ChemicalBook > CAS DataBase List > SPERMINE TETRAHYDROCHLORIDE

SPERMINE TETRAHYDROCHLORIDE

Product Name: SPERMINE TETRAHYDROCHLORIDE
CAS No.: 306-67-2
Chemical Name: SPERMINE TETRAHYDROCHLORIDE
Synonyms: NEURIDINE HYDROCHLORIDE;MUSCULAMINE HYDROCHLORIDE;Spermidine Tetrahydrochloride;Spermine4HCl;SPERMINE HCL;SperMine tetra;Spermidine 4HCl;Spermine, TetraHCl;Spermine-[2H8].4HCl;4-BUTANEDIAMINE 4 HCL
CBNumber: CB3275333
Molecular Formula: C10H30Cl4N4
Formula Weight: 348.18
MOL File: 306-67-2.mol

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SPERMINE TETRAHYDROCHLORIDE Property

Melting point:: 310-311 °C (dec.)(lit.)
Density: 1.01 g/mL at 20 °C
storage temp.: room temp
solubility: H₂O: 1 M at 20 °C, clear, colorless
form: powder
color: White to Almost white
PH: 4.5-7.0 (25℃, 1M in H2O)
biological source: synthetic
Water Solubility: Soluble in water (348.2 g/L at 20°C).
λmax: λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.15
BRN: 3911771
InChI: InChI=1S/C10H26N4.4ClH/c11-5-3-9-13-7-1-2-8-14-10-4-6-12;;;;/h13-14H,1-12H2;4*1H
InChIKey: XLDKUDAXZWHPFH-UHFFFAOYSA-N
SMILES: C(CNCCCN)CCNCCCN.Cl.Cl.Cl.Cl
CAS DataBase Reference: 306-67-2(CAS DataBase Reference)
EPA Substance Registry System: Spermine tetrahydrochloride (306-67-2)

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: EJ7230000
F: 3-10
TSCA: Yes
HS Code: 29212900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5677
Product name: Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem
Packaging: 5G
Price: $327
Updated: 2025/07/31

Sigma-Aldrich

Product number: 137141
Product name: Spermine tetrahydrochloride
Purity: EMPROVE? EVOLVE
Packaging: 25g
Price: $3295
Updated: 2025/07/31

Sigma-Aldrich

Product number: 137141
Product name: Spermine tetrahydrochloride
Purity: EMPROVE? EVOLVE
Packaging: 100g
Price: $10516
Updated: 2025/07/31

TCI Chemical

Product number: P2950
Product name: Spermine Tetrahydrochloride [for Protein Research]
Packaging: 1G
Price: $66
Updated: 2025/07/31

TCI Chemical

Product number: B1468
Product name: N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride
Purity: >98.0%(N)(T)
Packaging: 5g
Price: $178
Updated: 2025/07/31

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SPERMINE TETRAHYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Spermine Tetrahydrochloride is an inhibitor of NOS1, NMDA, GluR, and PLCα. A useful reactant for Surface-?enhanced Raman spectroscopy (SERS) characterization of abasic sites in DNA duplexes.

Uses

Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors and red blood cells of chicken.

Uses

Used to precipitate DNA from low salt aqueous buffers.

Biological Activity

Polyamine which produces a variety of modulatory effects on the NMDA receptor channel, acting through a specific site on the complex which can cause both agonist and antagonist effects.

Biochem/physiol Actions

Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).

storage

Desiccate at +4°C

Purification Methods

Its pK values are similar to those of spermidine above. Purify it as for spermidine trihydrochloride above. [Beilstein 4 IV 1301.]

SPERMINE TETRAHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SPERMINE TETRAHYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Spermine tetrahydrochloride 306-67-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1MT
Release date: 2025-09-12

Shaanxi Xianhe Biotech Co., Ltd

Product: Spermine Tetrahydrochloride (SPT) 306-67-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-28

Hebei Chuanghai Biotechnology Co., Ltd

Product: Spermine Tetrahydrochloride 306-67-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-28

306-67-2, SPERMINE TETRAHYDROCHLORIDERelated Search:

Methotrexate L-Lysine hydrochloride Betaine hydrochloride Dimethylamine hydrochloride polyethyleneimine 1-(5-Amino-4-bromo-2-chloro-phenyl)-ethanone Trichlormethiazide Zinc stearate 1,4-DIAMINOBUTANE O,O-Dimethyl phosphoramidothioate SPERMINE TETRAHYDROCHLORIDE SPERMINE TETRAHYDROCHLORIDE 1,3-DIAMINOPROPANE DIHYDROCHLORIDE 1,4-Diaminobutane dihydrochloride Spermidine Spermidine trihydrochloride Dipentene N-METHYL-BUTANE-1,4-DIAMINE 2HCL

N,N'-BIS(3-AMINOPROPYL)-BUTANE-1,4-DIAMINE TETRAHYDROCHLORIDE

N,N'-BIS(3-AMINOPROPYL)-1,4-BUTANEDIAMINE 4 H CL

N,N'-BIS-(3-AMINOPROPYL)-1,4-DIAMINOBUTANE TETRAHYDROCHLORIDE

NEURIDINE HYDROCHLORIDE

NEURIDINE TETRAHYDROCHLORIDE

MUSCULAMINE HYDROCHLORIDE

MUSCULAMINE TETRAHYDROCHLORIDE

SPERMINE HYDROCHLORIDE

SPERMINE TETRAHYDROCHLORIDE

DIAMINOPROPYLTETRAMETHYLENEDIAMINE HYDROCHLORIDE

GERONTINE TETRAHYDROCHLORIDE

1,4-BIS(AMINOPROPYL)BUTANEDIAMINE TETRAHYDROCHLORIDE

1,4-Butanediamine,N,N’-bis(3-aminopropyl)-,tetrahydrochloride

n1,n4-bis(3-aMinopropyl)-1,4-butanediaMine hydrochloride

N1,N1'-(butane-1,4-diyl)bis(propane-1,3-diaMine) tetrahydrochloride

SperMine tetra

Spermine tetrahydrochloride solution

Spermine tetrahydrochloride Vetec(TM) reagent grade

<i>N</i>,<i>N</i>'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride

SPERMINE TETRAHYDROCHLORIDE BIOREAGE

SPERMINE TETRAHYDROCHLORIDE BIOULTRA

Spermine tetrahydrochloride≥ 99% (GC)

Spermine Tetra HCl salt

4-butanediamine,n,n’-bis(3-aminopropyl)-tetrahydrochloride

4,9-diazoniadodecamethylenediammonium tetrachloride

Spermine, TetraHCl

SPERMINE TETRAHYDROCHLORIDE MOLECULAR*BI OLOGY REAGE

SPERMINE TETRAHYDROCHLORIDE, F. MOLE-CUL AR BIOLOGY

Spermine tetrahydrochloride 0.1 M Solution

Spermine4HCl

Additive Screening Solution 31/Fluka kit no 78374, Spermine tetrahydrochloride solution

additive screening solution 31/fluka kit no 78374

SPERMINETETRAHYDROCHLORIDE,BIOTECHGRADE

SPERMINE HCL

Spermine tetrahydrochloride,N,N′-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride

Spermine-[2H8].4HCl

NEURIDINE HYDROCHLORI

1,4-Butanediamine,N1,N4-bis(3-aminopropyl)-, hydrochloride (1:4)

Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem

)-1,4-butanediamine TetrahydrochL

N,N'-Bis(3-aminopropyL

N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride &gt

Spermidine Tetrahydrochloride

Spermine Tetrahydrochloride extrapure, 99%

Spermine tetrahydrochloride（SPT）

4-BUTANEDIAMINE 4 HCL

N,N'-Bis(3-aminopropyl)-1,4-butanediamine Tetrahydrochloride

Spermidine 4HCl

Spermine tetrahydrochloride, polyamine used for precipitation of DNA

Gadobutrol Impurity 180

SPERMISPERMINE TETRAHYDROCHLORIDENE TETRAHYDROCHLORIDE

306-67-2

C10H26N44HCl

C10H30Cl4N4

C10H26N44ClH

C10H26N4HCl

C10H30N6O2Cl4

C10H20N44HCl