ChemicalBook > CAS DataBase List > Methyl 4-aminobenzoate

Methyl 4-aminobenzoate

Product Name
Methyl 4-aminobenzoate
CAS No.
619-45-4
Chemical Name
Methyl 4-aminobenzoate
Synonyms
Tetracaine Impurity 1;4-carbomethoxyaniline;p-Aminobenzoic acid methyl ester;h-4-abz-ome;TIMTEC-BB SBB004063;Benzocaine impurity H;Tetracaine Impurity 4;METHYL 4-AMINOBENZOATE;METHYL P-AMINOBENZOATE;LABOTEST-BB LTBB000528
CBNumber
CB3269934
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
619-45-4.mol
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Methyl 4-aminobenzoate Property

Melting point:
110-111 °C (lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
3.82g/l
form 
Crystals or Crystalline Powder
pka
pK1:2.38(＋1) (25°C)
color 
White to beige
Water Solubility 
Soluble in alcohol and ether. Slightly soluble in water.
BRN 
775913
InChIKey
LZXXNPOYQCLXRS-UHFFFAOYSA-N
LogP
1.370
CAS DataBase Reference
619-45-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, 4-amino-, methyl ester(619-45-4)
EPA Substance Registry System
Benzoic acid, 4-amino-, methyl ester (619-45-4)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-36/37/39
WGK Germany 
3
RTECS 
DG2900000
TSCA 
Yes
HS Code 
29224995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
274186
Product name
Methyl 4-aminobenzoate
Purity
98%
Packaging
5g
Price
$46.8
Updated
2024/03/01
Sigma-Aldrich
Product number
274186
Product name
Methyl 4-aminobenzoate
Purity
98%
Packaging
25g
Price
$99.5
Updated
2024/03/01
TCI Chemical
Product number
A0510
Product name
Methyl 4-Aminobenzoate
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$59
Updated
2024/03/01
TCI Chemical
Product number
A0510
Product name
Methyl 4-Aminobenzoate
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$317
Updated
2022/04/27
Alfa Aesar
Product number
A11715
Product name
Methyl 4-aminobenzoate, 98%
Packaging
25g
Price
$60.65
Updated
2024/03/01
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Methyl 4-aminobenzoate Chemical Properties,Usage,Production

Chemical Properties

white to beige crystals or crystalline powder

Uses

Methyl 4-aminobenzoate is used in the synthesis of guanidine alkaloids, (±)-martinelline and (±)-martinellic acid by a protic acid catalyzed hetero Diels-Alder coupling reaction with N-Cbz 2-pyrroline. It is also used in organic synthesis and acts as a dye intermediate. Further, it is used to prepare 4-(2-methyl-4-oxo-4H-quinazolin-3-yl)-benzoic acid methyl ester by reacting with 2-acetylamino-benzoic acid.

Uses

Methyl 4-aminobenzoate was used in the syntheses of guanidine alkaloids, (±)-martinelline and (±)-martinellic acid by a protic acid catalyzed hetero Diels-Alder coupling reaction with N-Cbz 2-pyrroline.

Synthesis Reference(s)

Synthetic Communications, 26, p. 973, 1996 DOI: 10.1080/00397919608003701
Synthesis, p. 23, 1978

General Description

The catalytic oxidation of methyl 4-aminobenzoate by hydrogen peroxide was studied.

Methyl 4-aminobenzoate Preparation Products And Raw materials

Raw materials

4-Aminobenzoic acid 4-Nitrobenzoic acid Ethyl acetate Hydrochloric acid Methanol Esterified product Thionyl chloride PETROLEUM ETHER Sodium carbonate

Preparation Products

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Methyl 4-aminobenzoate Suppliers

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View Lastest Price from Methyl 4-aminobenzoate manufacturers

Hebei Saisier Technology Co., LTD
Product
Methyl 4-aminobenzoate 619-45-4
Price
US $6.00/KG
Min. Order
1KG
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-25
Henan Fengda Chemical Co., Ltd
Product
4-aminobenzoic acid methyl ester 619-45-4
Price
US $6.00-0.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-18
Hebei Jingbo New Material Technology Co., Ltd
Product
Methyl 4-aminobenzoate 619-45-4
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20000
Release date
2023-12-27

619-45-4, Methyl 4-aminobenzoateRelated Search:

Trimethoxymethane Methyl formate 4-Aminobenzoic acid P-AMINOBENZOIC ACID POTASSIUM SALT Methyl acrylate Methyl acetate tert-Butyl 4-aminobenzoate METHYL THIOPHENE-2-CARBOXYLATE Methylparaben p-Anisidine Thiophanate-methyl Methyl 2-bromobenzoate Methyl benzoate Methyl 4-cyanobenzoate Sulfanilic acid Bensulfuron methyl Kresoxim-methyl Metaclazepam

  • benzoicacid,4-amino-,methylester
  • Methyl aniline-4-carboxylate
  • Methyl ester of 4-aminobenzoic acid
  • Methyl ester of p-Aminobenzoic acid
  • methylaniline-4-carboxylate
  • p-(Methoxycarbonyl)aniline
  • p-Aminobenzoic acid methyl ester
  • p-aminobenzoicacidmethylester
  • p-amino-benzoicacimethylester
  • 4-AMINOBENZOIC ACID METHYL ESTER
  • 4-AMINO METHYL BENZOATE
  • METHYL 4-AMINOBENZOATE
  • METHYL P-AMINOBENZOATE
  • METHY-4-AMINO-BENZOIC ACID
  • Tetracaine Impurity 1
  • 4-amino-2-methylbenzoate
  • Benzocaine Impurity 8（Benzocaine EP Impurity H）
  • Methyl 4-aminobenzoate ,98%
  • 4-Aminobenzoic acid methyl
  • p-Aminobenzoic acid methyl
  • 4-(carbomethoxyl)aniline
  • 4-(Methoxycarbonyl)aniline
  • 4-amino-benzoicacimethylester
  • 4-carbomethoxyaniline
  • Benzoic acid, p-amino-, methyl ester
  • Methyl 4-aMinobenzoate, 98% 25GR
  • 4-AMinobenzenecarboxylic Acid Methyl Ester
  • Methyl 4-AMinophenylcarboxylate
  • Methyl 4-aminobenzoate 98%
  • TIMTEC-BB SBB004063
  • LABOTEST-BB LTBB000528
  • Benzoic acid, 4-amino-, methyl ester (9CI)
  • h-4-abz-ome
  • METHYL-PARA-AMINOBENZOATE
  • Benzocaine impurity H
  • Tetracaine Impurity 4
  • Benzocaine EP Impurity H
  • Methyl 4-Aminobenzoate &gt
  • Benzocaine EP Impurity H (Methyl 4-aminobenzoate)
  • Methyl 4-aminobenzoate USP/EP/BP
  • Methyl 4-aminobenzoate 619-45-4
  • 4-Amino Benzoic Acid, Methyl Ester (Methyl 4-Aminobenzoate)
  • Benzocaine Impurity H (BP)
  • Methyl 4-aminobenzoate,NA
  • 619-45-4
  • NH2C6H4COOCH3
  • H2NC6H4CO2CH3
  • Building Blocks
  • Carbonyl Compounds
  • C8 to C9
  • Aromatic Amino Acids
  • Unnatural Amino Acid Derivatives
  • Esters
  • Organic Building Blocks
  • Peptide Synthesis
  • Specialty Synthesis
  • Aromatic Esters
  • C8 to C9