ChemicalBook > CAS DataBase List > 4-Bromobenzenesulfonamide

4-Bromobenzenesulfonamide

Product Name
4-Bromobenzenesulfonamide
CAS No.
701-34-8
Chemical Name
4-Bromobenzenesulfonamide
Synonyms
AKOS 206-12;p-bromo-benzenesulfonamid;P-BROMOBENZENESULFONAMIDE;4-BROMOBENZENESULFONAMIDE;Bromo Benzene Sulphonamide;4-BROMOBENZENESULPHONAMIDE;Benzenesulfonamide, p-bromo-;Benzenesulfonamide, 4-bromo-;4-Bromobenzenesulphonamide 98%;4-Bromobenzenesulphonamide-98%
CBNumber
CB3379855
Molecular Formula
C6H6BrNO2S
Formula Weight
236.09
MOL File
701-34-8.mol
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4-Bromobenzenesulfonamide Property

Melting point:
163-167 °C
Boiling point:
360.7°C (rough estimate)
Density 
1.8000 (estimate)
refractive index 
1.6140 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
9.89±0.10(Predicted)
color 
White to Off-White
Water Solubility 
991.6mg/L(15 ºC)
BRN 
2691657
InChIKey
STYQHICBPYRHQK-UHFFFAOYSA-N
CAS DataBase Reference
701-34-8(CAS DataBase Reference)
NIST Chemistry Reference
4-Bromobenzenesulfonamide(701-34-8)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
DB0550000
HazardClass 
IRRITANT
HS Code 
2935909099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
16374
Product name
4-Bromobenzenesulfonamide
Purity
≥99.0% (T)
Packaging
5g
Price
$51.66
Updated
2024/03/01
Sigma-Aldrich
Product number
16374
Product name
4-Bromobenzenesulfonamide
Purity
≥99.0% (T)
Packaging
100g
Price
$128
Updated
2022/05/15
TRC
Product number
B682628
Product name
4-Bromobenzenesulfonamide
Packaging
500mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
AMTH168
Product name
4-Bromobenzenesulfonamide
Packaging
5g
Price
$10
Updated
2021/12/16
Apolloscientific
Product number
OR30462
Product name
4-Bromobenzenesulphonamide
Purity
98%
Packaging
5g
Price
$16
Updated
2021/12/16
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4-Bromobenzenesulfonamide Chemical Properties,Usage,Production

Uses

4-Bromobenzenesulfonamide was used as reagent in preparation of cobalt(III) complexes of N,R-sulfonyldithiocarbimate anion. It was also used in the synthesis of 2-, 3- and 4-(substituted-phenylethynyl)benzenesulfonamides.

General Description

4-Bromobenzenesulfonamide is a metabolite of ebrotidine, a new H2-receptor antagonist.

Synthesis

98-58-8

701-34-8

Preparation of 4-bromobenzenesulfonamide: 4-bromobenzenesulfonyl chloride (1.0 g, 3.9 mmol) was dissolved in methanol (5 mL), methanol/ammonia solution (5 mL, excess) was added, and the mixture was mixed in a 25 mL single-neck flask. The reaction mixture was stirred overnight at room temperature under nitrogen protection. On the next day, the reaction solution was concentrated under reduced pressure to give p-bromobenzenesulfonamide (1.13 g, 100% yield) as a white solid. The product was confirmed by ion spray mass spectrometry (m/z 235.9 [M*]) and could be used for subsequent reactions without further purification.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 14, p. 3880 - 3885
[2] Patent: US2004/63680, 2004, A1
[3] Patent: US7034045, 2006, B1. Location in patent: Page/Page column 83
[4] Journal of Medicinal Chemistry, 2018, vol. 61, # 11, p. 4860 - 4882
[5] RSC Advances, 2014, vol. 4, # 24, p. 12119 - 12126

4-Bromobenzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Bromobenzenesulfonamide manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Bromobenzenesulfonamide 701-34-8
Price
US $1.00-4.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2025-09-04
Shaanxi Dideu New Materials Co. Ltd
Product
4-Bromobenzenesulfonamide 701-34-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-05-08
Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Bromobenzenesulfonamide 701-34-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2025-03-13

701-34-8, 4-BromobenzenesulfonamideRelated Search:


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  • AKOS 206-12
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  • 4-BROMOBENZENESULFONAMIDE, 98 %
  • 4-Bromobenzenesulfonamide USP/EP/BP
  • 4-Bromobenzenesulfonamide ISO 9001:2015 REACH
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