Caulophylline
- Product Name
- Caulophylline
- CAS No.
- 486-86-2
- Chemical Name
- Caulophylline
- Synonyms
- (1r)-l;Caulophyllin;Caulophylline;Methylcytisine;N-METHYLCYTISINE;12-Methylcytisine;12-methyl-cytisin;Cytisine, 12-methyl-;METHYLCYTISINE, N-(P);Caulophylline USP/EP/BP
- CBNumber
- CB3366194
- Molecular Formula
- C12H16N2O
- Formula Weight
- 204.27
- MOL File
- 486-86-2.mol
Caulophylline Property
- Melting point:
- 137-139oC
- alpha
- 30D -224° (c = 1.05 in water)
- Boiling point:
- 342.77°C (rough estimate)
- Density
- 1.0565 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- powder
- pka
- 9.61±0.20(Predicted)
- color
- White to Off-White
- NIST Chemistry Reference
- Caulophylline(486-86-2)
N-Bromosuccinimide Price
- Product number
- SMB00353
- Product name
- N-Methylcytisine
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $197
- Updated
- 2024/03/01
- Product number
- PHL83219
- Product name
- N-Methylcytisine
- Purity
- phyproof? Reference Substance
- Packaging
- 10mg
- Price
- $574
- Updated
- 2024/03/01
- Product number
- CDS010442
- Product name
- N-Methylcytisine
- Purity
- AldrichCPR
- Packaging
- 25mg
- Price
- $308
- Updated
- 2023/06/20
- Product number
- M3398-60
- Product name
- N-Methylcytisine
- Packaging
- 25mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- M294680
- Product name
- N-Methylcytisine
- Packaging
- 100mg
- Price
- $460
- Updated
- 2021/12/16
Caulophylline Chemical Properties,Usage,Production
Description
This base was first prepared synthetically by Partheil and subsequently discovered in the roots of Caulophyllurn thalictroides L. It is widespread among the Papilionaceae, being found in Baptisia australis, Genista tinctoria, Sophora microphylla, S. tetraptera, Thermopsis lanceolata and T. rhombifolia (Watt.) Richards. It is laevorotatory with [α]20D - 221 ° (H20) and furnishes the following crystalline salts and derivatives: hydrochloride, m.p. 2S0-SoC (dec.); hydriodide, m.p. 246-7°C (dec.); perchlorate, m.p. 2S4°C (dec.); aurichloride, m.p. 206°C (dec.); picrate, m.p. 230°C; picrolonate, m.p. 224-SoC (dec.) and the methiodide which occurs in two modifications, m.p. 248°C and 267-276°C.
Chemical Properties
Colourless Needles
Uses
N-Methylcytisine (cas# 486-86-2) is a compound useful in organic synthesis.
General Description
N-Methylcytisine is a nicotinic alkaloid found in Caulophyllum thalictroides, also known as blue cohosh.
Hazard
Extremely toxic; cardiotoxic; poisonous.
Biochem/physiol Actions
N-Methylcytisine is toxic and binds selectively to nicotinic acetylcholine receptors in the CNS.
References
Partheil., Arch. Pharm., 230,448 (1892)
Power, Salway., J. Chem. Soc., 103, 194 (1913)
Caulophylline Preparation Products And Raw materials
Raw materials
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View Lastest Price from Caulophylline manufacturers
- Product
- N-Methylcytisine 486-86-2
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-11
- Product
- Caulophylline 486-86-2
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2018-12-24