4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE

Product Name: 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE
CAS No.: 162641-16-9
Chemical Name: 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE
Synonyms: CS-620;HQL-97;HQL-79;HQL 79;HQL79;4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine;1-(3-(1H-Tetrazol-5-yl)propyl)-4-(benzhydryloxy)piperidine;4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine;4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE;Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-
CBNumber: CB3399336
Molecular Formula: C22H27N5O
Formula Weight: 377.48
MOL File: 162641-16-9.mol

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4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Property

Boiling point:: 553.6±60.0 °C(Predicted)
Density: 1.21
storage temp.: Store at RT
solubility: DMSO: soluble2mg/mL, clear (warmed)
form: powder
pka: 4.85±0.10(Predicted)
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0857
Product name: HQL 79
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $72.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0857
Product name: HQL 79
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $417
Updated: 2025/07/31

Cayman Chemical

Product number: 10134
Product name: HQL 79
Purity: ≥98%
Packaging: 1mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 10134
Product name: HQL 79
Purity: ≥98%
Packaging: 5mg
Price: $120
Updated: 2024/03/01

Cayman Chemical

Product number: 10134
Product name: HQL 79
Purity: ≥98%
Packaging: 10mg
Price: $146
Updated: 2024/03/01

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4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Chemical Properties,Usage,Production

Uses

HQL-79 is a selective PGE synthase inhibitor.

Biological Activity

HQL 79 is an orally active anti-allergic agent th at acts as an antagonist for histamine H1 receptors (H1R), eliciting anti-asthmatic effects. It interacts with prostaglandin (PG) D synthase (H-PGDS) in the catalytic region. It may be potential lead due to its H-PGDS inhibition to tre at allergies.', 'HQL-79 is a selective inhibtor of hematopoietic prostaglandin D (PGD) synthase, one of two synthases involved in the production of Prostaglandin D2 (PGD2) from arachidonic acid. PGD2 is a lipid signaling molecule, which activates two receptors, DP1 involved in centrally mediated processes such as sleep and pain and DP2 involved and inflammation. The two PGD synthases involved in its synthesis are lipocalin-type (L-PGDS) and hematopoietic (H-PDGS), which acts to form PGD2 in mast cells, Th2 cells, microglia, and other inflammatory cells/tissues. HQL-79 selectively inhibited the activity of recombinant H-PGDS with an IC50 of 6 μM and had almost no effect on COX-1, COX-2, m-PGES, or L-PGDS up to 300 μM. HQL-79 has anti-inflammatory activity in vitro and in vivo.

storage

Store at RT

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE Suppliers

China 78 Switzerland 1 United Kingdom 3 United States 15 Global 97

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View Lastest Price from 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE manufacturers

Career Henan Chemical Co

Product: 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE 162641-16-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-13

162641-16-9, 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINERelated Search:

(S)-(+)-Benzyl glycidyl ether Phenethyl alcohol Titanium tetrachloride potassium 2-hydroxy-4-methoxybenzoate p-Anisidine Guaiacol Diphenylphosphine oxide diphenylpyraline 4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE 4-(DIPHENYLMETHOXY)PIPERIDINE

HQL-79

4-(Diphenylmethoxy)-1-(3-2H-tetrazol-5-yl)propyl]-piperidine

HQL-97

4-(DIPHENYLMETHOXY)-1-[3-(1H-TETRAZOL-5-YL)PROPYL]-PIPERIDINE

CS-620

HQL 79;HQL79

Piperidine, 4-(diphenylmethoxy)-1-[3-(2H-tetrazol-5-yl)propyl]-

1-(3-(1H-Tetrazol-5-yl)propyl)-4-(benzhydryloxy)piperidine

4-benzhydryloxy-1-[3-(2H-tetrazol-5-yl)propyl]piperidine

162641-16-9

C22H27N5O