ChemicalBook > CAS DataBase List > BC 11-38
BC 11-38
- Product Name
- BC 11-38
- CAS No.
- 686770-80-9
- Chemical Name
- BC 11-38
- Synonyms
- 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one;3-phenyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one;Thieno[3,2-d]pyrimidin-4(3H)-one, 6,7-dihydro-3-phenyl-2-(propylthio)-;cortisol,adrenocortical,Phosphodiesterase (PDE),cAMP,BC 11 38,Inhibitor,production,inhibit,levels,cells,BC11-38,BC 1138
- CBNumber
- CB33037165
- Molecular Formula
- C15H16N2OS2
- Formula Weight
- 304.43
- MOL File
- 686770-80-9.mol
More
Less
BC 11-38 Property
- storage temp.
- RT
- solubility
- Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 14 mg/ml with warming).
- form
- solid
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
More
Less
N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 20167
- Product name
- BC-11-38
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $68
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20167
- Product name
- BC-11-38
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20167
- Product name
- BC-11-38
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $252
- Updated
- 2024/03/01
TRC
- Product number
- B129345
- Product name
- BC11-38
- Packaging
- 25mg
- Price
- $285
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7673
- Product name
- BC11-38
- Packaging
- 10mg
- Price
- $291
- Updated
- 2021/12/16
More
Less
BC 11-38 Chemical Properties,Usage,Production
Description
BC-11-38 (686770-80-9) is a? potent and selective inhibitor of phosphodiesterase PDE11 (IC50=0.28 μM).1? IC50s for PDE1-10 are greater than 100 μM. Restores the ability of p54nrb / NONOKD cells to generate cAMP in response to ACTH stimulation and the production of cortisol and DHEA in response to cAMP signaling.2
Uses
BC 11-38 is a selective inhibitor of phosphodiesterase 11. Potent PDE-11 inhibitor
References
1) Ceyhan et al. (2012), Identification of biologically active PDE11-selective inhibitors using a yeast-based high-throughput screen; Chem. Biol., 19 155 2) Lu and Sewer (2015), p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation; Mol. Cell. Biol. 35 1223
BC 11-38 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
BC 11-38 Suppliers
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8449
- Advantage
- 60
- Tel
- +86-400-851-9921
- Fax
- +86-10-82826195
- sales@pharmacodia.com
- Country
- China
- ProdList
- 2317
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9708
- Advantage
- 58
- Tel
- 15076683720
- Fax
- 022-23754520
- klq@cw-bio.com
- Country
- China
- ProdList
- 3500
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131980
- Advantage
- 58
- Tel
- 86-(0)29-85992781 17792393971
- info@lynnchem.com
- Country
- China
- ProdList
- 4587
- Advantage
- 58
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11289
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8141
- Advantage
- 58