5-BROMO-2-METHOXYANILINE

Product Name: 5-BROMO-2-METHOXYANILINE
CAS No.: 6358-77-6
Chemical Name: 5-BROMO-2-METHOXYANILINE
Synonyms: 5-bromo-o-anisidine;2-amino-4-bromoanisole;4-Bromo-2-aminoanisole;2-Methoxy-5-bromoaniline;5-BROMO-2-METHOXYANILINE;5-Bromo-2-methoxyaniline >5-Bromo-2-methoxyaniline 98%;5-bromo-2-methoxybenzenamine;5-Bromo-2-methoxyaniline, 97%;Benzenamine, 5-bromo-2-methoxy-
CBNumber: CB8454146
Molecular Formula: C7H8BrNO
Formula Weight: 202.05
MOL File: 6358-77-6.mol

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5-BROMO-2-METHOXYANILINE Property

Melting point:: 94-96°C
Boiling point:: 275℃
Density: 1.531
Flash point:: 120℃
storage temp.: 2-8°C
pka: 3.46±0.10(Predicted)
form: powder to crystal
color: Light yellow to Brown
Water Solubility: Slightly soluble in water.
InChI: InChI=1S/C7H8BrNO/c1-10-7-3-2-5(8)4-6(7)9/h2-4H,9H2,1H3
InChIKey: OPGNSNDTPPIYPG-UHFFFAOYSA-N
SMILES: C1(N)=CC(Br)=CC=C1OC
CAS DataBase Reference: 6358-77-6(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 20/21/22-33-43-22
Safety Statements: 26-33-36/37/39-45-36/37
RIDADR: UN2811
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 2921490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 750808
Product name: 5-Bromo-2-methoxyaniline
Purity: 95%
Packaging: 5g
Price: $80.8
Updated: 2025/07/31

TCI Chemical

Product number: B3828
Product name: 5-Bromo-2-methoxyaniline
Purity: >97.0%(T)
Packaging: 1g
Price: $31
Updated: 2025/07/31

TCI Chemical

Product number: B3828
Product name: 5-Bromo-2-methoxyaniline
Purity: >97.0%(T)
Packaging: 5g
Price: $94
Updated: 2025/07/31

Medical Isotopes, Inc.

Product number: 37956
Product name: 5-Bromo-2-methoxyaniline
Purity: 98%
Packaging: 5G
Price: $377
Updated: 2021/12/16

Matrix Scientific

Product number: 009827
Product name: 5-Bromo-2-methoxyaniline
Purity: 98%
Packaging: 100g
Price: $545
Updated: 2021/12/16

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5-BROMO-2-METHOXYANILINE Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

5-Bromo-2-methoxyaniline is used as a pharmaceutical intermediate.

Synthesis

33696-00-3

6358-77-6

General procedure for the synthesis of 5-bromo-2-methoxyaniline from 2-nitro-4-bromoanisole: 1. Preparation of Intermediate 11A: An ethanol (65 mL) solution of 4-bromo-1-methoxy-2-nitrobenzene (2.00 g, 8.62 mmol), zinc powder (5.64 g, 86.0 mmol), and ammonium chloride (4.61 g, 86.0 mmol) was stirred for 2 hours at room temperature. 2. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate (EtOAc) and filtered through diatomaceous earth (CELITE). 3. The filtrate was concentrated by evaporation to give Intermediate 11A (1.74 g, 100% yield) as an off-white solid. 4. Mass spectral analysis (LCMS-ESI) of Intermediate 11A showed m/z 202,204 ([M+H]? , [M+2+H]?) , and a retention time (RT) of 0.70 min (Method J).

References

[1] Patent: WO2014/22343, 2014, A1. Location in patent: Paragraph 00169
[2] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 5, p. 1357 - 1366
[3] Journal fuer Praktische Chemie (Leipzig), 1935, vol. <2> 143, p. 18,24
[4] Gazzetta Chimica Italiana, 1932, vol. 62, p. 51,54
[5] Justus Liebigs Annalen der Chemie, 1883, vol. 217, p. 44

5-BROMO-2-METHOXYANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-METHOXYANILINE Suppliers

Americas 1 China 138 Europe 1 Germany 2 India 14 Japan 1 Sweden 1 Switzerland 1 Ukraine 3 United Kingdom 5 United States 15 Global 182

Shanghai Harvest Chemical Industrial Co., Ltd.

Tel: 021-31038972,31038973 17321035817
Fax: +86-21-51385350
Email: sales@harvest-chem.com
Country: China
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Advantage: 64

J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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Nanjing Chemlin Chemical Co., Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
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Tianjin Jinyuda Chemical Co., Ltd.

Tel: 022-58013646 13011382049
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ProdList: 1930
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View Lastest Price from 5-BROMO-2-METHOXYANILINE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-2-METHOXYANILINE 6358-77-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-BROMO-2-METHOXYANILINE 6358-77-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 5-BROMO-2-METHOXYANILINE 6358-77-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-30

6358-77-6, 5-BROMO-2-METHOXYANILINERelated Search:

4-BROMO-2-NITROANISOLE 4-BROMO-2-FLUORO-6-NITROANISOLE 6-BROMO-2H-1,4-BENZOXAZIN-3(4H)-ONE 5-BROMO-2-BENZOXAZOLINONE 97 LACMOID 2-Bromo-5-methoxyaniline, HCl 4-BROMO-2-METHOXYANILINE[2-AMINO-5-BROMOANISOLE] ,4-BROMO-2-METHOXYANILINE 2-BROMO-4-METHOXYANILINE 4-BROMO-3-METHOXYANILINE, 98+%,2-bromo-5-aminoanisole(4-bromo-3-methoxyaniline),4-Bromo-3-methoxyaniline, 97+%,4-BROMO-3-METHOXYANILINE 5-Bromo-2-methoxyaniline, HCl 2-BROMO-5-METHOXYANILINE 4-Bromoanisole 5,5'-DIBROMO BAPTA AM NS-2028 LABOTEST-BB LT01143471 2-BROMO-4-METHOXYANILINE Hydrochloride 3-Bromo-4-methoxyaniline hydrochloride 2-BROMO-6-METHOXYANILINE

5-BROMO-2-METHOXYANILINE

5-bromo-2-methoxybenzenamine

2-amino-4-bromoanisole

5-bromo-o-anisidine

5-Bromo-2-methoxyaniline 98%

2-Amino-4-bromoanisole, 5-Bromo-o-anisidine

2-Methoxy-5-bromoaniline

4-Bromo-2-aminoanisole

5-Bromo-2-methoxyaniline &gt

Benzenamine, 5-bromo-2-methoxy-

5-Bromo-2-methoxyaniline, 97%

6358-77-6

Amines

blocks

Bromides