packaging
- 500mg
- Price
- $707
- Updated
- 2021/12/16
Isosorbide 5-mononitrate Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Uses
antidepressant, 5HT reuptake inhibitor
Uses
Isosorbide 5-Mononitrate is a metabolite of Isosorbide Dinitrate; used as an antianginal.
Uses
A metabolite of Isosorbide Dinitrate. Used as an antianginal
Definition
ChEBI: Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.
brand name
Imdur (Schering-Plough); Ismo (Dr. Reddy’s); Monoket (Schwarz Pharma) .
General Description
Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.
Air & Water Reactions
Highly flammable.
Reactivity Profile
The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.
Health Hazard
Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.
Fire Hazard
Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.
Clinical Use
Vasodilator:
Treatment and prophylaxis of angina
Adjunct in congestive heart failure
Isosorbide 5-mononitrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Isosorbide 5-mononitrate manufacturers
- Product
- Isosorbide 5-Mononitrate 16051-77-7
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-06
- Product
- isosorbide mononitrate 16051-77-7
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-06
- Product
- Isosorbide 5-mononitrate 16051-77-7
- Price
- US $65.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-27