Mosapride

Product Name: Mosapride
CAS No.: 112885-41-3
Chemical Name: Mosapride
Synonyms: Moza;Mosapid;TAK-370;Mosid-MT;MOSAPRIDE;Mosapride reference;Mosapride USP/EP/BP;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE;4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE
CBNumber: CB3273304
Molecular Formula: C21H25ClFN3O3
Formula Weight: 421.89
MOL File: 112885-41-3.mol

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Mosapride Property

Melting point:: 151-153°C
Boiling point:: 549.2±50.0 °C(Predicted)
Density: 1.272±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 13.52±0.46(Predicted)
color: White to Off-White
CAS DataBase Reference: 112885-41-3(CAS DataBase Reference)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M731000
Product name: Mosapride
Packaging: 100mg
Price: $215
Updated: 2021/12/16

Usbiological

Product number: M4676-20
Product name: Mosapride
Packaging: 10mg
Price: $382
Updated: 2021/12/16

Usbiological

Product number: 282965
Product name: Mosapride
Packaging: 50g
Price: $921
Updated: 2021/12/16

ApexBio Technology

Product number: B1059
Product name: Mosapride
Packaging: 10mg
Price: $55
Updated: 2021/12/16

AK Scientific

Product number: M687
Product name: Mosapride
Packaging: 50mg
Price: $162
Updated: 2021/12/16

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Mosapride Chemical Properties,Usage,Production

Description

Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.

Chemical Properties

White to Off-White Crystalline Solid

Originator

Dainippon (Japan)

Uses

A selective 5-HT4 receptor agonist. Gastroprokinetic.

Uses

gastroprokinetic agent

Definition

ChEBI: Mosapride is a racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying. It has a role as a gastrointestinal drug and a serotonergic agonist. It contains a (R)-mosapride and a (S)-mosapride.

brand name

Gasmotin

Hazard

A poison by ingestion.

Safety Profile

A poison by ingestion. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.

Mosapride Preparation Products And Raw materials

Raw materials

Preparation Products

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Mosapride Suppliers

Canada 1 China 152 Europe 2 Germany 1 India 4 United Kingdom 5 United States 32 Global 197

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View Lastest Price from Mosapride manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Mosapride 112885-41-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Mosapride 112885-41-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: Mosapride 112885-41-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

112885-41-3, MosaprideRelated Search:

4-AMINO-5-CHLORO-2-ETHOXY-N-[[4-(4-FLUOROBENZYL)-2-MORPHOLINYL]METHYL]BENZAMIDE CITRATE DIHYDRATE Mosapride Impurity 3 Mosapride Impurity 6 Mosapride Impurity 7 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide Mosapride Impurity 8 Mosapride Impurity 2 Mosapride Citric Amide Mosapride N-Oxide Des-4-fluorobenzyl Mosapride-d5 Mosapride Impurity 4 Mosapride Lactose Conjugate Mosapride Impurity 1 5-Amino-4-chloro-2-methylphenol 3-Hydroxyazetidine hydrochloride 2-(4-FLUOROBENZYLAMINO)ETHANOL 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE

4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE

4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE

4-AMINO-5-CHLORO-2-ETHOXY-N-[[[4-(4-FLUOROPHENYL)METHYL]-2-MORPHOLINYL]METHYL]-BENZAMIDE

((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride

4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide/Mosapride

MOSAPRIDE

Mosapride reference

Mosapride/4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)Benzamide

Mosapid

Mosid-MT

Moza

BenzaMide,4-aMino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)Methyl]-2-Morpholinyl]Methyl]-

TAK-370

Mosapride USP/EP/BP

Mosapride-FreebaseQ: What is Mosapride-Freebase Q: What is the CAS Number of Mosapride-Freebase Q: What is the storage condition of Mosapride-Freebase Q: What are the applications of Mosapride-Freebase

112885-41-3

12885-41-3

112885-41-5

C21H25ClFN3O3

API

TAK-370, AS-4370, Gasmotin

Pharmaceutical Intermediates

Amines

Aromatics

Agonist

Intermediates & Fine Chemicals

Pharmaceuticals

Agro Products