7-Methoxy-1,2,3,4-tetrahydroquinoline
- Product Name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- CAS No.
- 19500-61-9
- Chemical Name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- Synonyms
- 1,2,3,4-tetrahydro-7-methoxyQuinoline;Quinoline, 1,2,3,4-tetrahydro-7-methoxy-
- CBNumber
- CB32651926
- Molecular Formula
- C10H13NO
- Formula Weight
- 163.22
- MOL File
- 19500-61-9.mol
7-Methoxy-1,2,3,4-tetrahydroquinoline Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Appearance
- Colorless to light yellow Liquid
N-Bromosuccinimide Price
- Product number
- M845270
- Product name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- M845270
- Product name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- M845270
- Product name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- Packaging
- 50mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- P000475798
- Product name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- P000475798
- Product name
- 7-Methoxy-1,2,3,4-tetrahydroquinoline
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $142
- Updated
- 2021/12/16
7-Methoxy-1,2,3,4-tetrahydroquinoline Chemical Properties,Usage,Production
Synthesis
4964-76-5
19500-61-9
General procedure for the synthesis of 7-methoxy-1,2,3,4-tetrahydroquinoline from 7-methoxyquinoline: platinum oxide (PtO2, 180 mg, 0.79 mmol) was added to a methanol (60 mL) solution of 7-methoxyquinoline (2.0 g, 12.56 mmol). Hydrogen (H2) was passed into the above solution at room temperature and the reaction mixture was stirred overnight. Upon completion of the reaction, the solid catalyst was removed by filtration. The filtrate was concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography using a petroleum ether solution of 3% ethyl acetate as eluent to afford 7-methoxy-1,2,3,4-tetrahydroquinoline as a light yellow oil (1.5 g). Mass spectrum (M + H)+ m/z: 164.0. 1H-NMR (300 MHz, CD3OD) δ: 6.76 (d, J = 8.4 Hz, 1H), 6.09-6.17 (m, 2H), 3.69 (s, 3H), 3.19-3.23 (m, 2H), 2.64-2.69 (t, J = 6.6 Hz, 2H), 1.85 -1.93 (m, 2H).
References
[1] Patent: WO2012/58125, 2012, A1. Location in patent: Page/Page column 115; 116
[2] Patent: WO2012/94462, 2012, A2. Location in patent: Page/Page column 83
[3] Patent: WO2016/86200, 2016, A1. Location in patent: Page/Page column 278
[4] Farmaco, Edizione Scientifica, 1954, vol. 9, p. 205,209
[5] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 13, p. 3415 - 3418
7-Methoxy-1,2,3,4-tetrahydroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
7-Methoxy-1,2,3,4-tetrahydroquinoline Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 7-Methoxy-1,2,3,4-tetrahydroquinoline manufacturers
- Product
- 7-Methoxy-1,2,3,4-tetrahydroquinoline 19500-61-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- g/kg/T
- Release date
- 2019-12-18