Isosorbide 5-mononitrate

Product Name: Isosorbide 5-mononitrate
CAS No.: 16051-77-7
Chemical Name: Isosorbide 5-mononitrate
Synonyms: ISOSORBIDE MONONITRATE;ISMN;Ismo;IMDUR;5-ismn;Vasotrate;5-ISOSORBIDE MONONITRATE;ELAN;Momt;Coronu
CBNumber: CB3256697
Molecular Formula: C6H9NO6
Formula Weight: 191.14
MOL File: 16051-77-7.mol

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Isosorbide 5-mononitrate Property

Melting point:: 88-93 °C
alpha: 170 º (c=1, EtOH)
Boiling point:: 326.86°C (rough estimate)
Density: 1.5784 (rough estimate)
refractive index: 145 ° (C=5, H2O)
storage temp.: -20°C Freezer
solubility: Undiluted isosorbide mononitrate is freely soluble in water, in acetone, in ethanol (96 per cent) and in methylene chloride. The solubility of the diluted product depends on the diluent and its concentration.
pka: 13.09±0.40(Predicted)
form: Solid
color: White to Off-White
Water Solubility: soluble
Merck: 5225
InChIKey: YWXYYJSYQOXTPL-SLPGGIOYSA-N
CAS DataBase Reference: 16051-77-7(CAS DataBase Reference)
EPA Substance Registry System: D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate (16051-77-7)

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Safety

Hazard Codes: Xi-F,Xi,F
Risk Statements: 36/37/38-11
Safety Statements: 37/39-16-15
RIDADR: 3251
RTECS: LZ4386500
HazardClass: 4.1
HS Code: 2932999000
Toxicity: LD50 oral in rat: 2010mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

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N-Bromosuccinimide Price

Alfa Aesar

Product number: J63674
Product name: Isosorbide mononitrate, 98+%
Packaging: 5g
Price: $193.65
Updated: 2024/03/01

Alfa Aesar

Product number: J63674
Product name: Isosorbide mononitrate, 98+%
Packaging: 10g
Price: $307.65
Updated: 2024/03/01

Alfa Aesar

Product number: J63674
Product name: Isosorbide mononitrate, 98+%
Packaging: 25g
Price: $704.65
Updated: 2024/03/01

TRC

Product number: KIT8290
Product name: Isosorbide5-Mononitrate(1.0mg/mLinDimethylSulfoxide)
Packaging: 10x1mL
Price: $180
Updated: 2021/12/16

Apolloscientific

Product number: BICL4113
Product name: Isosorbide-5-mononitrate
Purity: 99%min
Packaging: 500mg
Price: $707
Updated: 2021/12/16

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Isosorbide 5-mononitrate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

antidepressant, 5HT reuptake inhibitor

Uses

Isosorbide 5-Mononitrate is a metabolite of Isosorbide Dinitrate; used as an antianginal.

Uses

A metabolite of Isosorbide Dinitrate. Used as an antianginal

Definition

ChEBI: Isosorbide mononitrate is a nitrate ester and a glucitol derivative. It has a role as a nitric oxide donor and a vasodilator agent.

brand name

Imdur (Schering-Plough); Ismo (Dr. Reddy’s); Monoket (Schwarz Pharma) .

General Description

Isosorbide 5-mononitrate is a crystalline solid. Isosorbide 5-mononitrate is very flammable and may be toxic by ingestion.

Air & Water Reactions

Highly flammable.

Reactivity Profile

The dinitrate, a heart drug, can detonate when dry, but is non explosive with 30% of water [J. Haz.. Mater., 1992, 32(1), 87]. The mononitrate would be expected to be less reactive.

Health Hazard

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished.

Clinical Use

Vasodilator:
Treatment and prophylaxis of angina
Adjunct in congestive heart failure

Isosorbide 5-mononitrate Preparation Products And Raw materials

Raw materials

D-Sorbitol Isosorbide dinitrate Sorbitol

Preparation Products

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Isosorbide 5-mononitrate Suppliers

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View Lastest Price from Isosorbide 5-mononitrate manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Isosorbide 5-Mononitrate 16051-77-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-06

Hebei Yanxi Chemical Co., Ltd.

Product: isosorbide mononitrate 16051-77-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20 tons
Release date: 2023-09-06

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Isosorbide 5-mononitrate 16051-77-7
Price: US $65.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-27

16051-77-7, Isosorbide 5-mononitrateRelated Search:

Isosorbide Isosorbide dinitrate ISOSORBIDE 2-MONONITRATE,ISOSORBIDE 2-MONONITRATE 99-101.0% Sodium hydride NIVITIN DEHYDROGENASE Sorbitol Prenyl acetate isosorbide-5-mononitrate-2-glucuronide ISOSORBIDE-13C6 DINITRATE Isosorbide 5-mononitrate

IMDUR

IS-5-MN

ISOSORBIDE MONONITRATE

ISOSORBIDE 5-MONONITRATE

ISOSORBIDE 5-NITRATE

ELANTAN

ELAN

CORANGIN

5-ISOSORBIDE MONONITRATE

MONOSORB

MONOCEDOCARD

MONOCLAIR

1,4:3,6-dianhydro-,5-nitrate,d-glucito

1,4:3,6-dianhydro-d-glucito5-nitrate

1,4:3,6-dianhydro-d-glucitol5-nitrate

1,4:3,6-DIANHYDRO-D-GLUCITOL 5-MONONITRATE

6-Nitrooxy-hexahydro-furo[3,2-β]furan-3-ol

6-Nitrooxy-hexahydro-furo[3,2-b]furan-3-ol

D-Glucitol, 1,4:3,6-dianhydro-, 5-nitrate

[(1R,2R,5R,6S)-6-hydroxy-4,8-dioxabicyclo[3.3.0]oct-2-yl] nitrate

ISOSORBIDE MONO ACETATE

5-ismn

ahr4698

bm22-145

Ososoribide-5-mononitrate

ISOSORBIDE 5-MONONITRATE, 98.5%

Corangin,Elan,Elantan,Imdur,Monocedocard,Monoclair,Monosorb

1,4:3,6-Dianhydro-D-glucitol mononitrate

1,4:3,6-Dianhydro-D-glucitd 5-mononitrate

Vasotrate

ISOSORBIDE MONONITRATE(ISOSORBIDE-5-MONONITRATE)

isosorbide 5-mononitrite

Erlotinib-d17 HCl

Diluted Isosorbide Mononitrate (50%)

1,4:3,6-Dianhydro-5-O-nitro-D-erythro-hexitol

IS-5-MN (ISOSORBIDE-5-MONONITRATE

(3S,3aS,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate

Isosorbide-5-mononitrate min. 99%

Isosorbide Mononitrate EP

Coronu

Ismo

Isomonat

Momt

Monicor

Olicard

[(3R,3aS,6S,6aR)-6-hydroxy-2,3,3a,5,6,6a-hexahydrofuro[2,3-d]furan-3-yl nitrate

5-Nitro-1,4,3,6-dianhydro-D-glucitol

6-Nitroxoyhexahydrofuro[3,2-b]furan-3-ol

8-Nitrooxy-2,6-dioxabicyclo[3.3.0]octan-4-ol

ISMN

TY-10368

Isosorbide mononitrate,contains ~30%(w/w) lactose

(3R,3aS,6S,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl nitrate

Diluted Isosorbide Mononitrate (750 mg)

Isosorbide 5-Mononitrate (1.0 mg/mL in Dimethyl Sulfoxide)

Isosorbide5-Nitrate&gt

Isosorbide mononitrate CRS

Monoket