3-BROMO-4-METHOXYANILINE

Product Name: 3-BROMO-4-METHOXYANILINE
CAS No.: 19056-41-8
Chemical Name: 3-BROMO-4-METHOXYANILINE
Synonyms: 4-Amino-2-bromoanisole;3-Bromo-4-methoxyanilin;3-BROMO-4-METHOXYANILINE;3-Bromo-4-methoxyaniline >Benzenamine, 3-bromo-4-methoxy-;4-Amino-2-bromoanisole, 3-Bromo-p-anisidine;3-BROMO-4-METHOXYANILINE ISO 9001：2015 REACH
CBNumber: CB3324820
Molecular Formula: C7H8BrNO
Formula Weight: 202.05
MOL File: 19056-41-8.mol

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3-BROMO-4-METHOXYANILINE Property

Melting point:: 62 °C
Boiling point:: 282.2±20.0 °C(Predicted)
Density: 1.531±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 4.13±0.10(Predicted)
color: White to Brown
InChIKey: NMUFTXMBONJQTC-UHFFFAOYSA-N
CAS DataBase Reference: 19056-41-8

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Safety

Hazard Codes: Xi,N,T+
Risk Statements: 26/27/28-33-50
Safety Statements: 28-36/37-45-61
RIDADR: 2811
HazardClass: IRRITANT
PackingGroup: III
HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3320
Product name: 3-Bromo-4-methoxyaniline
Purity: >96.0%(GC)(T)
Packaging: 1g
Price: $127
Updated: 2025/07/31

TRC

Product number: B683610
Product name: 3-Bromo-4-methoxyaniline
Packaging: 500mg
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 018182
Product name: 3-Bromo-4-methoxyaniline
Purity: 98%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Apolloscientific

Product number: OR45122
Product name: 3-Bromo-4-methoxyaniline
Purity: 97%
Packaging: 1g
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4656-9-Y6
Product name: 3-Bromo-4-methoxyaniline
Purity: 97%
Packaging: 1g
Price: $16
Updated: 2021/12/16

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3-BROMO-4-METHOXYANILINE Chemical Properties,Usage,Production

Uses

3-Bromo-4-methoxyaniline is an intermediate used to prepare triazole analogs of combretastatin A-4 as cytotoxic agents and inhibitors of tubulin. It is also used in the synthesis of (1,2,4-oxadiazolyl)biphenylcarbonyltetrahydrospiro[furo]indolepiperidine (SB-224289) as selective 5-HT1B receptor inverse agonist.

Synthesis

5197-28-4

19056-41-8

General procedure for the synthesis of 3-bromo-4-methoxyaniline from 2-bromo-4-nitroanisole: 2-bromo-4-nitroanisole (0.1 g, 0.43 mmol) was suspended in unstabilized 57% hydriodic acid (1.3 mL), and the reaction was heated for 5 hr at 90 °C. After completion of the reaction, the reaction mixture was cooled, diluted with ethyl acetate (5 mL) and washed sequentially with saturated aqueous sodium thiosulfate and brine. The organic layer was dried over anhydrous magnesium sulfate, filtered and concentrated. The crude product was further purified by silica gel column chromatography to afford 3-bromo-4-methoxyaniline (0.07 g, 80% yield).

References

[1] ACS Catalysis, 2015, vol. 5, # 3, p. 1526 - 1529
[2] Patent: WO2011/98776, 2011, A1. Location in patent: Page/Page column 60
[3] Patent: US2013/53372, 2013, A1. Location in patent: Paragraph 0584; 0585
[4] Patent: US2007/123515, 2007, A1. Location in patent: Page/Page column 24
[5] Justus Liebigs Annalen der Chemie, 1883, vol. 217, p. 44

3-BROMO-4-METHOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-4-METHOXYANILINE Suppliers

Americas 1 China 135 Europe 1 Germany 2 India 10 Japan 1 Sweden 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 4 United States 18 Global 178

GUANGZHOU AANPHARM TECHNOLOGY CO.,LTD

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J & K SCIENTIFIC LTD.

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ShangHai DEMO Chemical Co.,Ltd

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Energy Chemical

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Jia Xing Isenchem Co.,Ltd

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View Lastest Price from 3-BROMO-4-METHOXYANILINE manufacturers

Career Henan Chemical Co

Product: 3-BROMO-4-METHOXYANILINE 19056-41-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-11

19056-41-8, 3-BROMO-4-METHOXYANILINERelated Search:

EOSIN B 2-Bromo-4-nitroanisole EOSIN B 2-BROMO-5-METHOXYANILINE 5-Bromo-2-methoxyaniline, HCl 2-BROMO-4-METHOXYANILINE 2-bromo-5-aminoanisole(4-bromo-3-methoxyaniline),4-BROMO-3-METHOXYANILINE, 98+%,4-Bromo-3-methoxyaniline, 97+%,4-BROMO-3-METHOXYANILINE 4-BROMO-2-METHOXYANILINE[2-AMINO-5-BROMOANISOLE] ,4-BROMO-2-METHOXYANILINE 2-Bromo-5-methoxyaniline, HCl 5-BROMO-2-METHOXYANILINE 2-Bromoanisole 3-BROMO-4-(TRIFLUOROMETHOXY)ANILINE 1,3-DIBROMO-2-METHOXY-5-NITROBENZENE 2-BROMO-1-(4-FLUOROPHENOXY)-4-NITROBENZENE 3-Bromo-4-methoxyaniline hydrochloride 2-BROMO-3-METHOXYANILINE HYDROCHLORIDE 2-BROMO-5-METHOXYANILINE SULPHATE 2-BROMO-6-METHOXYANILINE

3-BROMO-4-METHOXYANILINE

4-Amino-2-bromoanisole

4-Amino-2-bromoanisole, 3-Bromo-p-anisidine

3-Bromo-4-methoxyaniline &gt

Benzenamine, 3-bromo-4-methoxy-

3-BROMO-4-METHOXYANILINE ISO 9001：2015 REACH

3-Bromo-4-methoxyanilin

19056-41-8

Phenyls & Phenyl-Het

Amines

Phenyls & Phenyl-Het