ChemicalBook > CAS DataBase List > 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate

2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate

Product Name
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
CAS No.
125700-67-6
Chemical Name
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate
Synonyms
TBTU;2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE;TBPIPU;TBTU N;TBTU, 98%;TBTU 99.5%;KNORR REAGENT;TBTU extrapure;TBTU [ 125700-67-6;TBTU (Knorr reagent)
CBNumber
CB3357547
Molecular Formula
C11H16BF4N5O
Formula Weight
321.09
MOL File
125700-67-6.mol
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2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate Property

Melting point:
205 °C (dec.)(lit.)
storage temp. 
2-8°C
solubility 
acetonitrile: 0.1 g/mL, clear
form 
Powder
color 
White to Almost white
Water Solubility 
Soluble in acetonitrile (100 mg/ml, clear, colorless), DMF (160.55 mg/ml, clear), and water (3 mg/ml at 20°C).
Sensitive 
Moisture Sensitive
BRN 
7066325
InChIKey
NQGZJNPFMLJDKU-UHFFFAOYSA-M
LogP
-2.65 at 21℃
CAS DataBase Reference
125700-67-6(CAS DataBase Reference)
EPA Substance Registry System
1H-Benzotriazolium, 1-[bis(dimethylamino)methylene]-, 3-oxide, tetrafluoroborate(1-) (1:1) (125700-67-6)
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Safety

Hazard Codes 
Xi,F,E
Risk Statements 
36/37/38-5-2
Safety Statements 
26-36-37/39-36/37/39-35
RIDADR 
1325
WGK Germany 
3
F 
8-10-21
Hazard Note 
Irritant/Flammable
HS Code 
2933 99 80
HazardClass 
4.1
PackingGroup 
Ⅱ
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
12806
Product name
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity
≥97.0% (N)
Packaging
5G
Price
$68.2
Updated
2024/03/01
Sigma-Aldrich
Product number
12806
Product name
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity
≥97.0% (N)
Packaging
25g
Price
$187
Updated
2024/03/01
Sigma-Aldrich
Product number
12806
Product name
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity
≥97.0% (N)
Packaging
100g
Price
$501
Updated
2024/03/01
Sigma-Aldrich
Product number
12806
Product name
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity
≥97.0% (N)
Packaging
250g
Price
$1000
Updated
2023/06/20
Sigma-Aldrich
Product number
12806
Product name
O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate
Purity
≥97.0% (N)
Packaging
1KG
Price
$3430
Updated
2022/05/15
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2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate Chemical Properties,Usage,Production

Chemical Properties

2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate is WHITE TO PALE CREAM FINE CRYSTALLINE POWDER

Uses

Coupling reagent for peptide synthesis causing low racemization. R. Knorr, A. Trzeciak, W. Bannwarth and D. Gillessen, THL 30, 1927 (1989)

Uses

Coupling reagent which is ideally suited for solid-phase peptide synthesis.

Uses

2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate is used in the synthesis of tetrapeptoid analogues of the antiprotocoal compound Apicidin (A726300). Also used in the synthesis of acid based t-antigen glycodendrimers.

reaction suitability

reaction type: Coupling Reactions

2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate Preparation Products And Raw materials

Raw materials

Preparation Products

1-(PIPERIDIN-4-YLCARBONYL)PIPERIDINE
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2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate Suppliers

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View Lastest Price from 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate 125700-67-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-10
Jinan Finer Chemical Co., Ltd
Product
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate 125700-67-6
Price
US $12.00-11.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200mt
Release date
2022-09-13
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate 125700-67-6
Price
US $500.00-300.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-23

125700-67-6, 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborateRelated Search:

Tolyltriazole AZURE B TETRAFLUOROBORATE 1,1,3,3-Tetramethylurea 1H-Benzotriazole 5-Methyl-1H-benzotriazole Ribavirin 1,2,3-1H-Triazole O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride 3-Hydroxy-1,2,3-benzotriazin-4(3H)-one 2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate HOAt 1-Hydroxybenzotriazole HBTU HATU Fluoroboric acid 1-Hydroxybenzotriazole hydrate 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate

  • benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate
  • [benzotriazol-1-yloxy(dimethylamino)methylene]-dimethyl-ammonium
  • 1-[Bis(dimethylamino)methylene]-1H-benzotriazolium 3-Oxide Tetrafluoroborate
  • O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-(1H-BENZOTRIAZOLE-1-YL) N,N,N',N'-TETRAMETHYL URONIUM TETRAFLUOROBORATE
  • O-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYL-URONIUM TETRAFLUOROBORATE
  • O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-PENTAMETHYLENE-URONIUM TETRAFLUOROBORATE
  • O-(1H-BENZO-1,2,3-TRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYL-URONIUM TETRAFLUOROBORATE
  • O-(BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • N-[(1H-BENZOTRIAZOL-1-YL)(DIMETHYL-AMINO)METHYLENE]-N-METHYL-METHANAMINIUM TETRAFLUOROBORATE
  • TBPIPU
  • TBTU
  • TETRAFLUOROBORATE TBTU
  • O-BENZOTRIAZOL-1-YL-N,N,N',N'-TETRA- &
  • O-BENZOTRIAZOL-1-YL-N,N,N',N'-TETRAMETHY LURONIUM
  • TBTU,O-(BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-Benzotriazol-lYL-N,N',N'-Tetramethyluronium Tetrafluoroborate
  • 2-(1H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE (TBTU)
  • O-Benzotriazol-1-yl-N,N,N',N'-tetramethylisouronium tetrafluoroborate
  • TBTU/2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumtetrafluoroborate
  • O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluro
  • 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetraMethyluroni
  • 1H-BenzotriazoliuM-1-[bis(diMethylaMine)
  • 2-(1H-Benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetraMethyluroniuM tetrafluoroborate
  • TBTU, [(1H-Benzotriazol-1-yl)oxy](dimethylamino)-N,N-dimethylmethaniminium tetrafluoroborate
  • O-(BENZOTRIAZOLE-1-YL)-N,N,N',N'-TETRAMETHYL URONIUM TETRAFLUORO BORATE
  • KNORR REAGENT
  • 2-(1H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • 2-(1H-BENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM TETRAFLUOROBORATE
  • O-(Benzotriazol-1-yl)-N,N,N',N'-tetraMethyluroniuM tetrafluoroborate >=97.0% (N)
  • 3-[(dimethylamino)(dimethyliminiumyl)methyl]-1-oxo-2,3-dihydro-1H-1λ?,2,3-benzotriazol-1-ylium-2-ide
  • 2-(1H-Benzotriazole-1-yl)-1,1,3,3-Tetram
  • TBTU (Knorr reagent)
  • O-(1H-BENZOTRIAZOL-1-YL)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE(TBTU)
  • O-Benzotriazol-l-yl- N,N,N'',N'',- tetramethyluroniumtetrafluoroborate
  • O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium Tetrafluoroborate (TBTU)
  • TDBTU (O-(3,4-DIHYDRO-4-OXO-1,2,3-BENZOTRIAZIN-3-YL)-N,N,N'',N''-TETRAMETHYLURONIUM TETRAFLUOROBORATE)
  • N-[(1H-Benzotriazol-1-yl)(dimethylamino)methylene]-N-methylmethanaminium tetrafluoroborate N-oxide
  • O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate [Coupling Reagent for Peptide]
  • TBTU extrapure
  • benzotriazolyl tetramethyluronium fluoroborate
  • 2-(1H-Benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate, 97+%
  • TBTU (o-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluo
  • benzotriazol-1-yl-N-tetramethyl-uronium tetrafluoroborate
  • O-Benzotriazol-1-yl-N,N,N',N'-tetramethyluronium tetrafluoroborate,97%
  • O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetraMethyluroniuM tetrafluoroborate, 99%, 99%
  • TBTU 99.5%
  • O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate≥ 98% (HPLC)
  • N,N,N′,N′-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate
  • TBTU 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate Novabiochem
  • O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate for synthesis
  • (Benzotriazol-1-yloxy-dimethylamino-methylene)dimethylammonium tetrafluoroborate
  • [dimethylamino-(3-oxidobenzotriazol-3-ium-1-yl)methylidene]-dimethylazanium
  • TBTU [Coupling Reagent for Peptide]
  • O-(1H-BENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM TETRAFL
  • TBTU, N,N,Nμ,Nμ-Tetramethyl-O-(benzotriazol-1-yl)uronium tetrafluoroborate
  • O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate [Coupling Reagent for Peptide]&gt
  • TBTU N