Methyl 4-oxotetrahydrothiophene-3-carboxylate

ChemicalBook > CAS DataBase List > Methyl 4-oxotetrahydrothiophene-3-carboxylate

Methyl 4-oxotetrahydrothiophene-3-carboxylate

Product Name: Methyl 4-oxotetrahydrothiophene-3-carboxylate
CAS No.: 2689-68-1
Chemical Name: Methyl 4-oxotetrahydrothiophene-3-carboxylate
Synonyms: AKOS 92615;methyl tetrahydro-4-oxo-3-thenoate;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE;3-Carbomethoxytetrahydrothiophene-4-one;METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE;METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE;Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97%;Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+%;tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester
CBNumber: CB3354748
Molecular Formula: C6H8O3S
Formula Weight: 160.19
MOL File: 2689-68-1.mol

Less

Methyl 4-oxotetrahydrothiophene-3-carboxylate Property

Melting point:: 37-38 °C
Boiling point:: 95 °C
Density: 1.309±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Chloroform
form: Solid
pka: 10.52±0.20(Predicted)
color: Light Yellow
InChI: InChI=1S/C6H8O3S/c1-9-6(8)4-2-10-3-5(4)7/h4H,2-3H2,1H3
InChIKey: LEAKUJFYXNILRB-UHFFFAOYSA-N
SMILES: C1SCC(=O)C1C(OC)=O
EPA Substance Registry System: 3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester (2689-68-1)

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
HazardClass: IRRITANT
HS Code: 29339900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

TRC

Product number: T294170
Product name: Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster
Packaging: 5G
Price: $440
Updated: 2021/12/16

TRC

Product number: T294170
Product name: Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster
Packaging: 25g
Price: $1650
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0030710
Product name: METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 10G
Price: $1320.38
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0030710
Product name: METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $631.34
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 67223
Product name: Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster
Packaging: 500mg
Price: $650
Updated: 2021/12/16

Less

Methyl 4-oxotetrahydrothiophene-3-carboxylate Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

Methyl 4-oxotetrahydrothiophene-3-carboxylate is used in the preparation of a new class of neuroleptic agents.

Synthesis

2,3,4,5-Tetrahydro-4-oxo-3-thiophene carboxylic acid, methyl ester (L75a): 25.3 g (1.1 mol) of sodium were implemented in 190 mL abs. methanol to methylate. To methylate solution 70 g (0.360 mol) (L74) was added dropwise at the boiling point and the reaction mixture was heated for 45 min under reflux. The cooling mixture was poured onto a mixture of 500 mL ice and 300 mL water, acidified with 100 mL conc. HCl and the oily precipitating product was brought to crystallize under cooling with ice/sodium chloride bath. The crystals were sucked off, resumed in 100 mL methylene chloride and dried over sodium sulfate and evaporated. There were obtained 16.7 g of pale beige crystals. The aqueous phase was extracted three times with 100 mL of methylene chloride, the organic phase dried over sodium sulfate and evaporated. 30 g of crystalline product Methyl 4-oxotetrahydrothiophene-3-carboxylate was obtained. Yield: 46.7 g of light beige crystals (81 % of theory). mp 29-31 degC. TLC: Bz:MeOH:AcOH = 45:8:4, Rf = 0.75.

Methyl 4-oxotetrahydrothiophene-3-carboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Toluene Sodium Methoxide Methyl acrylate

Preparation Products

Less

Methyl 4-oxotetrahydrothiophene-3-carboxylate Suppliers

Belgium 1 Canada 1 China 97 Europe 1 Germany 5 India 3 Switzerland 1 United Kingdom 8 United States 17 Global 134

Shandong Youfu Pharmaceutical Technology Co., Ltd.

Tel: +86-0536-8226195 +86-13953676784
Email: lee@unipharm-sd.com
Country: China
ProdList: 509
Advantage: 58

BioPharmaMatrix,Inc.

Tel: 0510-86010668
Fax: 0510-86010668
Email: sales@biopharmamatrix.com
Country: China
ProdList: 4110
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11655
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Heterochem

Tel: 027-88041443 13072715837
Fax: 027-51829379
Email: sales@hetero-chem.com
Country: China
ProdList: 696
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Tianjin Yao Technology Development Co., Ltd.

Tel: 022-18902014291 18902014291
Fax: 022-66211080
Email: byswxsb01@163.com
Country: China
ProdList: 98
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8878
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 18017383231 18017383231
Fax: qq：2817624287
Email: lyh_antaeus@163.com
Country: China
ProdList: 9347
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9648
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11481
Advantage: 59

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q3252066219
Fax: QQ3382968513
Email: danping@shsendpharm.com
Country: China
ProdList: 3130
Advantage: 55

ShangHai Siyan Biological Technology Co., Ltd.

Tel: 021-50908862，442785678，326799392 18721037013
Fax: 021-50908862
Email: siyansales@126.com
Country: China
ProdList: 9627
Advantage: 58

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9942
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28810
Advantage: 58

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718 +86-13336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29791
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Xi 'an billiton biological technology co., LTD

Tel: 18191268030
Fax: 029 88764766
Email: wang.yali@xatuochao.com
Country: China
ProdList: 116
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52693
Advantage: 58

Xi'an Yutebang New Material Technology Co., Ltd.

Tel: 029-84536388 18717328141
Fax: 029-84536389
Email: ella@yutbon.com
Country: China
ProdList: 191
Advantage: 58

Suzhou Vosun Biotech Co.,Ltd

Tel: 0512-66569378-8002 66569378
Fax: 0512-82177265
Email: info@vosunchemical.com
Country: China
ProdList: 721
Advantage: 58

Finetech Industry Limited

Tel: +86-27-87465837 +8618971612321
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9639
Advantage: 58

Unipharm pharmaceutical industry Co., Ltd

Tel: 536-8266195 +8613953676784
Email: lee@unipharm-sd.com
Country: China
ProdList: 1202
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22883
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34553
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9911
Advantage: 58

SIMAGCHEM CORP

Tel: +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17365
Advantage: 58

Suzhou XiBoli Biotechnology Co., Ltd.

Tel: 17326194005
Email: 1873444526@qq.com
Country: China
ProdList: 495
Advantage: 58

Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7118
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49374
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29811
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Neostar United (Changzhou) Industrial Co., Ltd.

Tel: +86-0519-85551759 +8613506123987
Fax: +0086-519-85557389
Email: marketing1@neostarunited.com
Country: China
ProdList: 8838
Advantage: 58

Xi'an Yutbon Phamaceutial Technology Co., Ltd.

Tel: 029-84536388 18717328141
Fax: 029-84536389
Email: sales@yutbon.com
Country: China
ProdList: 150
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

LEWOO PHARMATECH (SHANGHAI) CO.,LTD

Tel: 15800805830
Fax: 021 67898603
Email: miao@lewoopharma.com.cn
Country: China
ProdList: 695
Advantage: 58

Mainchem Co., Ltd.

Tel: --
Fax: --
Email: sarah@mainchem.com
Country: China
ProdList: 6567
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44458
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 31121
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

Less

View Lastest Price from Methyl 4-oxotetrahydrothiophene-3-carboxylate manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Methyl 4-oxotetrahydrothiophene-3-carboxylate 2689-68-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-22

Career Henan Chemical Co

Product: METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 2689-68-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 85.0-99.8%
Supply Ability: 20ton
Release date: 2019-12-20

2689-68-1, Methyl 4-oxotetrahydrothiophene-3-carboxylate Related Search:

HYDROXYECTOINE TERT-BUTYL 4-OXOCYCLOHEXANECARBOXYLATE Tetrahydrothiophene METHYL 3-OXOTETRAHYDROTHIOPHENE-2-CARBOXYLATE Methyl 4-oxotetrahydrothiophene-3-carboxylate 3-MERCAPTOISOBUTYRIC ACID 4-OXOTETRAHYDROTHIOPHENE-2,3-DICARBOXYLIC ACID DIMETHYL ESTER Tetrahydrothiophen-3-one 4-Mercapto-2-butanone 2-METHYL-1-BUTANETHIOL 1-(Methylthio)-2-butanone 4-METHYLTETRAHYDROTHIOPHEN-3-ONE 3-Methylthiolane METHYL 4-(METHYLTHIO)BUTYRATE

4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE

AKOS 92615

tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester

METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE

methyl tetrahydro-4-oxo-3-thenoate

4-Oxo-Tetrahydro-Thiophene-3-CarboxylicAcidMethylEster

4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE

Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+%

METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE

Tetrahydro-4-oxo-3-thiophenecarboxylic acid methyl ester

Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97%

Methyl 4-oxotetrahydrothiophene-3-carboxylate , Tech.

3-(Methoxycarbonyl)-4-oxotetrahydrothiophene, 3-(Methoxycarbonyl)-4-oxothiolane

Methyl 4-oxotetrahydrothiophene-3-carboxylate, technical

METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH

4-Oxytetrahydrophenol-3-carboxylic acid methyl ester

3-Carbomethoxytetrahydrothiophene-4-one

2689-68-1

KETONE

Esters

Thiophenes & Benzothiophenes