METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE
- Product Name
- METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE
- CAS No.
- 170235-26-4
- Chemical Name
- METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE
- Synonyms
- CAS:170235-26-4;2-Bromo-4-(methoxycarbonyl)-1,3;2-broMidethiazol -4-Methyl forMate;Methyl 2-Bromo-4-thiazolecarboxylate;METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE;Methyl 2-Bromothiazole-4-Carboxylate sky;2-Bromo-4-(methoxycarbonyl)-1,3-thiazole;Methyl 2-Bromothiazole-4-carboxylate >Methyl 2-bromo-1,3-thiazole-4-carboxylate;2-Bromothiazole-4-carboxylicacidmethylester95%
- CBNumber
- CB3424829
- Molecular Formula
- C5H4BrNO2S
- Formula Weight
- 222.06
- MOL File
- 170235-26-4.mol
METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE Property
- Melting point:
- 118-122
- Boiling point:
- 263.3±13.0 °C(Predicted)
- Density
- 1.759±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- Solid
- pka
- -1?+-.0.10(Predicted)
- color
- White to Light yellow
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C5H4BrNO2S/c1-9-4(8)3-2-10-5(6)7-3/h2H,1H3
- InChIKey
- YOWKNNKTQWCYNC-UHFFFAOYSA-N
- SMILES
- S1C=C(C(OC)=O)N=C1Br
- CAS DataBase Reference
- 170235-26-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M2615
- Product name
- Methyl 2-Bromothiazole-4-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $48
- Updated
- 2025/07/31
- Product number
- M2615
- Product name
- Methyl 2-Bromothiazole-4-carboxylate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $145
- Updated
- 2025/07/31
- Product number
- M219300
- Product name
- Methyl 2-Bromothiazole-4-carboxylate
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- M219300
- Product name
- Methyl 2-Bromothiazole-4-carboxylate
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- HCH0026334
- Product name
- METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $642.99
- Updated
- 2021/12/16
METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE Chemical Properties,Usage,Production
Chemical Properties
Yellow-brown powder
Uses
It is employed as a intermediate for pharmaceutical.
Synthesis
The synthesis of methyl 2-bromothiazole-4-carboxylate is as follows:
The crude ethyl ester 228 (12.7 g) was dissolved in methanol (150 mL), and concentrated sulfuric acid (1 mL) was added. The mixture was heated to reflux for 12 hr (TLC control). The solvent was evaporated, the residue was diluted with H2O (150 mL), neutralized with saturated sodium bicarbonate solution, and extracted with dichloromethane (4 x 100 mL). The combined extracts were dried with sodium sulfate and concentrated. Purification by column chromatography (silica gel, 80 g, ethyl acetate/cyclohexane = 1:15) gave 6.5 g methyl ester 230 (29.4 mmol, 49 % over three steps) as a colorless solid. TLC: Rf = 0.55 (ethyl acetate/cyclohexane = 1:2).
METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE manufacturers
- Product
- METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE 170235-26-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-06-29
- Product
- Methyl 2-bromothiazole-4-carboxylate 170235-26-4
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-07-12
- Product
- METHYL 2-BROMOTHIAZOLE-4-CARBOXYLATE 170235-26-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2018-08-06