1,3-Dimethyl-2-imidazolidinone Property

Melting point:

8.2 °C

Boiling point:

224-226 °C (lit.)

Density 

1.056 g/mL at 25 °C (lit.)

vapor pressure 

<1 hPa (20 °C)

refractive index 

n20/D 1.472(lit.)

Flash point:

220 °F

storage temp. 

Store at +5°C to +30°C.

solubility 

toluene: soluble(lit.)

pka

-0.65±0.20(Predicted)

form 

Liquid

color 

Clear

explosive limit

1.3-8.4%(V)

Water Solubility 

freely soluble

Sensitive 

Hygroscopic

Merck 

14,3249

BRN 

108808

InChIKey

CYSGHNMQYZDMIA-UHFFFAOYSA-N

LogP

-0.3 at 25℃

CAS DataBase Reference

80-73-9(CAS DataBase Reference)

NIST Chemistry Reference

1,3-Dimethyl-2-imidazolidinone(80-73-9)

EPA Substance Registry System

N,N'-Dimethylimidazolidinone (80-73-9)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

21/22-38-41-36/38-62-22

Safety Statements 

26-36-36/37/39-36/37

RIDADR 

UN 2810 6.1/PG 3

WGK Germany 

3

RTECS 

NJ0660000

F 

3

Autoignition Temperature

305 °C

Hazard Note 

Harmful/Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

Ⅲ

HS Code 

29332990

Toxicity

LD50 orally in Rabbit: 1261 mg/kg LD50 dermal Rabbit 986 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

1,3-Dimethyl-2-imidazolidinone Chemical Properties,Usage,Production

Description

DMI, a high purity aprotic solvent, is composed of nitrogen containing five membered ring compound and widely recognized as an epoch making solvent. It is a colorless, transparent, high polar solvent with high thermal and chemical stability and non-corrosiveness. The material has a high boiling point of 222° C, a high flash point of 120° C (open method) / 95° C (close method), and a low melting point of 7.5° C.

Chemical Properties

Almost colorless, clear liquid

Uses

1,3-Dimethyl-2-imidazolidinone is used as a high-boiling polar aprotic solvent. It is used as a substitute solvent for toxic hexamethylphosphoramide. It finds application in detergents, dyestuffs, electronic materials and in the manufacture of polymers. It is involved in the preparation of 1,2-bis(trimethylsilyl)benzene. Further, it is utilized as a solvent during alfa-regioselective prenylation of imines. In addition to this, it constitutes the mobile phase during size-exclusion chromatographic analysis of cellulose.

Uses

DMI can be used in a variety of applications including detergents, dyestuffs, electronic materials and in the manufacture of polymers. Its versatility can be attributed to it. Of particular note are its excellent solubility for inorganic and organic compounds and high dielectric constant and solvation effect.

Uses

1,3-Dimethyl-2-imidazolidinone may be used:

• As substitute solvent for hexamethylphosphoric triamide (HMPA) in the synthesis of 1,2-bis(trimethylsilyl)benzene.
• As solvent during the α-regioselective prenylation of imine.
• As component of mobile phase for the size-exclusion chromatographic analysis of cellulose.

Definition

ChEBI: 1,3-Dimethyl-2-imidazolidinon is an imidazolidinone.

General Description

1,3-Dimethyl-2-imidazolidinone (DMI) is an imidazolidine derivative. It is reported to act as a promoter by minimizing the formation of dialkylation byproducts and accelerating the rate of monoalkylation of γ-butyrolactone. Conversion of CO₂ to form lower alcohols by homogeneous catalytic hydrogenation using DMI as solvent has been investigated.

Flammability and Explosibility

Non flammable