1-Bromo-4-nitrobenzene Property

Melting point:

124-126 °C(lit.)

Boiling point:

255-256 °C(lit.)

Density 

1,95 g/cm³

refractive index 

1.6060 (estimate)

Flash point:

254-256°C

storage temp. 

Store below +30°C.

solubility 

soluble in Chloroform

form 

Crystalline Powder

color 

Light yellow

Water Solubility 

insoluble

BRN 

636964

InChIKey

ZDFBKZUDCQQKAC-UHFFFAOYSA-N

CAS DataBase Reference

586-78-7(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 1-bromo-4-nitro-(586-78-7)

EPA Substance Registry System

Benzene, 1-bromo-4-nitro- (586-78-7)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-20/21/22-62-51/53-46-45

Safety Statements 

36/37/39-26-22-61-53-45

RIDADR 

UN 3459 6.1/PG 3

WGK Germany 

3

RTECS 

CY9040550

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29049085

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

1-Bromo-4-nitrobenzene Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

It can be employed as a syntheses material intermediate. It is also used as a pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron, 43, p. 4321, 1987 DOI: 10.1016/S0040-4020(01)90307-2

Purification Methods

Crystallise it twice from pet ether, using charcoal before the first crystallisation. [Beilstein 5 III 619, 5 IV 729.]