ChemicalBook > CAS DataBase List > (-)-DIOP

(-)-DIOP

Product Name
(-)-DIOP
CAS No.
32305-98-9
Chemical Name
(-)-DIOP
Synonyms
(R)-DIOP;(-)-DIOP;(-)-Diop;(R,R)-DIOP;(4R,5R)-DIOP;phosphino)butane;(-)-2,3-O-IsopropyL;(2r,3r)-(-)-1,4-Bis(Diphenyl;idene-2,3-dihydroxy-1,4-bis(diphenyL;(4R,5R)-(-)-4,5-BIS(DIPHENYLPHOSPHINOMET
CBNumber
CB3371576
Molecular Formula
C31H32O2P2
Formula Weight
498.54
MOL File
32305-98-9.mol
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(-)-DIOP Property

Melting point:
88-90 °C(lit.)
alpha 
-26° (c 2.0, CHCl3)
Boiling point:
590.3±25.0 °C(Predicted)
storage temp. 
2-8°C
form 
Powder
color 
white
optical activity
[α]19/D 26°, c = 2.3 in chloroform
Sensitive 
Air Sensitive
BRN 
1441045
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37
WGK Germany 
3
F 
10-23
TSCA 
No
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
237655
Product name
(?)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
Purity
98%
Packaging
1g
Price
$360
Updated
2024/03/01
TCI Chemical
Product number
B1113
Product name
(2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol
Purity
>97.0%(T)
Packaging
1g
Price
$132
Updated
2021/12/16
Alfa Aesar
Product number
B21029
Product name
(-)-DIOP, 98%
Packaging
1g
Price
$103
Updated
2021/12/16
Alfa Aesar
Product number
B21029
Product name
(-)-DIOP, 98%
Packaging
250mg
Price
$39.4
Updated
2021/12/16
Strem Chemicals
Product number
15-2970
Product name
(4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane, 99.5% (R,R)-DIOP
Packaging
250mg
Price
$57
Updated
2024/03/01
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(-)-DIOP Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

For the in situ preparation of chiral hydrogenation catalysts.

General Description

(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane is a C2 chelating diphosphine ligand for transition metal complexes during asymmetric catalysis.

Purification Methods

It has been recrystallised from *C6H6/pet ether. After 2 recrystallisations from EtOH, it was pure by TLC on silica gel using Me2CO/hexane as solvent. [Kagan & Dang J Am Chem Soc 94 6429 1972.] Lanthanide shift reagents See in “Aliphatic Compounds”, Chapter 4, europium (III) acetate above and Eu(tmc)3 and Eu(tfc)3 below.

(-)-DIOP Preparation Products And Raw materials

Raw materials

p-Toluenesulfonic acid D-Tartaric acid Triethyl orthoformate Sodium Methanesulfonyl chloride Tetrahydrofuran (2S,3S)(-)-Dihydroxybutane-1,4-dioic acid diethyl ester Ethyl acetate Lithium Aluminum Hydride Dichloromethane Triphenylphosphine PETROLEUM ETHER Lithium

Preparation Products

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View Lastest Price from (-)-DIOP manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
(-)-DIOP 32305-98-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2023-04-07
Chemwill Asia Co.,Ltd.
Product
(-)-DIOP (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane 32305-98-9
Price
US $6.00/kg
Min. Order
1kg
Purity
High quality Professional Factory
Supply Ability
Ms Ella chemwill_asia@126.com www.chemwill.com
Release date
2019-04-04
Career Henan Chemical Co
Product
(-)-DIOP 32305-98-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg,5kg,100kg
Release date
2019-08-08

32305-98-9, (-)-DIOPRelated Search:

Isopropenylboronic acid pinacol ester (-)-Taddol ISOPROPENYLMAGNESIUM BROMIDE Flexol plasticizer diop (+)-DIOP,(S,S)-DIOP,(4S,5S)-(+)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(S,S)-DIOP (-)-DIOP 1,4-Bis(diphenylphosphino)butane 1,3-Dioxolane 2,2,4-TRIMETHYL-1,3-DIOXOLANE 2,2-Diethoxypropane Diphenylphosphine (2R,3R)-(+)-BIS(DIPHENYLPHOSPHINO)BUTANE 2,2-DIMETHYL-1,3-DIOXOLANE 2-METHYL-1,3-DIOXOLANE 2,4-DIMETHYL, 1,3-DIOXALONE BUTYLDIPHENYLPHOSPHINE 1,4-BIS(DIMETHYLPHOSPHINO)BUTANE (+)-MOD-DIOP

  • (2r,3r)-(-)-1,4-Bis(Diphenyl
  • (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, 98% 1GR
  • (4R,5R)-(-)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,99% (R,R)-DIOP
  • (4R,5R)-(-)-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane (-)-DIOP (2R,3R)-(-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
  • )-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(dipheny
  • (4R,5R)-(-)-2,2-Dimethyl-4,5-bis((diphenylphosphino)methyl)-1,3-dioxolane
  • (4R,5R)-(-)-4,5-Bis(diphenylphosphinoMethyl)-2,2-diMethyl-1,3-dioxolane,(R,R)-DIOP.
  • (-)-DIOP (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
  • (4R,5R)-(-)-4,5-BIS(DIPHENYLPHOSPHINOMET
  • (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)
  • 1,1'-[[(4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenylphosphine],99%e.e.
  • (4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2- dimethyl-1,3-dioxolane for synthesis
  • (4R,5R)-DIOP
  • (4R,5R)-trans-4,5-Bis[(diphenylphosphino)methyl]-2,2-dimethyl-1,3-dioxolane
  • (R)-DIOP
  • Isopropenyl-2,3-dihydroxy-1,4-Bis (diphenylphosphino) butane
  • 1,1'-[[(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenyl-Phosphine
  • (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
  • (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane 98%
  • (-)(2,3-O-isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane) OR (-)DIOP
  • (4R-TRANS)-[(2,2-DIMETHYL-1,3-DIOXOLANE-4,5-DIYL)BIS(METHYLENE)]BIS(DIPHENYLPHOSPHINE)
  • (-)-DIOP
  • (-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (R,R)-(-)-2,3-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYL-PHOSPHINO)BUTANE
  • (R,R)-DIOP
  • (3-chloro-2-hydroxypropyl) dihydrogen phosphate
  • (4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane,99.5%(R,R)-DIOP
  • Phosphine, (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diylbis(methylene)bisdiphenyl-
  • (-)-2,3-O-ISOPROPYLIDENE-2,3-*DIHYDROXY- 1,4-BIS(DIP
  • (-)-1,4-Bis-(diphenylphosphino)-2,3-dihydroxy-2,3-
  • (-)-DIOP, (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane, (4R,5R)-4,5-Bis(diphenylphosphino-methyl)-2,2-dimethyl-1,3-dioxolane
  • (R,R)-DIOP, (-)-1,4-Bis(diphenylphosphino)-1,4-dideoxy-2,3-O-isopropylidene-L-threitol, (4R,5R)-4,5-Bis(diphenylphosphino-methyl)-2,2-dimethyl-1,3-dioxolane, (4R-trans)-[(2,2-Dimethyl-1,3-dioxolane-4,5-diyl)bis(methylene)]bis(diphenylphosphine)
  • (4R)-2,2-Dimethyl-4β,5α-bis(diphenylphosphinomethyl)-1,3-dioxolane
  • [(4R,5R)-2,2-Dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)bis(diphenylphosphine)
  • [[(4R)-2,2-Dimethyl-1,3-dioxolane-4β,5α-diyl]bis(methylene)]bis(diphenylphosphine)
  • 2,2-Dimethyl-4β,5α-bis(diphenylphosphinomethyl)-1,3-dioxolane
  • (-)-1,4-BIS(DIPHENYLPHOSPHINO)-1,4-DIDEOXY-2,3-O-ISOPROPYLIDENE-L-THREITOL
  • (-)-2,3-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (2R,3R)-(-)-2,3-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (2R,3R)-(-)-1,4-BIS(DIPHENYLPHOSPHINO)-2,3-O-ISOPROPYLIDENE-2,3-BUTANEDIOL
  • (4R,5R)-(-)-BIS(DIPHENYLPHOSPHINOMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (4R 5R)-(-)-O-ISOPROPYLIDENE-2,3-DIHYDROXY-1,4-BIS(DIPHENYLPHOSPHINO)BUTANE
  • (4R,5R)-(-)-4,5-BIS(DIPHENYLPHOSPHINOMETHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (4R,5R)-4,5-BIS(DIPHENYLPHOSPHINO-METHYL)-2,2-DIMETHYL-1,3-DIOXOLANE
  • (2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol[(-)-DIOP]
  • (2R,3R)-(-)-1,4-Bis(diphenylphosphino)-2,3-O-isopropylidene-2,3-butanediol &gt
  • (4R,5R)-(-)-2,2-Dimethyl-4,5-bis((diphenylphosphino)methyl)-1,3-dioxolane, 97%, for synthesis
  • (-)-2,3-O-IsopropyL
  • idene-2,3-dihydroxy-1,4-bis(diphenyL
  • phosphino)butane
  • [(4R,5R)-5-(diphenylphosphanylmethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane
  • Phosphine, 1,1'-[[(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]bis(methylene)]bis[1,1-diphenyl-
  • (4R,5R)-(-)-2,2-Dimethyl-4,5-bis((diphenylphosphino)methyl)-
  • (-)-Diop
  • (-)-2,3-O-Isopropylidene-2,3-dihydroxy-1,4-bis(diphenylphosphino)butane
  • (-)-2,2-dimethyl-4,5-((diphenylphosphino)dimethyl)dioxolane
  • (R,R)-DIOP/(4R,5R)-(-)-4,5-Bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane
  • 32305-98-9