PINOCEMBRIN

Product Name: PINOCEMBRIN
CAS No.: 480-39-7
Chemical Name: PINOCEMBRIN
Synonyms: Picembrin;PINOCEMBRIN;pinocemberin;dihydrochrysin;Pinocembrin-RM;PINOCEMBRIN(RG);(+)-Pinocembrin;galanginflavanone;5,7-DIHYDROXYFLAVANONE;4H-1-BENZOPYRAN-4-ONE,2,3-DIH
CBNumber: CB3378883
Molecular Formula: C15H12O4
Formula Weight: 256.25
MOL File: 480-39-7.mol

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PINOCEMBRIN Property

Melting point:: 202 °C
Boiling point:: 511.1±50.0 °C(Predicted)
Density: 1.386±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in ethanol and methan
form: powder
pka: 7.50±0.40(Predicted)
color: White
LogP: 3.225 (est)
EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2S)- (480-39-7)

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Safety

Safety Statements: 24/25
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29852
Product name: Pinocembrin
Packaging: 10mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 29852
Product name: Pinocembrin
Packaging: 250mg
Price: $796
Updated: 2024/03/01

Cayman Chemical

Product number: 29852
Product name: Pinocembrin
Packaging: 50mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 29852
Product name: Pinocembrin
Packaging: 100mg
Price: $363
Updated: 2024/03/01

Biosynth Carbosynth

Product number: XP162085
Product name: (+)-Pinocembrin
Packaging: 1g
Price: $550
Updated: 2021/12/16

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PINOCEMBRIN Chemical Properties,Usage,Production

Description

Pinocembrin is a flavonoid that has been found in Eucalyptus, and has diverse biological activities. It induces apoptosis in, and inhibits the migration of, SKOV3 ovarian cancer cells when used at a concentration of 200 μM. Pinocembrin (5 mg/kg) reduces lesion volume, as well as brain microglial activation and production of IL-1β, IL-6, and TNF-α in a mouse model of collagenase-induced intracerebral hemorrhage (ICH). It prevents increases in plasma and kidney malondialdehyde (MDA) levels, glomeruli lobulation, mesangial expansion, and tubule vacuolization and occlusion, and it decreases hepatic cholesterol, triglyceride, and LDL levels in a rat model of diabetic nephropathy. Pinocembrin (20 and 50 mg/kg) reduces pulmonary edema, as well as neutrophil, lymphocyte, and macrophage infiltration in a mouse model of LPS-induced lung injury.

Chemical Properties

Solid

Uses

Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.

Definition

ChEBI: Pinocembrin is a dihydroxyflavanone in which the two hydroxy groups are located at positions 5 and 7. A natural product found in Piper sarmentosum and Cryptocarya chartacea. It has a role as an antioxidant, an antineoplastic agent, a vasodilator agent, a neuroprotective agent and a metabolite. It is a dihydroxyflavanone and a (2S)-flavan-4-one.

PINOCEMBRIN Preparation Products And Raw materials

Raw materials

Preparation Products

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PINOCEMBRIN Suppliers

Canada 1 China 194 Germany 2 India 2 Japan 1 United Kingdom 5 United States 18 USA 1 Global 224

EMMX Biotechnology LLC

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View Lastest Price from PINOCEMBRIN manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: PINOCEMBRIN 480-39-7
Price: US $1.00-2.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20000KG
Release date: 2024-08-09

Shanghai Standard Technology Co., Ltd.

Product: Pinocembrin 480-39-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-25

Career Henan Chemical Co

Product: PINOCEMBRIN 480-39-7
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10tons
Release date: 2018-12-24

480-39-7, PINOCEMBRINRelated Search:

Naringenin NARIRUTIN PONCIRIN ERIODICTYOL-7-GLUCOSIDE 5,7-DIHYDROXY-3',4',5'-TRIMETHOXYFLAVANONE Pinostrobin HESPERETIN ERIOCITRIN PINOCEMBRIN ISOSAKURANETIN 6,8-DIMETHYL-4',5,7-TRIHYDROXYFLAVANONE Neohesperidin PINOCEMBRIN PINOCEMBRIN DIMETHYL ETHER PINOCEMBRIN-7-METHYLETHER(RG),PINOCEMBRIN-7-METHYL ETHER PINOCEMBRIN DIMETHYL ETHER FLAVANONE (+/-)-TAXIFOLIN

5,7-DIHYDROXYFLAVANONE

5,7-DIHYDROXY-3'4'5'-FLAVANONE

5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE

PINOCEMBRIN

(s)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4h-1-benzopyran-4-one

3-dihydro-5,7-dihydroxy-2-phenyl-(s)-4h-1-benzopyran-4-on

dihydrochrysin

galanginflavanone

PINOCEMBRIN(RG)

4H-1-BENZOPYRAN-4-ONE,2,3-DIH

PinoceMbrin, froM Pinus cerebra

(2S)-2-Phenyl-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one

(2S)-2α-Phenyl-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one

Picembrin

(2S)-5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one

5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one

Pinocembrin, 98%, from Pinus cerebra

(2S)-5,7-Dihydroxy-2-phenylchroman-4-one

4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2S)-

(S)-5,7-Dihydroxy-2-Phenylchroman-4-One

pinocemberin

(+)-Pinocembrin

Inhibitor,Bacterial,Autophagy,Reactive Oxygen Species,(+)-Pinocoembrin,inhibit,Pinocembrin

Pinocembrin-RM

480-39-7

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Flavanones