(E)-1,4-Dibromobut-2-ene

Product Name: (E)-1,4-Dibromobut-2-ene
CAS No.: 821-06-7
Chemical Name: (E)-1,4-Dibromobut-2-ene
Synonyms: trans-1,4-Dibromo-2-butene;Dibromobutene;4-DibroMo-2-butene;1,4-Dibromo-1-butene;(E)-1,4-Dibromobut-2;1,4-DIBROMO-2-PENTENE;4-dibromo-(e)-2-buten; 1,4-dibromo-, trans-;1,4-Dibromo-2-butene, E;4-dibromo-trans-2-buten
CBNumber: CB3312702
Molecular Formula: C4H6Br2
Formula Weight: 213.9
MOL File: 821-06-7.mol

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(E)-1,4-Dibromobut-2-ene Property

Melting point:: 48-51 °C(lit.)
Boiling point:: 205 °C(lit.)
Density: 1.9393 (estimate)
refractive index: 1.5361 (estimate)
Flash point:: 113°C
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Crystals or Crystalline Powder
color: colorless to slightly brown
Water Solubility: slightly soluble
BRN: 1719696
Stability:: Light Sensitive
InChIKey: RMXLHIUHKIVPAB-OWOJBTEDSA-N
CAS DataBase Reference: 821-06-7(CAS DataBase Reference)
NIST Chemistry Reference: 2-Butene, 1,4-dibromo-, (E)-(821-06-7)
EPA Substance Registry System: 2-Butene, 1,4-dibromo-, (2E)- (821-06-7)

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Safety

Hazard Codes: T,C
Risk Statements: 25-34-23/25
Safety Statements: 26-36/37/39-45-28A
RIDADR: UN 2923 8/PG 2
WGK Germany: 2
RTECS: EM4725000
F: 8-19
Hazard Note: Toxic/Corrosive
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29033990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D39207
Product name: trans-1,4-Dibromo-2-butene
Purity: 99%
Packaging: 25g
Price: $101
Updated: 2025/07/31

Sigma-Aldrich

Product number: D39207
Product name: trans-1,4-Dibromo-2-butene
Purity: 99%
Packaging: 100g
Price: $129
Updated: 2025/07/31

TCI Chemical

Product number: D2944
Product name: trans-1,4-Dibromo-2-butene
Packaging: 25G
Price: $86
Updated: 2025/07/31

TCI Chemical

Product number: D2944
Product name: trans-1,4-Dibromo-2-butene
Packaging: 250G
Price: $644
Updated: 2025/07/31

TRC

Product number: D425545
Product name: (2E)-1,4-Dibromo-2-butene
Packaging: 250g
Price: $410
Updated: 2021/12/16

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(E)-1,4-Dibromobut-2-ene Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(2E)-1,4-Dibromo-2-butene, is used as a reagent in the preparation of diaminoalkenes though copper-mediated diamination reaction.

Synthesis Reference(s)

The Journal of Organic Chemistry, 36, p. 3324, 1971 DOI: 10.1021/jo00821a012

General Description

Crystals or white crystalline solid.

Air & Water Reactions

(E)-1,4-Dibromobut-2-ene may be sensitive to exposure to light and air. Insoluble in water.

Reactivity Profile

(E)-1,4-Dibromobut-2-ene is incompatible with strong oxidizers and strong bases.

Fire Hazard

(E)-1,4-Dibromobut-2-ene is probably combustible.

Synthesis

106-99-0

821-06-7

Example 1 (E)-1,4-dibromo-2-butene (A) Synthesis: 1,3-butadiene (60 mL, 0.70 mol) was added to a 500 mL round-bottomed flask and the flask was placed in a -78 °C cooling bath. Carbon tetrachloride (CCl4, 100 mL) pre-cooled to -20 °C was slowly added to the flask to ensure that the temperature of the reaction mixture was maintained below -20 °C. Subsequently, bromine was added dropwise over a period of 2 hours. The reaction mixture was stirred vigorously at room temperature for 14 hours. After completion of the reaction, most of the solvent was evaporated under reduced pressure. The crude product was purified by recrystallization from cold hexane to afford white crystalline 1,4-dibromo-2-butene (A) (62.4 g, 0.29 mmol) in 58% yield. Thin layer chromatography (TLC) showed an Rf value of 0.74 (unfolding agent ratio hexane:ethyl acetate = 4:1). Nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 300.40 MHz, CDCl3) data were as follows: δ 3.89-4.02 (m, 4H), 5.90-6.05 (m, 2H) ppm.

Purification Methods

Crystallise the dibromide from ligroin and/or distil it in a vacuum. [Beilstein 1 IV 79.]

References

[1] Journal of the American Chemical Society, 2014, vol. 136, # 43, p. 15403 - 15413
[2] Patent: US2008/262271, 2008, A1. Location in patent: Page/Page column 6
[3] Patent: WO2006/38764, 2006, A1. Location in patent: Page/Page column 9-10
[4] Chemische Berichte, 1938, vol. 71, p. 1679
[5] Angewandte Chemie, 1938, vol. 51, p. 919

(E)-1,4-Dibromobut-2-ene Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-dibromo-2,3-butanediol DL-Dithiothreitol

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(E)-1,4-Dibromobut-2-ene Suppliers

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View Lastest Price from (E)-1,4-Dibromobut-2-ene manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: (E)-1,4-Dibromobut-2-ene 821-06-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-10-24

Henan Fengda Chemical Co., Ltd

Product: (E)-1,4-Dibromobut-2-ene 821-06-7
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Weijer International Trade (Hebei) Co., Ltd

Product: (2E)-1,4-Dibromo-2-butene 821-06-7
Price: US $99.00/kg
Min. Order: 1kg
Purity: >99%
Supply Ability: 50000kg/Month
Release date: 2023-03-07

821-06-7, (E)-1,4-Dibromobut-2-eneRelated Search:

CIS-BUTENEDIOIC ANHYDRIDE Maleic acid CIS-2-BUTENE Fumaric acid 1,3-Dibromo-5,5-dimethylhydantoin 1,3-Dibromopropane 2-Butene 3-METHYL-3-BUTEN-1-OL trans,trans-2,4-Undecadienal 1-BUTENE TRAUMATIC ACID TRANS-2-OCTENOIC ACID trans-2-Octenoic acid methyl ester trans-2-Pentenal (+/-)-trans-1,2-Diaminocyclohexane TRANS-1,4-CYCLOHEXANEDIOL trans-1,2-Cyclopentanediol TRANS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID

(2E)-1,4-Dibromo-2-butene

(E)-1,4-Dibromo-2-butene

1,4-Dibromo-2-butene, E

1,4-trans-Dibromobutene-2

2-Butene, 1,4-dibromo-, trans-

4-dibromo-(e)-2-buten

1,4-DIBROMO-2-PENTENE

Trans1butene4-dibroMo -2-

trans-1,4-DibroMo-2-butene 99%

1,4-dibroMo-2-butene (trans)

<i>trans</i>-1,4-Dibromo-2-butene

Tran-1,4-Dibromo-2-Butylene

4-dibromo-trans-2-buten

Dibromobutene

1,4-DIBROMO-2-BUTENE, 99%, PREDOMINANTLY TRANS

1,4-Dibromo-2-Butene,~97%

2-Butene, 1,4-dibromo-, (2E)-

1,4-Dibromo-1-butene

4-dibromo- trans-2-butene

1,4-dibromo-, trans-

(E)-1,4-Dibromobut-2-ene

trans-1,4-Dibromo-2-butene

trans-1,4-DibroMo-2-butene, 97% 100GR

trans-1,4-DibroMo-2-butene, 97% 25GR

1,4-Dibromo-(E)-2-butene

1,4-Dibromo-trans-2-butene

trans-1,4-Dibromo-2-butene,97%

trans-1,4-Dibromo-2-butene ,99%

(E)-1,4-Dibromobut-2

trans-1,4-Dibromo-2-butene ,96%

(2E)-1,4-Dibromobut-2-ene

4-DibroMo-2-butene

trans-1,4-Dibromo-2-butene&gt

trans-1,4-Dibrombut-2-en

(E)-1,4-Dibromobut-2-ene ISO 9001：2015 REACH

(2E)-1,4-Dibromo-2-butene 1

TIANFUCHEM--821-06-7---(E)-1,4-Dibromobut-2-ene

trans-1,4-Dibromo-2-butene, 98%

(E)-1,4-Dibromobut-2-ene - [D90368]

821-06-7

C4H6Br2

BrCH2CHCHCH2Br

medical intermediates

aliskiren

Alkenyl

Halogenated Hydrocarbons

Organic Building Blocks

bc0001

821-06-7