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5-Bromo-2-fluorobenzaldehyde

Product Name
5-Bromo-2-fluorobenzaldehyde
CAS No.
93777-26-5
Chemical Name
5-Bromo-2-fluorobenzaldehyde
Synonyms
3-BroMo-6-fluorobenzaldehyde;2-FLUORO-5-BROMOBENZALDEHYDE;AKOS BBS-00003261;LABOTEST-BB LT01143303;5-Bromo-2-fluorobenzaldehyd;5-BROMO-2-FLUOROBENZALDEHYDE;Benzaldehyde, 5-bromo-2-fluoro-;5-Bromo-2-fluorobenzaldehyde98%;5-Bromo-2-fluorobenzaldehyde 98%;5-Bromo-2-fluorobenzaldehyde >
CBNumber
CB3364493
Molecular Formula
C7H4BrFO
Formula Weight
203.01
MOL File
93777-26-5.mol
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5-Bromo-2-fluorobenzaldehyde Property

Melting point:
58-62°C
Boiling point:
230 °C (lit.)
Density 
1.71 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.57(lit.)
Flash point:
229 °F
storage temp. 
2-8°C
form 
powder to lump to clear liquid
Specific Gravity
1.710
color 
White or Colorless to Light yellow
Water Solubility 
INSOLUBLE
Sensitive 
Air Sensitive
BRN 
7632798
InChI
InChI=1S/C7H4BrFO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H
InChIKey
MMFGGDVQLQQQRX-UHFFFAOYSA-N
SMILES
C(=O)C1=CC(Br)=CC=C1F
CAS DataBase Reference
93777-26-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29130000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
528870
Product name
5-Bromo-2-fluorobenzaldehyde
Purity
97%
Packaging
25g
Price
$105
Updated
2025/07/31
TCI Chemical
Product number
B1789
Product name
5-Bromo-2-fluorobenzaldehyde
Purity
>95.0%(GC)
Packaging
5g
Price
$22
Updated
2025/07/31
TCI Chemical
Product number
B1789
Product name
5-Bromo-2-fluorobenzaldehyde
Purity
>95.0%(GC)
Packaging
25g
Price
$87
Updated
2025/07/31
TRC
Product number
B684525
Product name
5-Bromo-2-fluorobenzaldehyde
Packaging
500g
Price
$1230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0024448
Product name
5-BROMO-2-FLUOROBENZALDEHYDE
Purity
95.00%
Packaging
50G
Price
$2471.7
Updated
2021/12/16
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5-Bromo-2-fluorobenzaldehyde Chemical Properties,Usage,Production

Chemical Properties

clear yellowish liquid after melting

Uses

5-Bromo-2-fluorobenzaldehyde is used for the preparation of benzimidazole derivatives as inhibitors of leukotriene production.

Synthesis

446-52-6

93777-26-5

Example 3: In a reactor equipped with an electric stirrer, a thermometer, a dropping funnel and a condenser tube, 500 mL of aqueous sulfuric acid solution was added. Subsequently, a mixture of 167 g (1 mol) of potassium bromate and 124.1 g (1 mol) of 2-fluorobenzaldehyde was slowly added dropwise to the reaction system, the reaction temperature was maintained at 90°C, and the dropwise process continued for 2 to 3 hours. Upon completion of the reaction, 1000 mL of water was added to the system and extracted using methyl tert-butyl ether. The organic phase was subsequently washed with aqueous sodium sulfite and dried over anhydrous sodium sulfate. The dried organic phase was filtered and concentrated to remove the methyl tert-butyl ether to give a brownish red oil. Finally, the 63-65°C/3 mmHg fraction was collected by vacuum distillation to afford 178 g of the target product 5-bromo-2-fluorobenzaldehyde in 88% yield and 97% purity.

References

[1] Patent: CN105884591, 2016, A. Location in patent: Paragraph 0008; 0009; 0010; 0011

5-Bromo-2-fluorobenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-2-fluorobenzaldehyde Suppliers

TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
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View Lastest Price from 5-Bromo-2-fluorobenzaldehyde manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
5-Bromo-2-fluorobenzaldehyde 93777-26-5
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-29
Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-Bromo-2-fluorobenzaldehyde 93777-26-5
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-10
Suzhou Nordica Biopharma CO.,LTD
Product
5-bromo-2-fluorobenzaldehyde 93777-26-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2024-11-15

93777-26-5, 5-Bromo-2-fluorobenzaldehydeRelated Search:


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