ChemicalBook > CAS DataBase List > H2N-PEG5-CH2COOH

H2N-PEG5-CH2COOH

Product Name
H2N-PEG5-CH2COOH
CAS No.
141282-35-1
Chemical Name
H2N-PEG5-CH2COOH
Synonyms
Amino-PEG5;NH2-PEG5-CH2COOH;H2N-PEG5-CH2COOH;Amino-PEG5-CH2COOH;Amino-PEG5-CH2CO5H;Amino-PEG5-CH2CO2H;AMINE-PEG5-CH2COOH;Amino-PEG5-acetic acid;Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]aceticacid
CBNumber
CB32656921
Molecular Formula
C12H25NO7
Formula Weight
295.33
MOL File
141282-35-1.mol
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H2N-PEG5-CH2COOH Property

Boiling point:
434.2±40.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
solubility 
DMSO : 20 mg/mL (67.72 mM; ultrasonic and warming and heat to 60°C)
form 
Solid
pka
3.39±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A619535
Product name
Amino-PEG5-CH2CO2H
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
A619535
Product name
Amino-PEG5-CH2CO2H
Packaging
50mg
Price
$130
Updated
2021/12/16
TRC
Product number
A619535
Product name
Amino-PEG5-CH2CO2H
Packaging
100mg
Price
$220
Updated
2021/12/16
BroadPharm
Product number
BP-22065
Product name
Amino-PEG5-CH2CO2H
Purity
98%
Packaging
1g
Price
$450
Updated
2021/12/16
Activate Scientific
Product number
AS104135
Product name
H2N-PEG5-CH2COOH
Purity
95+%
Packaging
1g
Price
$588
Updated
2021/12/16
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H2N-PEG5-CH2COOH Chemical Properties,Usage,Production

Uses

Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

H2N-PEG5-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H2N-PEG5-CH2COOH manufacturers

LAURENT
Product
NH2-PEG5-CH2COOH 141282-35-1
Price
US $433.00/g
Min. Order
1g
Purity
98%
Supply Ability
200kg
Release date
2025-11-17
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Amino-PEG5-CH2CO2H 141282-35-1
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-05
Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG5-CH2COOH 141282-35-1
Price
US $0.00/mg
Min. Order
250mg
Purity
>98.00%
Supply Ability
250mg
Release date
2024-03-22

141282-35-1, H2N-PEG5-CH2COOHRelated Search:

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  • H2N-PEG5-CH2COOH
  • Amino-PEG5-CH2CO2H
  • Amino-PEG5-acetic acid
  • AMINE-PEG5-CH2COOH
  • NH2-PEG5-CH2COOH
  • Amino-PEG5-CH2COOH
  • Amino-PEG5
  • Amino-PEG5-CH2CO5H
  • 2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]aceticacid
  • H2N-PEG5-CH2COOH/Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • 141282-35-1
  • peg