ChemicalBook > CAS DataBase List > 1-METHANESULFONYL-PIPERAZINE

1-METHANESULFONYL-PIPERAZINE

Product Name
1-METHANESULFONYL-PIPERAZINE
CAS No.
55276-43-2
Chemical Name
1-METHANESULFONYL-PIPERAZINE
Synonyms
AKOS B003961;1-mesylpiperazine;CHEMBRDG-BB 3003961;ART-CHEM-BB B003961;ART-CHEM-BB B022241;IFLAB-BB F2124-0764;TIMTEC-BB SBB007001;1-METHYLSULPHONYLPIPERAZINE;1-METHANESULFONYL-PIPERAZINE;1-(METHYLSULFONYL)PIPERAZINE
CBNumber
CB3368178
Molecular Formula
C5H12N2O2S
Formula Weight
164.23
MOL File
55276-43-2.mol
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1-METHANESULFONYL-PIPERAZINE Property

Melting point:
99 °C
Boiling point:
280.6±50.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
7.78±0.10(Predicted)
form 
Solid
color 
White to Almost white
Water Solubility 
Slightly soluble in water.
CAS DataBase Reference
55276-43-2(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36/37/39-24/25-23
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2437
Product name
1-(Methylsulfonyl)piperazine
Purity
>98.0%(GC)
Packaging
5g
Price
$80
Updated
2025/07/31
TRC
Product number
B486145
Product name
1-(Methylsulfonyl)piperazine
Packaging
100mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR0841
Product name
1-(Methylsulphonyl)piperazine
Purity
98+%
Packaging
5g
Price
$80
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK192210
Product name
1-Methanesulfonyl-piperazine
Purity
98%
Packaging
1g
Price
$80
Updated
2021/12/16
Matrix Scientific
Product number
028784
Product name
1-(Methylsulfonyl)piperazine
Packaging
25g
Price
$114
Updated
2021/12/16
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1-METHANESULFONYL-PIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

1-(Methylsulfonyl)piperazine is employed as a intermediate for pharmaceutical and chemical research.

Synthesis

164331-38-8

55276-43-2

Step 2: Synthesis of 1-(methylsulfonyl)piperazine A mixture of tert-butyl 4-(methylsulfonyl)piperazine-1-carboxylate (1.0 g, 3.79 mmol) with trifluoroacetic acid (TFA, 0.86 g, 7.58 mmol) in dichloromethane (CH2Cl2, 10 mL) was stirred for 2 hours at room temperature. After completion of the reaction, the mixture was concentrated under reduced pressure to afford 1-(methylsulfonyl)piperazine as a yellow oil (0.5 g, 80.52% yield). The product was characterized by 1H NMR (400 MHz, CD3OD): δ 3.50-3.47 (m, 4H), 3.33-3.28 (m, 4H), 2.92 (s, 3H); ESI-MS m/z: 165 ([M + H]+).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 1, p. 375 - 379
[2] Patent: WO2010/141538, 2010, A1. Location in patent: Page/Page column 23
[3] Patent: WO2004/43950, 2004, A1. Location in patent: Page 152
[4] Patent: WO2005/51957, 2005, A1. Location in patent: Page/Page column 61-62
[5] Patent: WO2004/85425, 2004, A1. Location in patent: Page 98

1-METHANESULFONYL-PIPERAZINE Preparation Products And Raw materials

Raw materials

Di-tert-butyl dicarbonate Trifluoroacetic acid Triethylamine Chloroform Piperazine Ethyl chloroformate Methanesulfonyl chloride Isopropyl acetate Diethyl ether Ethyl acetate Dichloromethane Methanol Sodium hydroxide Isopropyl alcohol Sodium carbonate

Preparation Products

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1-METHANESULFONYL-PIPERAZINE Suppliers

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View Lastest Price from 1-METHANESULFONYL-PIPERAZINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-METHANESULFONYL-PIPERAZINE 55276-43-2
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-27
Hebei Zhanyao Biotechnology Co. Ltd
Product
1-METHANESULFONYL-PIPERAZINE 55276-43-2
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-04
Hebei Zhanyao Biotechnology Co. Ltd
Product
1-METHANESULFONYL-PIPERAZINE 55276-43-2
Price
US $10.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2021-11-05

55276-43-2, 1-METHANESULFONYL-PIPERAZINERelated Search:

1-(5-ISOQUINOLINESULFONYL)PIPERAZINE, DIHYDROCHLORIDE H-7 DIHYDROCHLORIDE 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE 1-(8-CHLORO-5-ISOQUINOLINE-SULFONYL)PIPERAZINE 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE DIHYDROCHLORIDE 1-(5-ISOQUINOLINYLSULFONYL)-3-METHYL-PIPERAZINE 1-METHANESULFONYL-PIPERAZINE HYDROCHLORIDE 1-(Methanesulfonyl)-piperazine / 1-(Methanesulfonyl)-piperazine monohydrochloride N,N'-BIS(P-TOLUENESULFONYL)PIPERAZINE 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-((1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRROL-2-YL)SULFONYL)PIPERAZINE 7-(4-[(4-CHLOROPHENYL)SULFONYL]PIPERAZINO)-2,4-BIS(TRIFLUOROMETHYL)[1,8]NAPHTHYRIDINE 2-NITRO-1-((4-(5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)BENZENE 1-((4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)-2-NITROBENZENE ETHYL 2-(1-[(4-CHLOROPHENYL)SULFONYL]-3-OXO-2-PIPERAZINYL)ACETATE 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4-[(4-METHYLPHENYL)SULFONYL]PIPERAZINE N,1-DIMETHYL-6-[4-(METHYLSULFONYL)PIPERAZINO]-3,5-DINITRO-1,4-DIHYDRO-2-PYRIDINAMINE N,N'-BIS(BENZENESULFONYL)PIPERAZINE N,N'-BIS(O-TOLUENESULFONYL)PIPERAZINE

  • 1-METHANESULFONYL-PIPERAZINE
  • 1-N-METHANESULFONYLPIPERAZINE
  • 1-(METHYLSULFONYL)PIPERAZINE
  • 1-METHYLSULPHONYLPIPERAZINE
  • AKOS B003961
  • CHEMBRDG-BB 3003961
  • 1-METHANESULFONYL-PIPERAZINE >98%
  • 1-(Methylsulphonyl)piperazine 98+%
  • IFLAB-BB F2124-0764
  • ART-CHEM-BB B022241
  • ART-CHEM-BB B003961
  • TIMTEC-BB SBB007001
  • 1-(methylsulfonyl)piperazine(SALTDATA: FREE)
  • Methyl (piperazin-1-yl) sulphone
  • Piperazine, 1-(methylsulfonyl)-
  • 1-mesylpiperazine
  • 1-(Methylsulfonyl)piperazine&gt
  • 1-(Methylsulfonyl)piperazine,97%
  • 1-Methanesulfonyl-piperzaine
  • 1-Methanesulfonyl piperizine
  • 55276-43-2
  • C5H12N2O2SHCl
  • piperazines
  • Amines and Anilines
  • Heterocycles
  • Buildingblock