D-AP5

Product Name: D-AP5
CAS No.: 79055-68-8
Chemical Name: D-AP5
Synonyms: EIF4G2;D-AP5;IF4G2;D-APV;(R)-AP-5;Emasol L10;Emasol L 10;Emasol L-10;D-AP5(mM/ml);5-Phosphono-D-norvaline
CBNumber: CB3371309
Molecular Formula: C5H12NO5P
Formula Weight: 197.13
MOL File: 79055-68-8.mol

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D-AP5 Property

Melting point:: approximate 233℃
Boiling point:: 482.1±55.0 °C(Predicted)
Density: 1.529±0.06 g/cm3(Predicted)
RTECS: RD2513000
storage temp.: Store at RT
solubility: Soluble to 100 mM in sterile
form: White solid
pka: 2.46±0.10(Predicted)
color: White
Water Solubility: Soluble in water (100mM)
Sensitive: Light Sensitive

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A8054
Product name: D(?)-2-Amino-5-phosphonopentanoic acid
Purity: NMDA receptor antagonist
Packaging: 1mg
Price: $91.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 165304
Product name: D-(–)-2-Amino-5-phosphonopentanoic Acid
Packaging: 5mg
Price: $166
Updated: 2024/03/01

Alfa Aesar

Product number: J64887
Product name: (R)-(-)-2-Amino-5-phosphonopentanoic acid, 99%
Packaging: 10mg
Price: $325
Updated: 2024/03/01

Cayman Chemical

Product number: 14539
Product name: D-AP5
Purity: ≥95%
Packaging: 5mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 14539
Product name: D-AP5
Purity: ≥95%
Packaging: 10mg
Price: $100
Updated: 2024/03/01

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D-AP5 Chemical Properties,Usage,Production

Description

D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist (K_d = 1.4 μM) that competitively inhibits the glutamate binding site of NMDA receptors. Whereas D-AP5 is the active (−)-stereoisomer, its (+)-isomer (L-AP5) demonstrates considerably less potent NMDA receptor antagonist activity. AP5 has been widely used to study the activity of NMDA receptors particularly in regard to researching synaptic plasticity, learning, and memory.

Chemical Properties

white fine crystalline powder

Uses

A competitive NMDA antagonist

General Description

Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used competitive NMDA receptor antagonist.

Biological Activity

Widely used competitive NMDA antagonist. More active form of AP5. Also agonist at quisqualate-sensitized AP6 site where it is less potent than the L-isomer (L-(+)-2-Amino-5-phosphonopentanoic acid ). Also available as part of the Mixed NMDA Receptor Tocriset™ .

Biochem/physiol Actions

Product does not compete with ATP.

storage

Room temperature

D-AP5 Preparation Products And Raw materials

Raw materials

Preparation Products

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D-AP5 Suppliers

China 103 Germany 2 Japan 3 Switzerland 2 United Kingdom 7 United States 17 Global 134

EMMX Biotechnology LLC

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79055-68-8, D-AP5Related Search:

12AP ANTI-IGM MU-CHAIN, RAT AP CONJ ANTI-IGG H AND L CHAIN, GOAT AP CONJ DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID D-AP5 5-PHOSPHONOPENTANOIC ACID 4-AMINOBUTYLPHOSPHONIC ACID ANTI-IGG GAMMA-CHAIN, HUMAN AP CONJ ANTI-IGG, HUMAN AP CONJ ANTI-IMMUNOGLOBULIN A, HUMAN, AP ANTI-IGG, MOUSE AP CONJ 16-AP ANTI-IGG(H+L), HUMAN AP CONJ,ANTI-IGG H AND L CHAIN, HUMAN AP CONJ ANTI-IGG(H+L), RABBIT AP CONJ,ANTI-IGG H AND L CHAIN, RABBIT AP CONJ ANTI-IMMUNOGLOBULIN G, BOVINE, F(AB')2, AP ANTI-IGG H AND L CHAIN, HORSE AP CONJ ANTI-IMMUNOGLOBULIN G, CAT, F(AB')2, AP ANTI-IGM MU-CHAIN, HUMAN AP CONJ

D-AP5

D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID

D-2-AMINO-5-PHOSPHONOPENTANOIC ACID

D-(-)-2-AMINO-5-PHOSPHONOVALERIC ACID

D(-)-2-Amino-5-phosphonovaleric acid hydrate

D-(-)-2-AMINO-5-PHOSPHONOPENTANOIC ACID (D-AP5)

D-(–)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8 - Calbiochem

D(-)-AP-5, D(-)-APV, D-2-Amino-5-phosphonovaleric acid

(R)-2-aMino-5-phosphonopentanoic acid

(2R)-2-aMMonio-5-phosphonatopentanoate

Anti-EIF4G2, N-Terminal antibody produced in rabbit

Death associated protein 5

EIF4G2

Eukaryotic translation initiation factor 4 γ 2

IF4G2

D(-)-2-Amino-5-phosphonovaleric acid (D-AP5)

(2R)-2-Amino-5-phosphonovaleric acid

(R)-2-Amino-5-phosphonovaleric acid

(R)-5-Phosphono-2-aminovaleric acid

(R)-AP-5

D-APV

D(-)-2-Amino-5-phosphonovaleric acid hydrate,96%, (>98% ee)

D(-)-2-AMINO-5-PHOSPHONOPENTANOIC AC

5-Phosphono-D-norvaline

D(-)-2-AMINO-5-PHOSPHONOVALERIC ACID (D-AP5);5-PHOSPHONO-D-NORVALINE

D-Norvaline, 5-phosphono-

Emasol L 10

Emasol L10

Emasol L-10

(-)-2-Amino-5-phosphonovaleric acid

D-APV|||D-2-Amino-5-phosphonovaleric acid

D-AP5(mM/ml)

79055-68-8

C5H12NO5P

Glutamate

Glutamate receptor