SPERMINE TETRAHYDROCHLORIDE
- Product Name
- SPERMINE TETRAHYDROCHLORIDE
- CAS No.
- 306-67-2
- Chemical Name
- SPERMINE TETRAHYDROCHLORIDE
- Synonyms
- NEURIDINE HYDROCHLORIDE;MUSCULAMINE HYDROCHLORIDE;Spermidine Tetrahydrochloride;Spermine4HCl;SPERMINE HCL;SperMine tetra;Spermine, TetraHCl;Spermine-[2H8].4HCl;4-BUTANEDIAMINE 4 HCL;SPERMINE HYDROCHLORIDE
- CBNumber
- CB3275333
- Molecular Formula
- C10H30Cl4N4
- Formula Weight
- 348.18
- MOL File
- 306-67-2.mol
SPERMINE TETRAHYDROCHLORIDE Property
- Melting point:
- 310-311 °C (dec.)(lit.)
- Density
- 1.01 g/mL at 20 °C
- storage temp.
- room temp
- solubility
- H2O: 1 M at 20 °C, clear, colorless
- form
- powder
- color
- White to Almost white
- PH
- 4.5-7.0 (25℃, 1M in H2O)
- Water Solubility
- Soluble in water (348.2 g/L at 20°C).
- λmax
- λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.15 - BRN
- 3911771
- InChI
- InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
- InChIKey
- XLDKUDAXZWHPFH-UHFFFAOYSA-N
- SMILES
- C(CNCCCN)CCNCCCN.Cl.Cl.Cl.Cl
- CAS DataBase Reference
- 306-67-2(CAS DataBase Reference)
- EPA Substance Registry System
- Spermine tetrahydrochloride (306-67-2)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 5677
- Product name
- Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem
- Packaging
- 5G
- Price
- $318
- Updated
- 2024/03/01
- Product number
- B1468
- Product name
- N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 5g
- Price
- $178
- Updated
- 2024/03/01
- Product number
- B1468
- Product name
- N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 25g
- Price
- $827
- Updated
- 2024/03/01
- Product number
- J63060
- Product name
- Spermine tetrahydrochloride, 99%
- Packaging
- 1g
- Price
- $35.6
- Updated
- 2024/03/01
- Product number
- J63060
- Product name
- Spermine tetrahydrochloride, 99%
- Packaging
- 5g
- Price
- $132
- Updated
- 2024/03/01
SPERMINE TETRAHYDROCHLORIDE Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Uses
Spermine Tetrahydrochloride is an inhibitor of NOS1, NMDA, GluR, and PLCα. A useful reactant for Surface-?enhanced Raman spectroscopy (SERS) characterization of abasic sites in DNA duplexes.
Uses
Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors and red blood cells of chicken.
Uses
Used to precipitate DNA from low salt aqueous buffers.
Biological Activity
Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.
Biochem/physiol Actions
Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
storage
Desiccate at +4°C
Purification Methods
Its pK values are similar to those of spermidine above. Purify it as for spermidine trihydrochloride above. [Beilstein 4 IV 1301.]
SPERMINE TETRAHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
SPERMINE TETRAHYDROCHLORIDE Suppliers
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View Lastest Price from SPERMINE TETRAHYDROCHLORIDE manufacturers
- Product
- spermine tetrahydrochloride 306-67-2
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%-99%
- Supply Ability
- Inquiry
- Release date
- 2023-06-25
- Product
- spermine tetrahydrochloride 306-67-2
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30
- Product
- Spermine Tetrahydrochloride 306-67-2
- Price
- US $60.00-23.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-14