ChemicalBook > CAS DataBase List > H2N-PEG5-CH2COOH

H2N-PEG5-CH2COOH

Product Name
H2N-PEG5-CH2COOH
CAS No.
141282-35-1
Chemical Name
H2N-PEG5-CH2COOH
Synonyms
Amino-PEG5;NH2-PEG5-CH2COOH;H2N-PEG5-CH2COOH;Amino-PEG5-CH2COOH;Amino-PEG5-CH2CO5H;Amino-PEG5-CH2CO2H;AMINE-PEG5-CH2COOH;Amino-PEG5-acetic acid;Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-;2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]aceticacid
CBNumber
CB32656921
Molecular Formula
C12H25NO7
Formula Weight
295.33
MOL File
141282-35-1.mol
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H2N-PEG5-CH2COOH Property

Boiling point:
434.2±40.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
solubility 
DMSO : 20 mg/mL (67.72 mM; ultrasonic and warming and heat to 60°C)
form 
Solid
pka
3.39±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A619535
Product name
Amino-PEG5-CH2CO2H
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
A619535
Product name
Amino-PEG5-CH2CO2H
Packaging
50mg
Price
$130
Updated
2021/12/16
TRC
Product number
A619535
Product name
Amino-PEG5-CH2CO2H
Packaging
100mg
Price
$220
Updated
2021/12/16
BroadPharm
Product number
BP-22065
Product name
Amino-PEG5-CH2CO2H
Purity
98%
Packaging
1g
Price
$450
Updated
2021/12/16
Activate Scientific
Product number
AS104135
Product name
H2N-PEG5-CH2COOH
Purity
95+%
Packaging
1g
Price
$588
Updated
2021/12/16
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H2N-PEG5-CH2COOH Chemical Properties,Usage,Production

Biological Activity

Amino-PEG5-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

H2N-PEG5-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from H2N-PEG5-CH2COOH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG5-CH2COOH 141282-35-1
Price
US $0.00/mg
Min. Order
250mg
Purity
>98.00%
Supply Ability
250mg
Release date
2024-03-22
Career Henan Chemical Co
Product
H2N-PEG5-CH2COOH 141282-35-1
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-21

141282-35-1, H2N-PEG5-CH2COOHRelated Search:


  • H2N-PEG5-CH2COOH
  • Amino-PEG5-CH2CO2H
  • Amino-PEG5-acetic acid
  • AMINE-PEG5-CH2COOH
  • NH2-PEG5-CH2COOH
  • Amino-PEG5-CH2COOH
  • Amino-PEG5
  • Amino-PEG5-CH2CO5H
  • 2-(2-{2-[2-(2-amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]aceticacid
  • H2N-PEG5-CH2COOH/Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • Acetic acid, 2-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-
  • 141282-35-1
  • peg